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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-830</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ В БИОЛОГИИ И МЕДИЦИНЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL RESEARCHES IN BIOLOGY AND MEDICINE</subject></subj-group></article-categories><title-group><article-title>БИОЛОГИЧЕСКИЕ ЭФФЕКТЫ НОВОГО СЕРЕБРОСОДЕРЖАЩЕГО ПОЛИМЕРНОГО НАН0К0МП0ЗИТА</article-title><trans-title-group xml:lang="en"><trans-title>BIOLOGICAL EFFECTS OF THE NEW SILVER-CONTAINING POLYMER NANOCOMPOSITE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новиков</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Novikov</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">novik-imt@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Титов</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Titov</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">g57097@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вокина</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vokina</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">wokina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Якимова</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakimova</surname><given-names>N. L.</given-names></name></name-alternatives><email xlink:type="simple">ynl-77@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соседова</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Sosedova</surname><given-names>L. M.</given-names></name></name-alternatives><email xlink:type="simple">imt@irmail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коржова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korzhova</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">korzhova@irioch.irk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поздняков</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pozdnyakov</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">pozdnyakov@irioch.irk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Емельянов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Emelyanov</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">emelyanov@irioch.irk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пройдакова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Proydakova</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">proyd@igc.irk.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермакова</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermakova</surname><given-names>T. G.</given-names></name></name-alternatives><email xlink:type="simple">ermakova@irioch.irk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прозорова</surname><given-names>Г. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Prozorova</surname><given-names>G. F.</given-names></name></name-alternatives><email xlink:type="simple">prozorova@irioch.irk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ангарский филиал ФГБУ «ВСНЦ ЭЧ» СО РАМН</institution></aff><aff xml:lang="en"><institution>Institute of Occupational Health and Human Ecology ESSC HE SB RAMS, Angarsk</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Иркутский институт химии им. А.Е. Фаворского СО РАН</institution></aff><aff xml:lang="en"><institution>A.E. Favorsky Irkutsk Institute of Chemistry SB RAS, Irkutsk</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Институт геохимии им. А.П. Виноградова СО РАН</institution></aff><aff xml:lang="en"><institution>Institute of Geochemistry SB RAS, Irkutsk</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2012</year></pub-date><volume>0</volume><issue>2(2)</issue><fpage>121</fpage><lpage>125</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Новиков М.А., Титов Е.А., Вокина В.А., Якимова Н.Л., Соседова Л.М., Коржова С.А., Поздняков А.С., Емельянов А.И., Пройдакова О.А., Ермакова Т.Г., Прозорова Г.Ф., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Новиков М.А., Титов Е.А., Вокина В.А., Якимова Н.Л., Соседова Л.М., Коржова С.А., Поздняков А.С., Емельянов А.И., Пройдакова О.А., Ермакова Т.Г., Прозорова Г.Ф.</copyright-holder><copyright-holder xml:lang="en">Novikov M.A., Titov E.A., Vokina V.A., Yakimova N.L., Sosedova L.M., Korzhova S.A., Pozdnyakov A.S., Emelyanov A.I., Proydakova O.A., Ermakova T.G., Prozorova G.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/830">https://www.actabiomedica.ru/jour/article/view/830</self-uri><abstract><p>В материалах представлены результаты синтеза и биологического испытания нового нанокомпозита, содержащего наночастицы, серебра, инкапсулированные в синтетический полимер — поли-1-винил- 1,2,4-триазол. Показана методика синтеза водорастворимого серебросодержащего полимерного нанокомпозита. С использованием, комплекса современных методов анализа установлено, что полученный нанокомпозит, состоит, из наночастиц серебра размерами 2—10 нм. стабилизированных полимерной матрицей. Выявлено, что новый нанокомпозит, вызывает, незначительные изменения в структуре тканей внутренних органов экспериментальных животных и. биохимические сдвиги, характерные для. развития, компенсаторно-приспособительных реакций. Представлены, результаты распределения, наночастиц серебра преимущественно в ткани почек и. печени.</p></abstract><trans-abstract xml:lang="en"><p>In the materials there are presented, results of the synthesis and biological testing of the new nanocomposite which, contains silver nanoparticles incapsulated. in the synthetic polymer poly-1-vinyl-1,2,4-triazole. The synthesis method, of silvercontaining polymere nanocomposite is shown. With the use of modern equipment evidence of the nanocomposite with the size of 2-10 nm silver production, are substinated. It was revealed, that the new nanocomposite causes slight changes in the tissue structure of experimental animals internal organs and biochemical shift that is characteristic for the compensatory-adaptive reactions development. There are presented, the results of the silver nanoparticles distribution, mainly in the kidney and. liver tissue.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нанокомпозит</kwd><kwd>поли-1-винил-1</kwd><kwd>наносеребро</kwd><kwd>экспериментальные исследования</kwd><kwd>белые крысы</kwd><kwd>морфология тканей органов</kwd></kwd-group><kwd-group xml:lang="en"><kwd>2</kwd><kwd>4-триазол</kwd><kwd>nanocomposite</kwd><kwd>the polymer poly-1-vinyl-1</kwd><kwd>2</kwd><kwd>4-triazole</kwd><kwd>nanosilver</kwd><kwd>experimental studies</kwd><kwd>white rats</kwd><kwd>the morphology of organ tissues</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кобаяси Н. Введение в нанотехнологию. -М.: Бином. Лаборатория знаний, 2007. - С. 34-40.</mixed-citation><mixed-citation xml:lang="en">Кобаяси Н. Введение в нанотехнологию. -М.: Бином. 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