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INCOMPLETE CORONARY REVASCULARIZATION AS AN INDEPENDENT RISK FACTOR OF OFF-PUMP CORONARY ARTERY BYPASS GRAFTING PROGNOSIS IN PATIENTS WITH ISCHEMIC HEART DISEASE

https://doi.org/10.12737/article_59a614f8afcde0.78457348

Abstract

Currently, most researchers define the term complete coronary revascularization (CCR) as coronary arterial bypass graft (CABG) of at least one branch of each of the three affected coronary basins: left anterior descending artery (LAD) left circumflex artery (LCA) and right coronary artery RCA. The rejection of bypass of one or more diseased coronary basin is estimated as an incomplete coronary revascularization (ICR). Material and methods. This retrospective study included patients, underwent isolated coronary bypass operations from 2001 to 2014 in the Irkutsk Regional Hospital. 1418 patients underwent isolated off-pump bypass operations. ICR occurred in 469 patients, the CCR - in 949. All patients were divided into 2 groups: ICR group and CCR group. These groups were compared by the late survival and by the frequency of the major cardiac events (MACE). The results of study were assessed after 1, 5 and 10 years from the date of CABG. Results. Survival of patients of ICR group after 1,5,10 years after surgery was 98.5 %, 75.4 % and 75.4 % respectively, of CCR group of patients - 98.7 %, 88.7 % and 81.3 % (p = 0.006). In ICR group "free" from MACE after 1, 5 and 10 years after surgery were respectively 98.2 %, 70.8 % and 61.0 % of patients, while in CCR group those made 98.3 %, 84.6 % and 72,6 % (p = 0,007). We can conclude that incomplete revascularization can be defined as a prediction factor of worst long-term outcome results of CABG.

About the Authors

V. A. Podkamenniy
Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Russian Medical Academy of Continuing Professional Education; Irkutsk Regional Clinical Hospital
Russian Federation


D. I. Likhandi
Irkutsk Regional Clinical Hospital
Russian Federation


Y. V. Zheltovsky
Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Russian Medical Academy of Continuing Professional Education; Irkutsk State Medical University; Irkutsk Regional Clinical Hospital
Russian Federation


A. A. Sharavin
Irkutsk Regional Clinical Hospital
Russian Federation


A. V. Vyrupaev
Irkutsk Regional Clinical Hospital
Russian Federation


References

1. Bell M.R., Gersh B.J., Shaff H.V., Holmes D.R., Fisher L.D., Alderman E.L., Myers W.O., Parsons L.S., Reeder G.S. (1992). Effect of completeness of revascularization on long-term outcome of patients with three-vessel disease undergoing coronary artery bypass grafting: A report from CASS registry. Circulation, 86, 446-457.

2. Girerd N., Magne J., Rabilloud M., Charbonneau E., Mohamadi S., Pibarot P., Voisine P., Baillot R., Doyle D., Dumont E., Dagenais F., Mathieu P. (2012). The impact of complete revascularization on long-term survival is strongly dependent on age. Ann. Thorac. Surg., 94, 11661172.

3. Head S.J., Mack M.J., Holmes D.R. Jr., Piroze M.D., Serruys P.W., Redwood S.R., Colombo A., Morice M., Feldman T.E., Stähle E., Underwood P., Dawkins K.D., Kappetein A.P., Mohr F.W. (2012). Incidence, predictors and outcomes of incomplete revascularization after percutaneous coronary intervention and coronary artery bypass grafting: a subgroup analysis of 3-year SYNTAX data. Eur. J. Cardiothorac. Surg., 41, 535-541.

4. Kozower B.D., Moon M.R., Barner H.B., Moazami N., Lawton J.S., Pasque M.K., Damiano R.J. Jr. (2005). Impact of complete revascularization on long-term survival after coronary artery bypass grafting in octogenarians. Ann. Thorac. Surg., 80, 112-117.

5. Mocanu V., Buth K.J., Kelly R., Légaré J.F. (2014). Incomplete revascularization after coronary artery bypass graft operations is independently associated with worse long-term survival. Ann Thorac. Surg., 92, 549-555.

6. Osswald B.R., Blackstone E.H., Tochtermann U., Schweiger P., Thomas G. (2001). Does the completeness of revascularization affect early survival after coronary artery bypass grafting in elderly patients? Eur. J. Cardiothorac. Surg., 20, 120-126.

7. Rastan A.J., Walther T., Falk V., Kempfert J., Merk D., Lehmann S., Holzhey D., Mohr F.W. (2009). Does reasonable incomplete surgical revascularization affect early or long term survival in patients with multivessel coronary artery disease receiving left internal mammary artery bypass to left anterior descending artery? Circulation, 120, 70-77.

8. Scott R., Blackstone E.H., McCarthy P.M., Lytle B.W., Loop F.D., White J.A., Cosgrove D.M. (2000). Isolated bypass grafting of the left internal thoracic artery to the left anterior descending coronary artery: Late consequences of incomplete revascularization. J. Thorac. Cardiovasc. Surg., 120, 173-184.

9. Sergeant P., Blackstone E.H., Meyns B. (1997). Validation and interdependence with patientvariables of the influence of procedural variables on early and late phase after CAGB. Eur. J. Cardiothorac. Surg., 12, 1-9.

10. Synnergren M.J., Ekroth R., Odén A., Rexius H., Wiklund L. (2008). Incomplete revascularization reduces survival benefit of coronary artery bypass grafting: Role of off-pump surgery. J. Thorac. Cardiovasc. Surg., 136, 29-36.


Review

For citations:


Podkamenniy V.A., Likhandi D.I., Zheltovsky Y.V., Sharavin A.A., Vyrupaev A.V. INCOMPLETE CORONARY REVASCULARIZATION AS AN INDEPENDENT RISK FACTOR OF OFF-PUMP CORONARY ARTERY BYPASS GRAFTING PROGNOSIS IN PATIENTS WITH ISCHEMIC HEART DISEASE. Acta Biomedica Scientifica. 2017;2(2):40-44. (In Russ.) https://doi.org/10.12737/article_59a614f8afcde0.78457348

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ISSN 2541-9420 (Print)
ISSN 2587-9596 (Online)