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INVESTIGATION OF LIPOPHILIC COMPOUNDS OF HERBS AND ROOTS OF CICHORIUM INTYBUS L

Abstract

Cichorium intybus L., a perennial herbaceous plant of Asteraceae family, is widely distributed in the flora of Russia. Aboveground and underground parts of this plant are used in scientific and traditional medicine as hypoglycemic, antioxidant, hepatoprotective remedy. In this experiment lipophilic fractions of the herb and roots of chicory by method of gas chromatography with mass spectrometry detection was investigated. 4s a result of the research in the grass we revealed the presence of 14 compounds: derivatives of higher fatty alcohols, vital, isophytol, 3,7,11,15-tetrameth- yl-l,6,10,14-hexametre-3-ol, heneicosane, polien, first identifiedD-Iimonene. In the roots of chicory ordinary identified 12 substances - derivatives oflinoleic acid, first identified a-gorunen, (1-veteranen, a-amyrin and betulin.

About the Authors

O. L. Saybel
All-Russian Research Institute of Medicinal and Aromatic Plants
Russian Federation


T. D. Dargayeva
All-Russian Research Institute of Medicinal and Aromatic Plants
Russian Federation


G. M. Latypova
Bashkir State Medical University
Russian Federation


E. G. Galkin
Ufa Institute of Chemitsty RAS
Russian Federation


References

1. Зенкевич И.Г. Аналитические параметры компонентов эфирных масел для их хроматографической и хромато-масс-спектрометрической идентификации. Кислородсодержащие производные моно- и сесквите- пеновых углеводородов // Растительные ресурсы. - 1997.-Т. 33, Вып. 1,-С. 16-26.

2. Лебедев A.T. Масс-спектрометрия в органической химии. - М.: БИНОМ, 2003. - 493 с.

3. Растительные ресурсы России. Дикорастущие цветковые растения, их компонентный состав и биологическая активность / отв. ред. А.Л. Будан- цев. - СПб.; М.: Товарищество научных изданий КМК, 2009. - Т. 5. Семейство Asteraceae (Compositae). Часть 1. Роды Achillea-Doronicum. - 513 с.

4. Регистр лекарственных средств России / под ред. Г.Л. Вышковского. - М., 2010. - 1368 с.

5. Толстикова Т.Г., Толстиков А.Г., Толстиков Г.А. Лекарства из растительных веществ / Российская академия наук. Сибирское отделение. Новосибирский институт органической химии им. Н.Н. Ворожцова. - Новосибирск: Гео, 2010. - 215 с.

6. Ahmed B, Al-Howiriny ТА, Siddiqui AB (2003). Antihepatotoxic activity of seeds ofCichorium intybus L. Journal ofEthnopharmacology, 87 (2-3), 237-240.

7. Ahmed OM, Hozayen WGM, Bastawy M, Harried MZ (2011). Biochemical effects ofCichorium intybus and Sonchus oleraceus infusions and esculetin on strepto- zotocin-induced diabetic albino rats. Journal of American Science, 7 (12), 1124-1137.

8. Hill HC, Read Rl, Robert-Lopes MT (1968). Mass-spectra and molecular structure. Part 1. Correlation Studies and metastable transitions./ Chem. Sol (1), 93-101.

9. Mehmood N, Zubair M, Rizwan K, Rasool N, Sha- hidb M, Ahmad VU (2012). Antioxidant, antimicrobial and phytochemical analysis of Cichorium intybus seeds extract and various organic fractions. Iranian Journal of Pharmaceutical Research, 11 (4), 1145-1151.


Review

For citations:


Saybel O.L., Dargayeva T.D., Latypova G.M., Galkin E.G. INVESTIGATION OF LIPOPHILIC COMPOUNDS OF HERBS AND ROOTS OF CICHORIUM INTYBUS L. Acta Biomedica Scientifica. 2015;(5):72-74. (In Russ.)

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ISSN 2541-9420 (Print)
ISSN 2587-9596 (Online)