SYNTHESIS OF NOVEL UNSATURATED ORGANOTELLURIUM COMPOUNDS WITH POTENTIAL BIOLOGICAL ACTIVITY
Abstract
Efficient synthetic approaches to novel organotellurium. compounds with potential biologically activity were elaborated, based, on acetylenes and tellurium, tetrahalid.es.
About the Authors
M. V. Musalova
A.E. Favorsky Irkutsk Institute of Chemistry SB RAS, Irkutsk
Russian Federation
Russian Federation
V. A. Potapov
A.E. Favorsky Irkutsk Institute of Chemistry SB RAS, Irkutsk
Russian Federation
Russian Federation
S. V. Amosova
A.E. Favorsky Irkutsk Institute of Chemistry SB RAS, Irkutsk
Russian Federation
Russian Federation
References
1. Потапов В.А., Мусалова М.В., Амосова С.В. Синтез Е-2-хлорвинилтеллуртрихлорида и Е,Е-бис(2-хлорвинил)дителлурида // Изв. АН. Сер. хим. - 2012. - C. 201 -202.
2. Реакция тетрахлорида теллура с ацетиленом / В.А. Потапов, М.В. Мусалов, М.В. Мусалова, С.В. Амосова // Изв. АН. Сер. хим. — 2009. — C. 2327-2328.
3. A new immunomodulating compound (AS-101) with potential therapeutic application / B. Sredni, R.R. Caspi, A. Klein [et al.] // Nature. - 1987. -Vol. 330. - P. 173-176.
4. A novel organotellurium compound (RT-01) as a new antileishmanial agent / C.B.C. Lima, W.W. Arrais-Silva, R.L.O.R. Cunha, S. Giorgio // Korean J. Parasitol. - 2009. - Vol. 47. - P. 213-218.
5. Antioxidative properties of organotellurium compounds in cell systems / E. Wieslander, L. Engman, E. Svensjo [et al.] // Biochem. Pharmacol. - 1998. -Vol. 55. - P. 573-584.
6. Bcl-2 expression and apoptosis induction in human HL60 leukaemic cells treated with a novel organotellurium (IV) compound RT-04 / T.S. Abondanza, C.R. Oliveira, C.M. Barbosa [et al.] // Food Chem. Toxicol. - 2008. - Vol. 46. -P. 2540-2545.
7. Binding of tellurium to hepatocellular selenoproteins during incubation with inorganic tellurite: consequences for the activity of selenium-dependent glutathione peroxidase / P. Garberg, L. Engman, V. Tolmachev [et al.] // Int. J. Biochem. Cell. Biol. - 1999. - Vol. 31. - P. 291 -301.
8. Chasteen T.G., Bentley R. Biomethylation of selenium and tellurium: microorganisms and plants // Chem. Rev. - 2003. - Vol. 103. - P. 1-25.
9. Cytometric determination of novel organotellurium compound toxicity in a promyelocytic (HL-60) cell line / B.L. Sailer, N. Liles, S. Dickerson, T.G. Chasteen // Arch. Toxicol. 2003. - Vol. 77. -P. 30-36.
10. Nogueira C.W., Zeni G., Rocha J.B.T. Organoselenium and organotellurium compounds: toxicology and pharmacology // Chem. Rev. -2004. - Vol. 104. - P. 6255-6285.
11. Petragnani N., Stefani H.A. Tellurium in Organic Synthesis. - London: Academic Press, 2007. - 372 p.
12. Tellurium-based cysteine protease inhibitors: evaluation of novel organotellurium (IV) compounds as inhibitors of human cathepsin B / R.L. Cunha, M.E. Urano, J.R. Chagas [et al.] // Bioorg. Med. Chem. Lett. - 2005. - Vol. 15. - P. 755-760.
13. The novel tellurium immunomodulator AS101 inhibits interleukin-10 production and p38 MAPK expression in atopic dermatitis / D. Sredni-Kenigsbuch, M. Shohat, B. Shohat [et al.] // J. Dermatol. Sci. 2008. - Vol. 50. - P. 232-235.
14. The protective role of the immunomodulator AS101 against chemotherapy-induced alopecia: studies on human and animal models / B. Sredni, R.H. Xu, M. Albeck [et al.] // Int. J. Cancer. - 1996. -Vol. 65. - P. 97-103.
15. Vinylic tellurides: from preparation to their applicability in organic synthesis / G. Zeni, D.S. Ludtke, R.B. Panatieri, A.L. Braga // Chem. Rev. - 2006. - Vol. 106. - P. 1032-1076.
Review
For citations:
Musalova M.V., Potapov V.A., Amosova S.V. SYNTHESIS OF NOVEL UNSATURATED ORGANOTELLURIUM COMPOUNDS WITH POTENTIAL BIOLOGICAL ACTIVITY. Acta Biomedica Scientifica. 2012;(2(2)):117-120. (In Russ.)
Views:
375
.png)
Email this article 
