No 4(2) (2012)
CLINICAL MEDICINE
9-11 564
Abstract
The aim. of our study was to analyze clinical and laboratory features of acute mesenteric ischemia course and to reveal possible ways to improve patients care in this category in non-specialized. multidisciplinary medical institution. The study is based, on the analysis of case histories of patients treated, in the ward of general surgery of Railway Clinical Hospital of Chita in 2007—2011 years with acute mesenteric ischemia as well as the analysis of autopsy protocols of this category of patients. Analysis of clinical records revealed, a number of symptoms, the presence of which in people of group of risk on the acute mesenteric ischemia allows to diagnose and. to start pathogenetic therapy in the first hours of the disease.
12-15 452
Abstract
The article presents the results of retrospective analysis of treatment of patients with, combined trauma in the condition of traumatic shock for 2007—2011 according to the data of City Clinical Emergency Hospital named after V.V. Angapov.
16-20 452
Abstract
On the basis of commonly used morphometric and additional new indices at the research, of vertebromotor segment, dural sack and vertebral canal in 48 patients Zn coefficient was calculated mathematically. Its value corresponds to the degree of stenosing process of vertebral canal and. defines the degree of gravity of clinical and. neurological disorders in studied patients.
21-25 385
Abstract
The article presents the analysis of four most common classifications of subaxial injuries of cervical segment of spine. Clinical testing of treatment-tactical algorithm, presented, in the article was realized. Succession of the classification, with the choice of treatment tactics was showed.
26-30 469
Abstract
By atomic force microscopy we realized the research of anatomic material represented by the fragments of tissue of intervertebral disks of different stages of degenerative process. The researches were carried out with help of probe nanolaboratory with videomicroscope Ntegra Prima. As the result we obtained direct experimental data that proves some theoretical investigation that hadn't had. visual proves.
31-34 465
Abstract
Prevention of deep vein thrombosis and pulmonary artery thromboembolism using heparin is a gold standard in orthopedics. The aims of the work were to evaluate and to compare efficiency and. safety of thromboprophylaxis in orthopedics using Pradaxa and Clexane in long-term follow-up. 96 patients are included in research. Follow-up information on all patients was collected either through telephone contact with the patients or by questionnaire. Conclusions: The number of respondents appeared insufficient for the actual check of an initial hypothesis. In modeling outcomes plausibility of a hypothesis isn't disproved. Recommendations about VTE prevention after discharge in our study are differed from the accepted standards.
35-38 552
Abstract
We carried out the analysis of results of treatment of patients with early periprosthetic infection after total hip replacement with use of tactics aimed at the preservation of an implant and function of the operated joint, based on a multi-stage surgical rehabilitation, clinical and. laboratory monitoring of the wound healing process. The efficiency of chosen tactics in 83 % of cases was shown. Based on these results an algorithm for treatment of early periprosthetic infection at the hip replacement that can be recommended for widespread use in clinical practice was offered.
39-42 813
Abstract
Main clinical syndromes of non-specific purulent diseases of spine are neurological, including pain (vertebrogenous) syndrome and syndrome of systemic inflammatory response. All patients were divided into two groups: 1st - control group (50 patients with non-specific purulent diseases of spine without syndrome of systemic inflammatory response), 2nd - main group (70 patients with non-specific purulent diseases with syndrome of systemic inflammatory response). Main indications for the operation were surgical decompression of neurovascular formations of spine canal and. sanation of suppurative focus in vertebras. Complex approach to the treatment of septic patients by optimization of surgical tactics and. choice of susceptible antibacterial therapy allows to achieve positive outcomes of surgical treatment in most cases.
43-48 590
Abstract
Peculiarities of composition of protein fractions and acute-phase liquor proteins as the indications of activity of immunologic liquor reactions were studied by biochemical method in 15 patients without neurological diseases and. in 36 patients with compression syndrome of lumbar region of spine. On this base the set of standard data of acute-phase liquor proteins was developed. The Peculiarities of composition of acute-phase liquor proteins in patients with compression syndrome of lumbar region of spine were itemized. Interrelation of changes of acute-phase liquor proteins in norm. and. at compression syndrome of nervous structure of lumbar region of spine was determined.
