ROC-ANALYSIS OF NEUROIMMUNOLOGIC INDICES IN PATIENTS WITH CHRONIC PSYCHOGENIC URTICARIA
Abstract
Psychological stress connects with increased level of substance P, wherewith there may be interconnection between psychosomatic component and neuroimmunologic one in the chronic urticaria. Modern methods of findings statistical manipulation have been used in this work. Neuroimmunologic criteria of psychogenic urticaria were defined by the use of ROC-analysis. Substance P role in the pathogenesis of the disease have been indicated, correlation between substance P level and angiotensin converting enzyme (ACE) activity have been corroborated. Assessment of anxiety disorders level have been carried out.
References
1. Гомазков О.А. Физиологически активные пептиды: справ. рук. - М., 1995. - 142 с.
2. Крапивница и ангиоотек: Рос. национ. соглас. док.: рек. для практ. врачей. - М., 2007. -С. 8-9.
3. Орлова Е.А. Активность ферментов обмена нейропептидов при различных формах крапивницы: дис.... канд. мед. наук. - М., 2003. - 103 с.
4. Akcali C., Ozkur M., Erbagci Z. Association of insertion/deletion polymorphism of the angiotensinconverting enzyme gene with angio-oedema accompanying chronic urticaria but not chronic urticaria without angio-oedema or the autologous serum skin test response // J. Eur. Acad. Dermatol. Venereol. -2008. - Vol. 22, N 1. - Р. 83-86.
5. Foreman J.C. Substance P and Calcitonin Gene-Related Peptide effect on mast cells and in Human skin // International Archives of Allergy and Applied Immunology. - 1997. - Vol. 82, N 3/4. -P. 366-371.
6. Guilet, Garcia C., Guilet G. Urticare et psychisme: Du constat clinicue aux neuropeptides // J. Nat. Soc. Fr. Allergol. et immunol. Clin. - Toulouse, 1998. - P. 23-25.
7. Liezmann C., Klapp B., Peters E.M. Stress, atopy and allergy: A re-evaluation from a psychoneuroim-munologic persepective // Dermatoendocrinol. -2011. - Vol. 3, N 1. - Р. 37-40.
8. Panconesi E., Hautmann G. Psychophysiology of stress in dermatology. The psychobiologic pattern of psychosomatics // Dermatologic clinics. - 1996. -Vol. 14, N 3. - P. 399-421.
Review
For citations:
Orlova E.A. ROC-ANALYSIS OF NEUROIMMUNOLOGIC INDICES IN PATIENTS WITH CHRONIC PSYCHOGENIC URTICARIA. Acta Biomedica Scientifica. 2012;(3(2)):133-137. (In Russ.)
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