Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A
Abstract
The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products reacting with thiobarbituric acid (141,7%) with a simultaneous decrease in the content of diene conjugates (69,4%), compared with the same indicators in the control group. The level of antioxidant protection in women in main group unlike the control was characterized by a decrease in total antioxidant activity (25,2%), by the inhibition of the activity of superoxide dismutase (29,1%), by decreasing the concentration of a-tocopherol (42,6%) on the background of increase of retinol level (184,6%). In general, the combination of prooxidant and antioxidant factors at HAV can be considered as a condition of oxidative stress (p < 0,05).
About the Authors
B. Ya. Vlasov
Scientific Centre for the Family Health and Human Reproduction Problems
Russian Federation
Russian Federation
M. A. Rashidova
Scientific Centre for the Family Health and Human Reproduction Problems
Russian Federation
Russian Federation
L. F. Sholokhov
Scientific Centre for the Family Health and Human Reproduction Problems
Russian Federation
Russian Federation
O. A. Vanteeva
Scientific Centre for the Family Health and Human Reproduction Problems
Russian Federation
Russian Federation
E. L. Chudinova
Scientific Centre for the Family Health and Human Reproduction Problems
Russian Federation
Russian Federation
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Review
For citations:
Vlasov B.Ya., Rashidova M.A., Sholokhov L.F., Vanteeva O.A., Chudinova E.L. Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A. Acta Biomedica Scientifica. 2015;(1):7-10.
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