49-55 533
Abstract
Concentrations and composition of acute-phase proteins in liquor were studied by method of ultraviolet absorption. spectroscopy in 15 patients without neurological diseases and. in 25 patients with syndrome of spinal canal structures compression. The role of acute-phase proteins of liquor in forming of epidural fibrosis was determined. Significance of denaturated proteins of liquor in pathogenesis of syndrome of compression of lumbar segment of spine was revealed.
56-59 717
Abstract
23 patients operated on account of large and huge postoperative ventral hernias were examined. It was revealed that in spite of preventive measures realized before the operation the increase of intra-abdominal pressure was registered in 34,8 % of cases. Manifestations of intra-abdominal hypertension syndrome appeared in 26 % of patients. Significant connection between the sized of hernial outpouching, diameter of hernial gates and. the level of intra-abdominal hypertension and. also frequency of intra-abdominal hypertension syndrome that testifies to the expediency of search of new ways to prevent development of this postoperative complication. Key words: postoperative ventral hernia, intra-abdominal hypertension syndrome
60-63 521
Abstract
Obstructive jaundice is one of the most frequent complications of cancer of pancreatobiliary zone that starts the developments of hemorrhagic complications. This group of patients has decrease of coagulation potential that is expressed in changes of process of thrombin generation even before the operative treatment. The article presents the results of the research of indices of process of thrombin generation by Calibrated. Automated. Thrombogram. method in 57 patients with cancer of pancreatobiliary zone complicated with obstructive jaundice before the operative treatment.
64-67 535
Abstract
The article reviews epidemiology of acute pain syndrome in urgent and elective otorhynolaryngology. 161 patients with acute pain on the background of acute ENT diseases (group 1) and 130 patients immediately after routine surgery were questioned. Total values on the pain level of the patients of the group 1 showed that 27,32 % of patients had. mild pain, 30,43 % of patient had. medium pain, 31,05 % had. strong pain and. 11,18 % had. very strong pain. In the group 2 25,38 % of patients had low pain level, 40,76 % had medium pain level, 26,92 % had. highpain level and. 6,92 % had. very high pain level. Understanding of pain syndrome structure at different ENT disorders helps in choice of adequate analgetic therapy and prevents development of chronic pain syndrome.
68-71 1596
Abstract
We researched acute postoperative pain in patients with nasal septum deviation (group 1; 25 patients) and with polypoid rhinosinusitis (group 2; 31 patient) by means of analogue scales (AS) and. McGill Pain Questionnaire (MPQ). High correlation coefficients between AS and. MPQ values - 0,80 and. 0,77 in group 1 and. group 2 agreeably - were obtained. Strong reliable connection (p < 0,01) between AS and. MPQ values was proved. While evaluating sensory, affective and. evaluative components of MPQ low level of pain in both groups was revealed.
72-76 480
Abstract
The role of ultrasonic research, in diagnostics of acute pathological changes of gastrointestinal tract was showed. The advantages of the method, and the indications to its use at various pathologies in children are precisely described.
77-82 458
Abstract
Main reason of shoulder joint instability is bone defect of scapula cavity. The number of unsatisfactory outcomes after surgical treatment is still high. The aim. of the research was to improve surgical technique of treatment of patients with chronic posttraumatic anteromedial instability of shoulder joint at the bone defect of articular process of the scapula. Open controlled prospective randomized research was carried out in the clinics of SCRRS SB RAMS. Clinical effectiveness of proposed medical technology was proved on the basis of analysis of operative treatment of 34 patients during 6 months after the operation. We used Bristow - Latarjet bone plastics for comparison.
83-88 482
Abstract
The article presents our own experience of treatment of Hirschsprung disease in adults.
