Preview

Acta Biomedica Scientifica

Advanced search

STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF CHANGES IN PANCREAS IN CONDITIONS OF EXPERIMENTAL ACUTE PANCREATITIS IN GUINEA-PIGS

Abstract

The article determined that experimental acute pancreatitis in guinea-pigs was initially characterized by microcirculation disorders with further damage of parenchyma and stroma of the organ. Obtained, results confirm. primary vascular lesions with development ischemic symptom complex at the acute pancreatitis, that testifies to the necessity of further studies on the effectiveness of use of antioxidants at this pathology.

About the Authors

A. A. Chegodaeva
Orenburg State Medical Academy
Russian Federation


M. S. Funygin
Orenburg State Medical Academy
Russian Federation


References

1. Автандилов Г.Г. Медицинская морфометрия. - М.: Медицина. - 1990. - 260 с.

2. Кубышкин В.А. Лечебная тактика при панкреонекрозе // Анналы хирургической гепатологии. - 1996. - № 1. - С. 148.

3. Пирс Э. Гистохимия теоретическая и прикладная. - М.: ИЛ, 1962. - 610 с.

4. Руднов В.А., Зубарев А.С. Интенсивная терапия некротизирующего панкреатита: анализ современного состояния // Русский медицинский журнал. - 2005. - Т. 13, № 26. - С. 1774-1778.

5. Савельев В.С., Филимонов М.И., Гельфанд Б.Р., Бурневич С.З. Деструктивный панкреатит: алгоритм диагностики и лечения (проект) // Consilium Medicum. - 2001. - Т. 3, № 6. -С. 273 - 279.

6. Смирнов Д.А., Ходосевич Л.С., Плащевский А.Т. Диагностика мембранных нарушений при остром панкреатите // Хирургия. - 1990. -№ 1. - С. 49 - 52.

7. Bonner-Weiz S. Pancreatic stem cells // J. Pathol. - 2002. - Vol. 197, N 3. - P. 519 - 526.

8. Kim So-Yoon, Lee S.H., Bendayan M.H. Activation of nestin-positive duct stem cells in pancreas // Dev. Dynamics. - 2004. - Vol. 230, N 1. -P. 1-11.

9. Nonaka A., Mahabe T., Kyogoku T. et al. The role of free radical in the development of acute mild and severe pancreatitis in mice // Nippon Shokakibyo Gakkai Zasshi. - 1990. - Vol. 87. - P. 1212-1216.

10. Reynolds E.S. The use of lead citrate at high pH as an electronopaque stain in electron microscopy // J. Cell. Biol. - 1963. - Vol. 17. - P. 203 - 213.

11. Sunamura M., Yamauchi J., Shibuya K., Chen H.M. et al. Pancreatic microcirculation in acute pancreatitis // J. Hepatobiliary Pancreat. Surg. -1998. - Vol. 5 (1). - P. 62 - 68.


Review

For citations:


Chegodaeva A.A., Funygin M.S. STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF CHANGES IN PANCREAS IN CONDITIONS OF EXPERIMENTAL ACUTE PANCREATITIS IN GUINEA-PIGS. Acta Biomedica Scientifica. 2012;(4(2)):210-212. (In Russ.)

Views: 469


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2541-9420 (Print)
ISSN 2587-9596 (Online)