Anticonvulsant effect of dry extract from the roots of Paeonia anomala L

Abstract

The aim of the research was to define anticonvulsive effect of the dry extract from Paeonia anomala L. and comparison with its liquid dosage form. Convulsions in male SVA rats weighing 18-20 g were induced by single dosing of pentylenetetrazol, strychnine nitrate and thiosemicarbazide in a dose of DL_1gg Animals of the trial group had single intragastric introduction of peony extract solution in a dose of 150 mg/kg 1 hour before the introduction of above mentioned medicines. As the result it was found that dry extract of Paeonia anomala L. had evident anticonvulsant effect.