CLINICAL AND ANAMNESTICAL FEATURES OF JUVENILE CHRONIC ARTHRITIS IN THE REPUBLIC OF BURYATIA

Abstract

Article is devoted to the study of the epidemiology of juvenile arthritis in children in the Republic of Buryatia. All-Russian register of juvenile arthritis (JA) by the Republic of Buryatia (RB) is 48 patients aged 10,2 ± 5,1 years, with a mean disease duration of 3,4 ± 3,2 years, including 26 boys and 22 girls. There is a high incidence of JA in the Republic of Buryatia, which is 21,2 to 100,000 child population. Age of onset of the disease falls on school years and is 7,1 ± 4,5 years. Marked the beginning of the peak age 2 JA: 1-3 years 31,2 %, and 8-12 years 39,5 %. In 66,6 % of cases occur oligoarticular form JA. More than half of patients have extra-articular manifestations of JA, the majority of which occur in the reaction of lymphoproliferative (lymphadenopathy, hepatosplenomegaly). 56,2 % of patients with JA have a disability, 70 % of it is set in the first year of the disease. 90 % of patients with JA being treated with methotrexate, of whom 69 % are on conjoint immunosuppressive therapy, including 13 % genetically engineered biological agents.