AGED FEATURES OF ANTIOXIDANT PROTECTION UNDER COXIELLOSIS

Abstract

The results of the clinical examination and supervision of 62 patients under average-severe course of coxiellosis at the age of 17-74: the first group (32 persons) - patients younger than 50, the second group (30 persons) -patients older than 50 are presented here. Catalase and ceruloplasmin have been defined in the blood serum of the patients with coxiellosis in the disease dynamics. Clinical evidences of coxiellosis: hyperaemia of the pharynx, shivering, myalgy, weakness, scleroconjunctivitis and. arthralgy have been seen longer in the patients older than 50. Catalase and. ceruloplasmin. content depended on the period of the disease and the patients age. At age first week of the disease there noted decreasing of the сatalase levels in 80 % of the patients younger than 50; but in 100 % of the patients older than 50 increasing was noted. At the second week of the disease most of the patients, regardless of their age, had. decreased the levels of catalase. Increase of the levels of ceruloplasmine has been noted the elder aged group. At the third week of the disease at the background of ceasing of clinical evidences of the disease most patients with coxiellosis, independent on age, had. increased content of the studied indices, which shows the compensatory activation of the antioxidant protection.