89-91 438
Abstract
The clinical studies involved. 27 operated patients with acute varicothrombophlebitis treated in the department of vascular surgery of Orenburg Municipal Clinical Hospital named after N.I. Pirogov in 2011-2012. We proved the necessity of control ultrasound examination of veins of lower extremities at the varicothrombophlebitis in 1 and 7 days after admission to the hospital to diagnose the thrombosis progress despite of clinical manifestations of the disease. This allows to carry out the sapheno-femoral crossectomy promptly and. to prevent the risk of development of pulmonary thromboembolism.
92-95 491
Abstract
The estimation of state of vegetative nervous system (by cardiointervalography) in 20 children and. adolescents of 10-17 years (13,5 ± 2,1 years in average) with dysplastic coxarthrosis was realized. The study showed that before the treatment increase of activity of sympathetic nervous system prevails. During the first week after surgery acetylcholine type of regulation of heart rate accompanied by increased activity of sympathetic division of vegetative nervous system was registered. Postoperative treatment time (during 1 month) and. increased physical activity contribute to the restoration of regulatory systems to the original level. During the treatment by Ilizarov apparatus the decrease of level of tolerance to hypoxia and. decrease of processes of general adaptation are registered.
96-100 665
Abstract
The article presents the results of researches of fatty aldehydes and total cholesterol of blood plasma of patients with multiple organ dysfunction syndrome. On the basis of determined significant decrease of analyzed compounds level we concluded about possibility of peroxysomal dysfunction at this syndrome. The article cites literary data that indicate significant role of peroxisomes in the formation of severe metabolic disturbances and. the development of inflammatory reactions.
101-105 459
Abstract
According to the retrospective analysis of combined lethal trauma in 105 children, the frequency of spleen trauma is 31,4 %. The risk of death, from intraabdominal bleeding at the spleen trauma is very low (OR = 0,16; 95% CI 0,019-1,34; p = 0,04). At the spleen trauma the volume of hemothorax considerably exceeded the volume of hemoperitoneum (977 ± 866,9 ml vs 311 ± 270,3 ml; p < 0,0003). The risk of death from the bleeding in thoracic cavity 45 times higher than the one from bleeding in abdominal cavity. The degree of spleen injury in children has low correlation with, trauma mechanism (r = 0,17; p < 0,37) and with the volume of hemoperitoneum (r = 0,1; p < 0,5). The probability of death from injury at the scene is low (OR = 0,09; 95% CI 0,0096-0,84; p < 0,017). The main causes of children's death, at the combined injury are cranial trauma, hemorrhagic shock at thoracic trauma and. traumatic shock.
106-109 470
Abstract
We realized dynamic control of pain syndrome intensity after toлsillectomy in. 24 patients. In. 2 hours after the operation 80 % of patients had. medium, and. strong рат, in 1 day 25 % had. weak рат and. 50 % - medium рат. On the 3rd day 54 % of patients had. weak pain or didn't have pain syndrome at all. Determination of pathogenetic variant of pain syndrome: in 2 hours after the operation 62,5 % of patients had. psychogenic pain syndrome, 25 % - neurogenic; in 1 day 41,7 % had. psychogenic and. 33,3 % - neurogenic; in 3 days 41,7 % had. somatogenic pain syndrome, 29,2 % - psychogenic and. 21 % didn't have pain syndrome. It's necessary to diagnose pain syndrome at the early stage after tonsillectomy with help of analogue scales of pain evaluation. It seems prospective to determine pathogenetic variant of acute pain with help of verbal-color scale and. elaboration of analgetic therapy, that is corresponding to the pathogenetic variant, for the patients after tonsillectomy.
110-113 439
Abstract
The article presents the results of diagnostics and treatment of 79 patients with pathology of caudal regions of neural tube - fixed spinal cord. On the basis of methods of neurovisualization and. electrophysiology the screening of revealing of pathology of spinal cord (fixed spinal cord) that allows to define the strategy and. tactics of treatment and. to predict outcomes of the disease.
114-117 415
Abstract
The presented work is based on the analysis of the results of complex conservative and surgical treatment of 179 patients with pancreatonecrosis which were on treatment in surgical departments of Republican hospital N 2 - Emergency Center of Sakha (Yakutia) Republic during 2008-2010 years. During the research it became possible to reveal that application of regional intra-arterial drug therapy in complex treatment of patients with pancreatonecrosis allows to stop cases of endogenous intoxication more quickly and. effectively that increased the probability of a favorable outcome of the disease and. reduced the period of stay of patients in a hospital.
