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ACTIVITY OF AMINOLEVULINATE SYNTHASE OF BONE MARROW AND LIVER OF NEWBORN AUGUST AND WISTAR RATS AFTER ACUTE POSTNATAL HYPOXIA

Abstract

Newborn Wistar and August rats (20 rats in each experimental group) were exposed to acute postnatal hypoxic hypoxia (by the mixture of 95% nitrogen and 5% oxygen). Determination of activity of aminolevulinate synthase (ALA-synthase) in bone marrow and liver were in control group, and on the 1st and 3rd days of life (in liver - only on the 3rd day). Infant rats of various lines differed by the response of an organism to hypoxic exposure that confirms its genetic predetermination. Activities of ALA-synthase in bone marrow and liver were reciprocal both in normal development and after hypoxia. K

About the Authors

L. I. Kolesnikova
Scientific Centre for Family Health and Human Reproduction Problems SB RAMS
Russian Federation


A. S. Popova
Municipal Clinical Hospital N 6
Russian Federation


L. I. Krupitskaya
South-Ural State Medical University
Russian Federation


A. I. Sinitskiy
South-Ural State Medical University
Russian Federation


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For citations:


Kolesnikova L.I., Popova A.S., Krupitskaya L.I., Sinitskiy A.I. ACTIVITY OF AMINOLEVULINATE SYNTHASE OF BONE MARROW AND LIVER OF NEWBORN AUGUST AND WISTAR RATS AFTER ACUTE POSTNATAL HYPOXIA. Acta Biomedica Scientifica. 2014;(6):60-62. (In Russ.)

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ISSN 2541-9420 (Print)
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