Methodology of experimental researches in surgery (lecture)

Abstract

Experimental simulation of pathological processes is of greatest importance for perception of essence of various kinds of surgical pathology, for deciphering etiology and pathogenesis of disorders and finding possible ways of their management. The goal of an experimental research is systematization, strengthening and extension of theoretical and practical skills and experiences, and practicing their application in solving scientific problems. To perform an experiment one needs to have research skills, knowledge of modern techniques of setting up an experiment, evaluation and interpretation of its results, to be able to make public speeches at conferences, to present the case in the form of an article or an abstract, to work with scientific references, to compose priority documents (patents and innovation proposals). Methodology is an algorithm of goal search, set of techniques, methods, measures and principles of goal achievement. Peculiar feature of experimental researches involving laboratory animals is high moral responsibility, in particular connected with humane treatment of animals, and this responsibility falls both on the performer and on his research adviser.