118-121 483
Abstract
150 patients with varicose disease in great saphenous vein system. (GSV) were examined with the help of ultrasound duplex scanning. Location and. quantity of valves and. varicose nodes in GSV were defined, the diameter of supplementary anterolateral and posteromedial inflows was measured and. the location of their confluence into GSV was determined. Comparison of data obtained during the ultrasound examination with the results of macro-microscopic investigation of distant GSV was carried out. The obtained data are evidence about the necessity of preoperative ultrasound mapping of varicose nodes and. the investigated inflows location. and. about their obligatory ligation for prevention of subcutaneous haematomas formation on the thigh after saphenectomy.
122-125 595
Abstract
After one-stage transhiatal esophagoplasty more than 1 year ago for benign esophageal diseases GIQLI questionnaire was completed by 30 patients after esophageal extirpation with gastric tube esophagoplasty and 25 patients after bypassing esophagoplasty with left colon. Based on type of esophagoplasty and. follow-up period. (1-3 years, 3 and. more years) patients were divided up into 4 groups. Statistic analysis revealed evidently (p<0,01) higher GIQLI in patients 3 and. more years after esophagogastroplasty in comparison with other groups of respondents. Generally, without taking follow-up period into account, GIQLI was higher in patients with gastric tube esophagoplasty than after left colon esophagoplasty (p<0,01).
126-130 404
Abstract
35 patients were examined in 3-10 years after transhiatus esophageolpastics on account of esophageal achalasia were examined. It was determined at X-ray and. endoscopic examination that transplant held tubular shape without considerable deformations, tended to the atrophy and moderate focal hyperemia of mucous tunic and also underwent bile reflux. In 5 cases we revealed first time appeared stenosis of esophagogastric anastomosis, permeability of which was restored by endoscopic method in all patients. Dystrophic changes and. high secretion of superficial epithelium dystrophy and. focal atrophy of fundus glands, cellular infiltration of stroma, thickening and. fibrosis of muscular layer of mucous tunic of gastric tube were revealed microscopically in biopsy material. Revealed morphofunctional peculiarities of transplant testify to the realization of a complex of adjustments and. pathological reactions in it and. dynamic control of course of these reactions is considered necessary at the patients' mass health examination.
131-135 555
Abstract
The article reviews modern approaches in complex treatment of patients with diabetic foot syndrome. Authors present their experience with the patients who arrived in planned and emergency order, the criteria of choice of the strategy of surgical treatment of diabetic foot syndrome. Direct and remote results of introduced scheme are studied and. its advantages and. disadvantages are revealed.
136-140 542
Abstract
The aim. of the research was to create diagnostic method for determination of attitude position of elements of femur proximal segment for understanding of development of hip joint pathology and determination of surgical tactics of treatment. The method of precise determination of angle interrelations between the elements of hip joint with use of multispiral computed tomograms. Offered method of diagnostics of estimation of position of elements of femur proximal segment is a necessary way of research of understanding for development of degenerative changes in hip joint and. also for determination of tactics and. method of treatment.
141-144 417
Abstract
2 groups of patients of different age with varus deformity of lower extremities bones (19 patients with phosphate-diabetes (PD) and 36 patients without this disease) were examined. Control group consisted of 50 healthy female coevals. Patients with PD had. lag in lengthwise body growth, decrease of contractive ability of extremities' muscles, decrease of speed and power characteristics of locomotions, decrease of availability. Patients with,deformations of bones but without PD had. decrease of shin muscle power, weakening of balance function of a foot and. decrease of load, on foot segments while walking.
145-147 451
Abstract
The results of treatment of 35 patients with acute pancreatitis of alcoholic etiology were studied. It was shown that application of thioctic acid in a dose of 600 mg/day in with minimally invasive surgeries in complex treatment allows to localize the process and. to treat it in an aseptic way.
