Influence of thyrotropic herbal remedy on vascular endothelium and thyroid gland structure in experimental hypothyroidism
Abstract
The work presents evaluation of influence of plant preparation «Thyreoton-forte» on endothelium of vessels and morphological structure of thyroid gland in experimental hypothyreosis. Experimental hypothyreosis in rats was induced by administration of mercazolilum (10 mg/kg, intragastric introduction) during 28 days. The course administration of «Thyreoton-forte» (50,100 mg/kg, intragastric introduction) decreases the number of circulating endothelial cells (p < 0,05) and normalizes the structure of thyroid gland. Pharmacological effect of «Thyreoton-forte» is provided by protective influence in vascular endothelium and positive action on thyroid gland.
About the Authors
S. M. Gulyayev
Institute of General and Experimental Biology SB RAS
Russian Federation
Russian Federation
E. V. Arkhipova
Buryat State University
Russian Federation
Russian Federation
S. V. Lemza
Institute of General and Experimental Biology SB RAS
Russian Federation
Russian Federation
N. A. Khamayeva
Institute of General and Experimental Biology SB RAS
Russian Federation
Russian Federation
S. M. Nikolayev
Institute of General and Experimental Biology SB RAS; Buryat State University
Russian Federation
Russian Federation
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Review
For citations:
Gulyayev S.M., Arkhipova E.V., Lemza S.V., Khamayeva N.A., Nikolayev S.M. Influence of thyrotropic herbal remedy on vascular endothelium and thyroid gland structure in experimental hypothyroidism. Acta Biomedica Scientifica. 2014;(3):97-100. (In Russ.)
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