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THE RESULTS OF THE STUDY OF TOPOGRAPHIC ANATOMY OF THYROID AND PARATHYROID GLANDS OF RAT

Abstract

In this study we investigated the anatomy of thyroid and parathyroid glands of female Wistar rats line. Thyroid gland consists of two lateral lobes, the right and left, and the isthmus. Each lobe has cranial and caudal poles. Cranial poles of the lateral lobes of thyroid gland reach the height of the cricoid cartilage or the caudal edge of thyroid cartilage plates. Caudal poles of the lateral lobes of the thyroid gland come down below the isthmus and reach the level of 4-5th tracheal rings. The isthmus joins both thyroid lobes and is in front of the trachea (on the level from the 1st to the 3rd or from the 2nd to the 4th tracheal cartilages). Parathyroid glands are pair rounded organs, up to 1-1,2 mm in diameter, yellow-cream and are placed in the upper third of both lobes of the thyroid gland on laterocranial surfaces. The blood supply comes from the cranial thyroid artery and at the localization in the middle third of thyroid gland lobes - partially from caudal thyroid artery. Venous drainage is carried out in the veins corresponding to the arteries. The correlation between the age of the animal with the anatomical structure of the parathyroid glands was revealed: with increasing age of the animal connective tissue capsule becomes severe, the parathyroid gland is differentiated from the tissues of the thyroid gland and rises above its surface. From the point of view of experimental modeling of abnormalities of the thyroid and parathyroid glands it is necessary to take into account the identified feature and to use the animals of least 10 months to study the pathogenic mechanisms of organ failure formation and to search new methods of correction.

About the Authors

A. V. Ayusheeva
Scientific Center of Reconstructive and Restorative Surgery SB RAMS
Russian Federation


O. A. Goldberg
Irkutsk State Medical University
Russian Federation


E. A. Iljicheva
Scientific Center of Reconstructive and Restorative Surgery SB RAMS
Russian Federation


S. A. Lepekhova
Irkutsk State Medical University; Irkutsk Scientific Center SB RAS
Russian Federation


I. S. Kurganskiy
Irkutsk State Medical University
Russian Federation


A. E. Akhmedov
Scientific Center of Reconstructive and Restorative Surgery SB RAMS
Russian Federation


References

1. Ильичева Е.А., Махутов В.Н., Рой Т.М. Анализ 32 случаев хирургического лечения рецидивного диффузного токсического и многоузлового зоба: еще один аргумент в пользу первичной тиреоидэктомии // Бюл. ВСНЦ СО РАМН. - 2011. - № 4 (80), Ч. 2. - С. 74-79.

2. Лепехова С.А. Программа стандартных операционных процедур: лабораторные животные (прием, содержание, уход и контроль здоровья животных в вивариях медицинского учреждения): учеб. пособие. - Иркутск: НЦРВХ СО РАМН; ИГМУ, 2012. - 96 с.

3. Ноздрачев А.Д., Поляков Е.Л. Анатомия крысы (лабораторные животные) / Под ред. академика А.Д. Ноздрачева. - СПб.: Издательство «Лань», 2001. -464 с.

4. Сашков В.А., Джандарова Т.И., Сельверова Н.Б. Взаимосвязь уровня общего кальция в крови и катехоламинов в мозге в процессе формирования и закрепления памятного следа при гипопаратиреозе // Ж. высшей нервной деятельности им. И.П. Павлова. - 2006. - № 4. - С. 529-536.

5. Halloran B., Udén P., Duh Q.Y., Kikuchi S. et al. Parathyroid gland volume increases with postmaturational aging in the rat // Am. J. Physiol. Endocrinol. Metab. -2002. - Vol. 282 (з). - P. E557-E563.

6. Iwasaki Y., Kazama J.J., Yamato H., Shimoda H. et al. Accumulated uremic toxins attenuate bone mechanical properties in rats with chronic kidney disease // Bone. - 2013. - Aug 3. - doi: pii: S8756-3282(13)002998. 10.1016/j.bone.2013.07.037.

7. Lee K.E., Kim E., Koo do H., Choi J.Y. et al. Robotic thyroidectomy by bilateral axillo-breast approach: review of 1,026 cases and surgical completeness // Surg. Endosc. - 2013. - N 27 (8). - P. 2955-2962.

8. Maschuw K., Schlosser K., Lubbe D., Nies C. et al. Total versus near-total thyroidectomy in Graves’ disease and their outcome on postoperative transient hypoparathyroidism: study protocol for a randomized controlled trial? // Trials. - 2012. - Dec 6, Vol. 13. - P. 234.

9. Russell P.S., Gittes R.F. Parathyroid transplants in rats a comparison of their survival time with that of skin grafts // J. Exp. Med. - 1959. - June 1, Vol. 109 (6). -P. 571-588.

10. Sousa Ade A., Salles J.M., Soares J.M., Moraes G.M. et al. Predictors factors for post-thyroidectomy hypocalcaemia // Rev. Col. Bras. Cir. - 2012. - Dec, Vol. 39 (6). -P. 476-482.


Review

For citations:


Ayusheeva A.V., Goldberg O.A., Iljicheva E.A., Lepekhova S.A., Kurganskiy I.S., Akhmedov A.E. THE RESULTS OF THE STUDY OF TOPOGRAPHIC ANATOMY OF THYROID AND PARATHYROID GLANDS OF RAT. Acta Biomedica Scientifica. 2014;(1):64-70. (In Russ.)

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ISSN 2541-9420 (Print)
ISSN 2587-9596 (Online)