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GROWTH OF BIOLOGICAL MARKERS OF AGING AND ALLOSTASIS IN VETERANS OF THE AFGHAN WAR CONFLICT WITH EARLY FORMS OF CHRONIC BRAIN ISCHEMIA

Abstract

We investigated the rate of biological aging, the levels of stress hormones and regulatory cytokines in Afghan war veterans and civilians with early forms of chronic brain ischemia. The study established acceleration of aging according to biological age indicators, earlier clinical onset of early forms of chronic cerebrovascular diseases associated with the processes of posttraumatic disregulation of cerebral and systemic vascular tone, the accumulation of "allostatic load” in the form of hypercortisolemia, growth regulator and angiogenic cytokines in veterans of the Afghan conflict.

About the Authors

D. Sh. Altman
Chelyabinsk Regional Clinical Therapeutic Hospital For War Veterans; Chelyabinsk State Medical Academy
Russian Federation


E. V. Davydova
Chelyabinsk Regional Clinical Therapeutic Hospital For War Veterans; Chelyabinsk State Medical Academy
Russian Federation


N. G. Kochetkova
Chelyabinsk Regional Clinical Therapeutic Hospital For War Veterans
Russian Federation


A. V. Zurochka
Institute of Immunology and Physiology
Russian Federation


References

1. Мякотных И.С., Оранский И.Е., Мохова Е.Т. Проблемы старения. — Екатеринбург, 1999. — 324 с.

2. Пшенникова М.Г. Феномен стресса, эмоциональный стресс и его роль в патологии // Патол. физиология и эксперимент. мед. — 2001. — № 2. — С. 26 — 40.

3. Шмидт Е.В. Классификация сосудистых поражений головного и спинного мозга // Журн. неврологии и психиатрии им. С.С. Корсакова. — 1985. — № 9. — С. 1281 — 1288.

4. Felten D., Maida M.E. Psychoneuroimmunology // in book: Encylopedia of the human brain // Ed.-in- cnief V.S. Ramachandran. — 2002. — Vol. 4. — P. 103—127.

5. McEwen B., Lupien S. Stress: hormonal and neural aspects // in book: Encyclopedia of the human brain // Ed.-in- cnief V.S. Ramachandran. — 2002. — Vol. 4. — P. 463 — 474.

6. Stampfer H.G. «Negative symptoms»: a cumulative trauma stress disorder // Aust. N. Zeal. J. Psychiatry. — 1990. — Vol. 24, № 4. — P. 516 — 528.


Review

For citations:


Altman D.Sh., Davydova E.V., Kochetkova N.G., Zurochka A.V. GROWTH OF BIOLOGICAL MARKERS OF AGING AND ALLOSTASIS IN VETERANS OF THE AFGHAN WAR CONFLICT WITH EARLY FORMS OF CHRONIC BRAIN ISCHEMIA. Acta Biomedica Scientifica. 2012;(3(2)):15-18. (In Russ.)

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ISSN 2541-9420 (Print)
ISSN 2587-9596 (Online)