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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2025-10.6.5</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-5734</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВНУТРЕННИЕ БОЛЕЗНИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INTERNAL DISEASES</subject></subj-group></article-categories><title-group><article-title>Оценка степени активности болезни Крона у пациентов с использованием специализированной шкалы на основе магнитно-резонансной энтерографии</article-title><trans-title-group xml:lang="en"><trans-title>Assessment of the degree of activity of Crohn’s disease in patients using a specialized scale based on magnetic resonance enterography</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3882-2208</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жаргалова</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhargalova</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жаргалова Галина Мункоевна – аспирант ФГБНУ «Иркутский научный центр хирургии и травматологии»; врач-рентгенолог кабинета МРТ ГБУЗ «Областной онкологический диспансер»; ассистент кафедры лучевой и клинической лаборатории Иркутской государственной академии последипломного образования – филиала ФГБОУ ДПО РМАНПО</p><p>664003, Иркутск, ул. Борцов Революции,1: 664032, г. Иркутск, ул. Фрунзе, д. 32; 664049, г. Иркутск, м/р Юбилейный, 100</p><p> </p></bio><bio xml:lang="en"><p>Galina M. Zhargalova – Graduate Student, Irkutsk Scientific Centre of Surgery and Traumatology; Radiologist at the MRI Department, Irkutsk City Regional Oncological Clinic; assistant of the Department of Radiation and Clinical Laboratory, Irkutsk State Medical Academy of Postgraduate Education – branch of the Russian Medical Academy of Postgraduate Education of the Ministry of Health of the Russian Federation </p><p>Bortsov Revolyutsii str. 1, Irkutsk 664003; Frunze str., 32, Irkutsk 664035: Yubileyny Microdistrict, 100, Irkutsk, 664049</p></bio><email xlink:type="simple">zhin.galina@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4050-9157</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селиверстов</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Seliverstov</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Селиверстов Павел Владимирович – доктор медицинских наук, ведущий научный сотрудник, заведующий отделением лучевой диагностики научно-клинического отдела нейрохирургии</p><p>664003, Иркутск, ул. Борцов Революции,1</p></bio><bio xml:lang="en"><p>Pavel V. Seliverstov – Dr. Sc. (Med.), Leading Research Officer, Head of the Department of Radiodiagostics of the Clinical Research Department of Neurosurgery </p><p>Bortsov Revolyutsii str. 1, Irkutsk 664003</p></bio><email xlink:type="simple">pavv2001@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Иркутский научный центр хирургии и травматологии»; &#13;
ГБУЗ «Областной онкологический диспансер»; &#13;
Иркутская государственная академия последипломного образования – филиал ФГБОУ ДПО РМАНПО Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk Scientific Centre of Surgery and Traumatology; &#13;
Irkutsk City Regional Oncological Clinic; &#13;
Irkutsk State Medical Academy of Postgraduate Education – branch of the Russian Medical Academy of Postgraduate Education of the Ministry of Health of the Russian Federation</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Иркутский научный центр хирургии и травматологии»</institution></aff><aff xml:lang="en"><institution>Irkutsk Scientific Centre of Surgery and Traumatology</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>13</day><month>01</month><year>2026</year></pub-date><volume>10</volume><issue>6</issue><fpage>37</fpage><lpage>45</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жаргалова Г.М., Селиверстов П.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Жаргалова Г.М., Селиверстов П.В.</copyright-holder><copyright-holder xml:lang="en">Zhargalova G.M., Seliverstov P.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/5734">https://www.actabiomedica.ru/jour/article/view/5734</self-uri><abstract><sec><title>Обоснование</title><p>Обоснование. Магнитно-резонансная энтерография (МР-энтерография) все шире используется для диагностики болезни Крона благодаря своей неинвазивности, отсутствию ионизирующего излучения и высокой информативности. Несмотря на это, в международном медицинском сообществе пока нет единого мнения относительно применения индексов воспаления при проведении МР-энтерографии.</p></sec><sec><title>Цель</title><p>Цель. В представленном исследовании изучается возможность применения специализированной шкалы, основанной на данных магнитно-резонансной энтерографии, для оценки степени активности заболевания у пациентов с болезнью Крона.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Анализ проведен на группе из 40 пациентов, на базе ГБУЗ «ООД» г. Иркутска с марта 2023 по май 2025, с подтвержденным диагнозом болезнь Крона, у которых оценивалось состояние кишечного тракта согласно критериям специализированной шкалы.</p></sec><sec><title>Результаты</title><p>Результаты. В ходе обработки данных оказалось, что у 24 пациентов (60,0 %) сумма баллов находилась в диапазоне от 0 до 7, что означало ремиссию, у 10 (25,0 %) – от 8 до 15 баллов (минимальная активность) и у 6 (15,0 %) – сумма баллов составляла от 16 и выше (ярко выраженные клинические проявления). </p></sec><sec><title>Заключение</title><p>Заключение. Таким образом, разработанная нами шкала для оценки активности болезни Крона служит эффективным инструментом стандартизации диагностики и мониторинга состояния пациентов. Применение данного метода обеспечивает объективную оценку уровня воспаления и динамики течения заболевания.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Magnetic resonance enterography is increasingly being used to diagnose Crohn’s disease due to its non-invasiveness, absence of ionizing radiation, and high information content. Despite this, there is still no consensus in the international medical community regarding the use of inflammation indices during MR enterography.</p></sec><sec><title>The aim</title><p>The aim. The presented study examines the possibility of using a specialized scale based on magnetic resonance enterography data to assess the degree of disease activity in patients with Crohn’s disease.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The analysis was conducted on a group of 40 patients with a confirmed diagnosis of Crohn’s disease, whose intestinal tract was evaluated according to the criteria of the specialized scale.</p></sec><sec><title>Results</title><p>Results. During data processing, it turned out that 24 patients (60.0 %) had a score range of 0 to 7, which indicated remission, 10 (25.0 %) had a score range of 8 to 15 (minimal activity), and 6 (15.0 %) had a score range of 16 or more (severe clinical manifestations).</p></sec><sec><title>Conclusion</title><p>Conclusion. Thus, the scale we developed for assessing the activity of Crohn’s disease serves as an effective tool for standardizing diagnosis and monitoring patients’ conditions. This method provides an objective assessment of the level of inflammation and the course of the disease.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь Крона</kwd><kwd>магнитно-резонансная энтерография</kwd><kwd>МР-индексы активности воспалительного процесса</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Crohn’s disease</kwd><kwd>magnetic resonance enterography</kwd><kwd>MR indices of inflammatory activity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cockburn E, Kamal S, Chan A, Rao V, Liu T, Huang JY, et al. Crohn’s disease: an update. Clin Med (Lond). 2023; 23(6): 549-557. doi: 10.7861/clinmed.2023-0493</mixed-citation><mixed-citation xml:lang="en">Cockburn E, Kamal S, Chan A, Rao V, Liu T, Huang JY, et al. Crohn’s disease: an update. 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