148-149 394
Abstract
We analyzed the results of treatment of 30 patients who had. cystectomy with different methods of urine diversion. The postoperative course of patients after cystectomy is determined, by the extent of the operation, method of urine derivation, volume of intraoperative hemorrhage, time of recovery of intestinal peristalsis, continuance of lymphorrhea, complications (appeared or not), and patient's condition before the operation.
150-154 468
Abstract
The article presents the results of bariatric surgeries carried out in the clinic in patients with morbid obesity. We traced both the nearest and remote results after treatment, the loss of body weight in dynamics, relief of the manifestations of "metabolic syndrome" as well as we estimated the quality of life of patients in pre-and postoperative period.
155-158 411
Abstract
The research of content of primary and secondary (lipohydroperoxides, malondialdehyde) products of free radical oxidation of lipids in blood serum, and. indices of activity of antioxidant enzymes (glutathione peroxidase and. glutathione reductase) in 62 patients with pancreatic diabetes of type II. In 28 patients of them, the disease was complicated by suppurative inflammation of the foot. On the basis of these data we proposed a method of forecasting of the development of infectious complications in these patients at the stage of pre-clinical manifestations. This allows to make necessary pharmacological correction in the treatment of patients with pancreatic diabetes promptly to prevent the development of diabetic foot syndrome.
EXPERIMENTAL RESEARCHES IN BIOLOGY AND MEDICINE
159-162 461
Abstract
The article presents the materials of experimental study of Terizidone preparation in conditions of single peroral influence on animals in different doses with a view to reveal response of an organism for using in the evaluation of general toxic action of an advanced antituberculous preparation.
163-166 393
Abstract
The article presents the materials of experimental study of Terizidone in combination with pyridoxine hydrochloride in conditions of single peroral influence on animals in different doses with a view to reveal response of an organism for using in the evaluation of general toxic action of an advanced antituberculous preparation.
167-169 454
Abstract
The article reviews possibility of use of integral index of evaluation of condition of lipid peroxidation and. antioxidant protection processes in toxicological researches. Definite results of use of dihydroquercetin antioxidant at the dicyclopentadiene poisoning are presented.
170-174 498
Abstract
Aim: to base and to test new more precise way of determination of the type of adaptation strategy and. intensity of corresponding metabolic shifts in experiment. Methods: the model of orthopedic trauma of two extremities with stabilization of fragments with external fixation devices was rendered in experimental group of 22 chinchilla rabbits. We defined oxygen consumption, carbonic acid excretion and rectal temperature initially and also on the 1st, 3rd and 7th day after the operation. Results. Addition of data of research of oxygen consumption (key criterion of the type of adaptation strategy) with the results of determination of carbonic acid excretion and rectal temperature, correct choice of initial condition of laboratory animal that will be compared and also quantitative characteristics of intensity of metabolic shifts allowed to increase exactness of diagnostics of type of adaptation strategy of laboratory animals in unfavorable conditions.
175-178 452
Abstract
The article presents the results of research of femoral head morphology at the III-IV stage of coxarthrosis. Tissue reorganization in femoral head is shown.
179-184 471
Abstract
It was established, that ethanol in the dose of 12 g/kg in experimental animals (white non-inbred male rats) had. expressed damaging effect on the liver, that is shown in statistically significant increase of activity of hepatic enzymes (alanine aminotransferase, alkaline phosphatase), hypoglycemia, development of albuminous and. hydropic degeneration. It is proved, that application of new chelate zinc (2,8,9-trigidrotsinkatrane) in experimental correction of acute ethanol poisoning promotes reduction of metabolic and morphological derangements.
