INFLUENCE of inhalation coal and rock dust on morphological changes of heart muscle (experimental research)
Abstract
Early stages of coal-dust exposure on laboratory animals do not cause morphological changes in heart muscle. Later periods (6—9 weeks of experiment) are accompanied on the one hand expressed compensatory-adaptive processes, on the other hand. - selective accumulation of lipofuscin in cardiomyocytes. Accumulation of lipofuscin is directly dependent on the duration of the adverse effects of the dust factor and. may be one of the main morphological markers of deep damage and cell death with prolonged exposure to coal and rock dust.
About the Authors
N. N. Mikhaylova
Research Institute of Complex Problems of Hygiene and Occupational Diseases SB RAMS
Russian Federation
Russian Federation
M. S. Bugaeva
State Institute of Physicians’ Training
Russian Federation
Russian Federation
O. I. Bondarev
State Institute of Physicians’ Training
Russian Federation
Russian Federation
References
1. Величковский Б.Т. Основные патогенетические механизмы профзаболеваний легких пылевой этиологии. Часть 1. От эксперимента к концепции // Мед. труда и пром. экология. — 1999. — № 8. — С. 20 — 27.
2. Еловская Л.Т. Модели экспериментального пневмокониоза и пылевого бронхита при ингаляционном воздействии // Гигиена и санитария. — 1986. — № 6. — С. 19 — 22.
3. Норейко С.Б., Чинякина Е.В., Пеленова И.В. Пневмокониозы // Фельдшер и акушерка. — 1990. — № 1. — С. 19 — 23.
Review
For citations:
Mikhaylova N.N., Bugaeva M.S., Bondarev O.I. INFLUENCE of inhalation coal and rock dust on morphological changes of heart muscle (experimental research). Acta Biomedica Scientifica. 2012;(5(2)):112-114. (In Russ.)
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