Gender peculiarities of gastroesophageal reflux disease
Abstract
We studied gender-specific clinical manifestations and risk factors for gastroesophageal reflux disease (GERD) in the urban population of Ulan-Ude. The study included 352 patients with GERD. It was found that in both sexes prevailed not erosive reflux disease. It was detected in 64,2% of men and in 88% of women (p = 0,005). Men significantly more often had severe forms of the disease: erosive esophagitis - 19,8% more often than in women (p = 0,04), in 2,9% of men we revealed esophageal ulcers, in 1,1% - Barrett esophagus, while the in women didn't have these forms of the disease. Daily repeated heartburn was found in women twice more often than in men. Average grade of GERD-Q questionnaire for women was also significantly higher than for men by 19% (p = 0,04). Women had higher levels of anxiety and depression (average grade on BDI was higher by 29% than in men). Men had significantly more frequently such risk factors as smoking, alcohol intake and women more often had diabetes, hypertension and coronary heart disease.
About the Authors
T. Y. Spasova
Buryat State University
Russian Federation
Russian Federation
E. V. Grigorieva
Irkutsk State Medical Academy of Continuing Education
Russian Federation
Russian Federation
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For citations:
Spasova T.Y., Grigorieva E.V. Gender peculiarities of gastroesophageal reflux disease. Acta Biomedica Scientifica. 2015;(2):38-41. (In Russ.)
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