Preview

Acta Biomedica Scientifica

Advanced search

Changes in the system of physiological anticoagulants at arterial hypertension in children

Abstract

At labile and stable hypertension (AH) practically we revealed equal number of patients with decreased activity of protein C system (PS), antithrombin-IH (AT-ПІ), protein C (PS), Leiden anomaly. With stable hypertension decreased activity of PS was more pronounced. Reduced activity of PS was found only in children with stable hypertension. Significantly greater number of patients with decreased activity PS were revealed at stable hypertension. Comprehensive study of hemostasis is advisable in children with AH.

About the Authors

V. V. Dolgikh
Scientific Centre of Family Health and Human Reproduction Problems SB RAMS
Russian Federation


M. V. Gomellya
Scientific Centre of Family Health and Human Reproduction Problems SB RAMS; Irkutsk State Medical University
Russian Federation


E. S. Filippov
Irkutsk State Medical University
Russian Federation


L. V. Rychkova
Scientific Centre of Family Health and Human Reproduction Problems SB RAMS
Russian Federation


References

1. Бугун О.В., Рычкова Л.В., Долгих В.В. Двадцатичетырехчасовое мониторирование артериального давления в диагностике эссенциальной артериальной гипертензии // Бюл. СО РАМН. - 2003. - № 2. - С. 49-53.

2. Погодина А.В., Долгих В.В., Рычкова Л.В. Эпидемиологические аспекты артериальной гипертензии у детей и подростков // Кардиология - 2006: материалы VIII Всерос. науч.-образоват. форума. - 2006. -С. 111-112.

3. Нефедова Ж.В. Метаболические и нейрофизиологические аспекты артериальной гипертензии у детей и подростков: автореф. дис.. д-ра мед. наук. -Новосибирск, 2007. - 43 с.

4. Подчерняева Н. Тромбоз в педиатрической практике // Врач. - 2006. - № 9. - С. 20-23.

5. Чупрова А.В., Хозяинова Ж.В., Соловьев О.Н., Яхонтов Д.А. Состояние системы свертывания крови при артериальной гипертензии у детей // Педиатрия. - 1998. - № 6. - С. 48-52.

6. Biller J. Strokt in the young // Cerebrovascular disorders. - Philadelphia, PA, 1999. - P. 283-316.

7. Salomaa V., Rasi V., Kulantinal S. et al. Haemostatic factors a predictors of coronary events and total mortality // Arteriosclerosis, Thrombosis and Vascular Bioligy. - 2002. - Vol. 22, N 2. - P. 353-358.

8. Woodward M., Lowe G.D., Rumley A. et al. Epidemiology of coagulation factors, inhibitors and activation markers: The Third Glasgow Monica Survey II. Relationships to cardiovascular risk factors and prevalent cardiovascular disease // Br. J. Haematol. - 1997. - Vol. 97. -P. 785-797.

9. Ridker P.M., Gaboury C.L., Conlin P.R. et al. Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function // Circulation. - 1993. - Vol. 87. -P. 1969-1973


Review

For citations:


Dolgikh V.V., Gomellya M.V., Filippov E.S., Rychkova L.V. Changes in the system of physiological anticoagulants at arterial hypertension in children. Acta Biomedica Scientifica. 2013;(6):29-32. (In Russ.)

Views: 437


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2541-9420 (Print)
ISSN 2587-9596 (Online)