BIOLOGICAL EFFECTS OF THE NEW SILVER-CONTAINING POLYMER NANOCOMPOSITE
M. A. Novikov,
E. A. Titov,
V. A. Vokina,
N. L. Yakimova,
L. M. Sosedova,
S. A. Korzhova,
A. S. Pozdnyakov,
A. I. Emelyanov,
O. A. Proydakova,
T. G. Ermakova,
G. F. Prozorova
Abstract
In the materials there are presented, results of the synthesis and biological testing of the new nanocomposite which, contains silver nanoparticles incapsulated. in the synthetic polymer poly-1-vinyl-1,2,4-triazole. The synthesis method, of silvercontaining polymere nanocomposite is shown. With the use of modern equipment evidence of the nanocomposite with the size of 2-10 nm silver production, are substinated. It was revealed, that the new nanocomposite causes slight changes in the tissue structure of experimental animals internal organs and biochemical shift that is characteristic for the compensatory-adaptive reactions development. There are presented, the results of the silver nanoparticles distribution, mainly in the kidney and. liver tissue.
About the Authors
M. A. Novikov
Institute of Occupational Health and Human Ecology ESSC HE SB RAMS, Angarsk
Russian Federation
E. A. Titov
Institute of Occupational Health and Human Ecology ESSC HE SB RAMS, Angarsk
Russian Federation
V. A. Vokina
Institute of Occupational Health and Human Ecology ESSC HE SB RAMS, Angarsk
Russian Federation
N. L. Yakimova
Institute of Occupational Health and Human Ecology ESSC HE SB RAMS, Angarsk
Russian Federation
L. M. Sosedova
Institute of Occupational Health and Human Ecology ESSC HE SB RAMS, Angarsk
Russian Federation
S. A. Korzhova
A.E. Favorsky Irkutsk Institute of Chemistry SB RAS, Irkutsk
Russian Federation
A. S. Pozdnyakov
A.E. Favorsky Irkutsk Institute of Chemistry SB RAS, Irkutsk
Russian Federation
A. I. Emelyanov
A.E. Favorsky Irkutsk Institute of Chemistry SB RAS, Irkutsk
Russian Federation
O. A. Proydakova
Institute of Geochemistry SB RAS, Irkutsk
Russian Federation
T. G. Ermakova
A.E. Favorsky Irkutsk Institute of Chemistry SB RAS, Irkutsk
Russian Federation
G. F. Prozorova
A.E. Favorsky Irkutsk Institute of Chemistry SB RAS, Irkutsk
Russian Federation
References
1. Kobayasi N. Vvedenie v nanotekhnologiyu. -M.: Binom. Laboratoriya znanii, 2007. - S. 34-40.
2. Prozorova G.F., Korzhova S.A., Kon'kova T.V., Ermakova T.G. i dr. Osobennosti formirovaniya nanochastits serebra v polimernoi matritse // DAN. - 2011. - T. 437, № 1. - S. 50-52.
3. Kagan V.E., Bayir H., Shvedova A.A. Nanomedicine and nanotoxicology: two sides of the same coin // Nanomedicine: nanotechnology, biology and medicine. - 2005. - Vol. 1. - P. 313-316.
4. Oberdorster G., Oberdorster E., Oberdorster J. Nanotoxicology: Am Emerging Discipline Evolving from Studies of Ultrafine Particles // Environmental Health Perspectives. - 2005. - N 7 (13). - P. 823-839.
For citations:
Novikov M.A.,
Titov E.A.,
Vokina V.A.,
Yakimova N.L.,
Sosedova L.M.,
Korzhova S.A.,
Pozdnyakov A.S.,
Emelyanov A.I.,
Proydakova O.A.,
Ermakova T.G.,
Prozorova G.F.
BIOLOGICAL EFFECTS OF THE NEW SILVER-CONTAINING POLYMER NANOCOMPOSITE. Acta Biomedica Scientifica. 2012;(2(2)):121-125.
(In Russ.)
Views:
395
Email this article 