185-189 425
Abstract
The article is devoted to the study of development of reparative osteogenesis at the healing of bone wounds with and. without using of vibration. Experiments were performed in 10 hamsters of more than 45 days. They had. foramen made manually in lower part of diaphysis of thigh-bone by the drill of 1,5 mm. in diameter. In one day in 5 animals we realized stimulation of osteogenesis by directional mechanical oscillations with frequency 10 Hz, amplitude 0,3 mm. and. exposure 2 minutes. After euthanasia of hamsters of 48, 50, 66, 73 and. 90 days we revealed formation of endosteal bone reclaim in the area of perforating foramen on histological sections. Also in 5 animals after 3-15 seances of vibration in the zone of greater trochanter we registered periosteal osteogenesis on lateral surface of thigh-bones in their lower parts that caused local 2-3 times thickening of cortical plate in comparison with control segment of cortical plate.
190-192 495
Abstract
Reparation of tissues of purulent wounds at the Miliacylum treatment under conditions of infection was studied on 54 white mongrel male rats with simulated wound defects. Clinical and morphofunctional studies proved high efficiency of Miliacylum. in the treatment of purulent wounds.
193-197 400
Abstract
Aim of the research: to explore the model of esophagus and stomach chemical burn with modern chemical agents in the experiment on animals. The article presents the results of experimental research of chemical burn of the esophagus in Vistar rats. The burn of esophagus was conducted by modern chemical agents. As the result of the research the substances with «low» and «high» degree of aggressiveness were determined.
E. A. Tyukhay,
B. G. Pushkarev,
A. Yu. Safronov,
A. V. Kashevskiy,
I. V. Usoltsev,
O. A. Goldberg,
A. I. Plakhov,
N. P. Sudakov,
V. L. Tauson,
S. B. Nikiforov
198-200 416
Abstract
The article presents experimental results of electrochemical characteristics of bimetallic implants in experiment.
201-205 506
Abstract
Toxicological research of combined antitubercular preparation. «Protub-2®» that contains a pyridoxine hydrochloride (vitamin B). It was established, that introduction of pyridoxine hydrochloride in the structure of preparation «Protub-2®» allowed to reduce the majority of toxic effects caused by isoniazid and rifampicin that are parts of studied, preparation.
206-209 450
Abstract
The element structure of foodstuffs in infant schools is studied by the method of atomic emission spectrometry. Lowered content of macro- and microelements (first of all - Ca, Fe, P, Si) is typical for studied foodstuffs.
210-212 474
Abstract
The article determined that experimental acute pancreatitis in guinea-pigs was initially characterized by microcirculation disorders with further damage of parenchyma and stroma of the organ. Obtained, results confirm. primary vascular lesions with development ischemic symptom complex at the acute pancreatitis, that testifies to the necessity of further studies on the effectiveness of use of antioxidants at this pathology.
213-215 451
Abstract
The article presents the data on the appearance of significant changes in the condition of animals' organisms during quarterly daily intragastric administration, of polyvitaminic preparation of compound composition in a dose of 600 mg/kg and also on the lack of the changes at the administration in recommended, therapeutic dose. The preparation is not mutagenic.
A. G. Yushkov,
N. A. Shulgina,
A. A. Gushchina,
G. G. Yushkov,
M. M. Rasulov,
V. V. Benemanskiy,
M. M. Boon
216-219 439
Abstract
An. experimental research, of infusion solution of Metronidazole at single and repeated administration to the animals (rabbits) was carried out. Distinct signs of toxicity of the researched pattern. in the dose that is ten times higher than maximum, daily dose were determined. It concerns statistically reliably changed hematologic, biochemical and. electrophysiological indices that are typical for Metronidazole in particular. Only the fact of increase of content of creatinine in blood serum in 2 weeks after the administration, of the preparation should be registered but in this case it can be the signal to stop further administration, of the preparation.
REVIEWS OF LITERATURE
220-226 577
Abstract
The article is devoted to the questions of differential diagnostics in patients with chest pain at pre-hospital stage of medical care. On the basis of literary data the principle of construction of diagnostic algorithm by the physician for this group of patients is defined. Summarized literary data allowed to reveal the tendency of mutually burdening influence of different pathology, that is accompanied with chest pain, on the pathogenesis of basic disease. The principles of medical care for the patients with chest pain at pre-hospital stage are determined.
BRIEF
ISSN 2541-9420 (Print)
ISSN 2587-9596 (Online)
ISSN 2587-9596 (Online)
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