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FORMATION OF RESPONSE OF RATS ORGANISM ON SINGLE INFLUENCE OF TERIZIDONE - 250 MG + PYRIDOXINE HYDROCHLORIDE - 10 MG

Abstract

The article presents the materials of experimental study of Terizidone in combination with pyridoxine hydrochloride in conditions of single peroral influence on animals in different doses with a view to reveal response of an organism for using in the evaluation of general toxic action of an advanced antituberculous preparation.

About the Authors

K. A. Badenikova
Angarsk State Technical Academy
Russian Federation


G. G. Yushkov
Angarsk State Technical Academy
Russian Federation


A. A. Gushchina
Angarsk State Technical Academy
Russian Federation


V. V. Benemanskiy
Angarsk State Technical Academy
Russian Federation


A. S. Gushchin
Public Corporation «Farmasintez», Irkutsk
Russian Federation


References

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2. Лабораторные методы в клинике / Под ред. В.В.Меньшикова. - М.: Медицина, 1987. -С. 106 - 125.

3. Руководство по экспериментальному (доклиническому) изучению новых фармакологических веществ. - М.: Ремедиум, 2000. - 398 с.

4. American hospital formulary service - drug information 96 / Ed. G.K. McEvoy. - Bethesda MO: American Society of Health-System pharmacists Inc., 1996. - P. 404.

5. Strata A. Clinical pharmacology of Terizidone // Lotta Tuberc. - 1971. - Vol. 41 (3). -P. 367 - 368.

6. Yasumitsu Т., Takao T., Kakimoto Y. Inhibition of metabolism of beta-alanine and beta-aminoisobutyric acid by D-cycloserine // Biochem. Pharmacol. - 1976. - Vol. 25, N 3. - P. 253 - 258.


Review

For citations:


Badenikova K.A., Yushkov G.G., Gushchina A.A., Benemanskiy V.V., Gushchin A.S. FORMATION OF RESPONSE OF RATS ORGANISM ON SINGLE INFLUENCE OF TERIZIDONE - 250 MG + PYRIDOXINE HYDROCHLORIDE - 10 MG. Acta Biomedica Scientifica. 2012;(4(2)):163-166. (In Russ.)

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ISSN 2541-9420 (Print)
ISSN 2587-9596 (Online)