INFLUENCE OF TRANEXAMIC ACID ON HEMORRHAGE AT THE REVISION HIP REPLACEMENT SURGERY
Abstract
The article describes the results of investigation of the influence of tranexamic acid, on hemostasis system, at the revision hip replacement surgery. Correlation of changes in hemostasis system, and hemorrhage in intra-and postoperative periods, frequency of hemotransfusion, at the stages of the operation and in postoperative period, were evaluated. Use of tranexamic acid, at the revision hip replacement surgeries reduces perioperative hemorrhage.
About the Authors
A. M. Ageenko
Novosibirsk Research Institute of Traumatology and Orthopedics
Russian Federation
Russian Federation
A. V. Zhukov
Novosibirsk Research Institute of Traumatology and Orthopedics
Russian Federation
Russian Federation
T. I. Pospelova
Novosibirsk Research Institute of Traumatology and Orthopedics
Russian Federation
Russian Federation
G. G. Guschevarova
Novosibirsk Research Institute of Traumatology and Orthopedics
Russian Federation
Russian Federation
S. A. Mikheeva
Novosibirsk Research Institute of Traumatology and Orthopedics
Russian Federation
Russian Federation
References
1. Прохоренко В.М. Первичное и ревизионное эндопротезирование тазобедренного сустава. — Новосибирск, 2007. — 345 с.
2. Сезонные колебания величины интраоперационной кровопотери при реэндопротезировании тазобедренного сустава / А.С. Аврунин, Н.В. Корнилов, В.М. Кустов, А.Н. Фролов // Вестн. хирургии им. И.И. Грекова. — М., 2003. — Т. 162, N 1. - С. 49-51.
3. Benoni G. Tranexamic acid reduces the blood loss in knee arthroplasty — if it's administered at the right time // Lakartidningen. — 1999. — Vol. 96 (24). — P. 2967 — 2969.
4. Brown S., Thwaites B.K., Morgan P.D. Tranexamic acid is effective in decreasing postoperative bleeding and transfusions in primary coronary arterybypass operations: A double-blind, randomized, placebo-controlled trial // Robert Anesth. Analg. — 1997. — Vol. 85. — P. 963 — 970.
5. Callaghan J.J., O'Rourke M.R., Liu S.S. Blood management: issues and options // J. Arthroplasty. — 2005. — Vol. 20 (4), Suppl. 2. — P. 51—54.
6. Claeys M.A., Vermeersch N., Haentjens P. Reduction of blood loss with tranexamic acid in primary total hip replacement surgery // Acta. Chir. Belg. — 2007. Vol. 107 (4). — P. 397 — 401.
7. Ekback G., Axelsson K., Ryttberg L. Tranexamic acid reduces blood loss in total hip replacement surgery // Anesth. Analg. — 2000. — Vol. 91, N 5. — P. 1124—1130.
8. Hoylaerts M., Lijnen H.R., Collen D. Studies on the mechanism of the antifibrinolytic action of tranexamicacid // Biochim. Biophys. Acta. — 1981. — Vol. 673. — P. 75 — 85.
9. Noordin S., Waters T.S. Tranexamic acid reduces allogenic transfusion in revision hip arthroplasty // Clin. Orthop. Relat. Res. — 2010. — Vol. 469, N 2. — P. 541 —546.
10. One intraoperative dose of tranexamic acid for patients having primary hip or knee arthroplasty / F.E. Ralley, D. Berta, V. Binns, J. Howard [et al.] // The Association of Bone and Joint Surgeons. — 2009. — Vol. 468, N 7. — P. 1905 — 1911.
11. Seven to 10 years follow-up of an anatomic hip prosthesis. An international study / A. Herrera, V. Canales, J. Anderson et al. // Clin. Orthop. — 2004. — 423. — P. 129—137.
12. The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement / K. Rajesparan, L.C. Biant, M. Ahmad, R.E. Field // Bone Joint Surg. Br. — 2009. — Vol. 91 (6). — P. 776 — 783.
13. Tranexamic acid administration after cardiac surgery: a prospective, randomized, double-blind, placebo-controlled study / V. Casati, F. Bellotti, C. Gerli [et al.] // Anesthesiology. — 2001. — Vol. 94. — P. 8—14.
14. Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty / G. Benoni, S. Lethagen, P. Nilsson, H. Fredin // Acta Orthop. Scand. — 2000. — Vol. 71. — P. 250 — 254.
15. Tranexamic acid reduces postoperative blood losses associated with elective total hip replacement / P. Duquenne, L. Lhoest, W. Henkes, F. De Sart // J. Bone Joint Surg. Br. — 1999. — Vol. 81, Suppl. II (Abstr. 489). — P. 233 — 234.
Review
For citations:
Ageenko A.M., Zhukov A.V., Pospelova T.I., Guschevarova G.G., Mikheeva S.A. INFLUENCE OF TRANEXAMIC ACID ON HEMORRHAGE AT THE REVISION HIP REPLACEMENT SURGERY. Acta Biomedica Scientifica. 2012;(2(1)):9-12. (In Russ.)
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