Assessment of the degree of activity of Crohn’s disease in patients using a specialized scale based on magnetic resonance enterography

G. M. Zhargalova; P. V. Seliverstov

doi:10.29413/ABS.2025-10.6.5

Assessment of the degree of activity of Crohn’s disease in patients using a specialized scale based on magnetic resonance enterography

G. M. Zhargalova, P. V. Seliverstov

https://doi.org/10.29413/ABS.2025-10.6.5

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Abstract

Background. Magnetic resonance enterography is increasingly being used to diagnose Crohn’s disease due to its non-invasiveness, absence of ionizing radiation, and high information content. Despite this, there is still no consensus in the international medical community regarding the use of inflammation indices during MR enterography.

The aim. The presented study examines the possibility of using a specialized scale based on magnetic resonance enterography data to assess the degree of disease activity in patients with Crohn’s disease.

Materials and methods. The analysis was conducted on a group of 40 patients with a confirmed diagnosis of Crohn’s disease, whose intestinal tract was evaluated according to the criteria of the specialized scale.

Results. During data processing, it turned out that 24 patients (60.0 %) had a score range of 0 to 7, which indicated remission, 10 (25.0 %) had a score range of 8 to 15 (minimal activity), and 6 (15.0 %) had a score range of 16 or more (severe clinical manifestations).

Conclusion. Thus, the scale we developed for assessing the activity of Crohn’s disease serves as an effective tool for standardizing diagnosis and monitoring patients’ conditions. This method provides an objective assessment of the level of inflammation and the course of the disease.

Keywords

Crohn’s disease, magnetic resonance enterography, MR indices of inflammatory activity

About the Authors

G. M. Zhargalova

Irkutsk Scientific Centre of Surgery and Traumatology; Irkutsk City Regional Oncological Clinic; Irkutsk State Medical Academy of Postgraduate Education – branch of the Russian Medical Academy of Postgraduate Education of the Ministry of Health of the Russian Federation
Russian Federation

Galina M. Zhargalova – Graduate Student, Irkutsk Scientific Centre of Surgery and Traumatology; Radiologist at the MRI Department, Irkutsk City Regional Oncological Clinic; assistant of the Department of Radiation and Clinical Laboratory, Irkutsk State Medical Academy of Postgraduate Education – branch of the Russian Medical Academy of Postgraduate Education of the Ministry of Health of the Russian Federation

Bortsov Revolyutsii str. 1, Irkutsk 664003;
Frunze str., 32, Irkutsk 664035:
Yubileyny Microdistrict, 100, Irkutsk, 664049

P. V. Seliverstov

Irkutsk Scientific Centre of Surgery and Traumatology
Russian Federation

Pavel V. Seliverstov – Dr. Sc. (Med.), Leading Research Officer, Head of the Department of Radiodiagostics of the Clinical Research Department of Neurosurgery

Bortsov Revolyutsii str. 1, Irkutsk 664003

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Review

For citations:

Zhargalova G.M., Seliverstov P.V. Assessment of the degree of activity of Crohn’s disease in patients using a specialized scale based on magnetic resonance enterography. Acta Biomedica Scientifica. 2025;10(6):37-45. (In Russ.) https://doi.org/10.29413/ABS.2025-10.6.5

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