ANTIBODIES TO BENZO[A]PYRENE IN SERUM OF PATIENTS WITH NON-SMALL CELL LUNG CANCER
Abstract
The features of immune response to chemical carcinogen benzo[a]pyrene (Bp) at the patients with non-small cell lung cancer (NSCLC) are investigated. The isotypical distinctions in formation of antibodies (Ab) to Bp at the men with NSCLC in comparison with healthy are revealed. There were more often observed the high levels of IgG Ab-Bp at the men with NSCLC. Thus risk of occurrence NSCLC grows almost in 2 times at high levels of Ab-Bp of a class G.
About the Authors
E. G. Polenok
Institute of Human Ecology SB RAS
Russian Federation
Russian Federation
T. P. Anosova
Institute of Human Ecology SB RAS
Russian Federation
Russian Federation
M. P. Anosov
Institute of Human Ecology SB RAS
Russian Federation
Russian Federation
K. S. Krasilnikova
Institute of Human Ecology SB RAS
Russian Federation
Russian Federation
E. A. Gurov
Institute of Human Ecology SB RAS
Russian Federation
Russian Federation
V. A. Titov
Kemerovo Regional clinical oncology hospital
Russian Federation
Russian Federation
N. E. Verzhbitskaja
Kemerovo Pathologoanatomic bureau
Russian Federation
Russian Federation
I. A. Vafin
Kemerovo Regional centre of blood
Russian Federation
Russian Federation
S. E. Ragozhina
Institute of Human Ecology SB RAS
Russian Federation
Russian Federation
A. N. Glushkov
Institute of Human Ecology SB RAS
Russian Federation
Russian Federation
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Review
For citations:
Polenok E.G., Anosova T.P., Anosov M.P., Krasilnikova K.S., Gurov E.A., Titov V.A., Verzhbitskaja N.E., Vafin I.A., Ragozhina S.E., Glushkov A.N. ANTIBODIES TO BENZO[A]PYRENE IN SERUM OF PATIENTS WITH NON-SMALL CELL LUNG CANCER. Acta Biomedica Scientifica. 2012;(3(2)):151-154. (In Russ.)
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