SOME FUNCTIONAL FEATURES OF COURSE OF BRONCHIAL ASTHMA COMBINED WITH ESSENTIAL HYPERTENSION
Abstract
One of the frequent conditions which accompany bronchial asthma is essential hypertension. The authors compared the functional characteristics of patients with isolated asthma and bronchial asthma combined with essential hypertension. As a result the parameters of spirometry in group ofcomorbid disorders are significantly more decreased than in the group of isolated bronchial asthma: FEV1 [% predicted) before the testwith bronchodilator84,3 ± 1,28 and 85,7 ±2,63 (p < 0,05); the percent of increase in FEV1 after bronchodilator testis 6,5 ± 0,8 and 7,45 ± 0,3 (p < 0,05); fraction of exhaled nitric oxide (ppb) is 24,6 ± 1,15 and 27,6 ± 1,8. Exhaled NO level is higher in patients with bronchial asthma and arterial hypertension and in patients with atopy.
About the Authors
O. M. Uryasev
Ryazan State Medical University
Russian Federation
Russian Federation
A. I. Rogachikov
Ryazan State Medical University
Russian Federation
Russian Federation
References
1. Зарипова Т.Н., Антипова И.И., Смирнова И.Н., Ляпунова И.Ю. Клинико-функциональные особенности течения бронхиальной астмы в сочетании с гипертонической болезнью //Бюллетень сибирской медицины. - 2009. - № 4. - С. 33-37.
2. Урясьев O.M. Бронхиальная астма и коморбид- ная кардиальная патология: частота и клинико-функциональные особенности // Земский врач. - 2013. - № 3 (20]. - С. 22-27.
3. Чучалин А.Г., Айсанов 3.P., Чикина С.Ю., Черняк A.B., Калманова Е.Н. Федеральные клинические рекомендации по использованию метода спирометрии // Пульмонология. - 2014. - № 6. - С. 11-23.
4. Шустов С.Б., Барсуков A.B. Артериальная гипертензия в таблицах и схемах. Диагностика и лечение; изд. 2-е, перераб. и доп. - СПб.: ЭЛБИ-СПб, 2004. -126 с.
5. American Thoracic Society (2005]. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide. Am.]. Respir. Crit Care Med., 171,912-930.
6. Kojda G, Harrison D (1999]. Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure. Cardiovasc. Res., 43 (3], 562-571.
7. Quark NObreath [Digital Source]. - http://www. cosmed.com/en/products/pulmonaiy-function/quark-no- breath-nitric-oxide-monitor (access date 18.07.2015].
8. Smith CJ et al. (2011]. Upregulation of inducible nitric oxide synthase contributes to attenuated cutaneous vasodilation in essential hypertensive humans. Hypertension, 58 (5], 935-942.
9. Stewart L, Katial RK (2012]. Exhaled nitric oxide. Immunol. Allergy Clin. North Am., 32 (3], 347-362.
Review
For citations:
Uryasev O.M., Rogachikov A.I. SOME FUNCTIONAL FEATURES OF COURSE OF BRONCHIAL ASTHMA COMBINED WITH ESSENTIAL HYPERTENSION. Acta Biomedica Scientifica. 2015;(5):44-46. (In Russ.)
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