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Structure and analysis of complications of surgical treatment of non-organ-confined retroperitoneal tumors

https://doi.org/10.29413/ABS.2018-3.2.8

Abstract

The article presents retrospective analysis of complications of surgeries for non-organ-confined retroperitoneal tumors. The study includes information about 236 patients operated between 1996 and 2016 in Irkutsk Regional Cancer Center. All patients were divided into two groups: main group (n = 102] with resection of non-organ-confined retroperitoneal tumors in extended and combined version, and control group (n = 134] with isolated removal of tumor. The patients, who received combined version of operations, are presented in two groups (mono-organ resection group (n = 50] and multi-organ resection group (n = 52]]. Postoperative deaths and complications in these groups were analyzed. Clavien - Dindo classification was used in examining the structure of postoperative complications. 1t was established, that postoperative complications occurred in 44 (19 %] cases. The most frequent ones were intra-abdominal bleeding (3.8 %], wound infection (3 %], femoral nerve neuropathy (2.1 %] and abscess of abdominal cavity or small pelvis (2.1 %]. Among patients with isolated removal of non-organ-confined retroperitoneal tumors, post-operative complications made 14 % (16 cases]. Post-operative complications in the group with extended and combined resection of non-organ-confined retroperitoneal tumors reached 23 % (28 cases]. Accordingly, it was established that enhancing volume of surgery substantially increases frequency of post-operative complications (p = 0.02]. Surgical treatment of non-organ-confined retroperitoneal tumors involve developing post-operative complications of third degree, according to Clavien - Dindo classification. The complications demand invasive manipulation for their management. While examining the structure of extended and combined operations, in comparison with mono-organ resections, multi-visceral resections do not substantially increase the number of post-operative complications (p = 0.903). Most of complications were controlled and their timely management led to full recovery of patients.

About the Authors

R. I. Rasulov
Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Russian Medical Academy of Continuing Professional Education; Irkutsk Regional Cancer Center
Russian Federation


A. A. Muratov
Irkutsk State Medical Academy of Postgraduate Education -Branch Campus of the Russian Medical Academy of Continuing Professional Education; Irkutsk Regional Cancer Center
Russian Federation


V. V. Dvornichenko
Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Russian Medical Academy of Continuing Professional Education; Irkutsk State Medical University; Irkutsk Regional Cancer Center
Russian Federation


References

1. Давыдов М.М., Мачаладзе З.О. Саркомы торако -абдоминальной локализации (современная стратегия хирургического лечения) // Вестник РОНЦ им. Н.Н. Блохина. - 2015. - № 1. - С. 3-14

2. Поляков В.Г., Рябов А.Б., Ким Э.Ф., Лебедев В.И., Казанцев А.П., Керимов П.А., Рубанский М.А., Нечушкина И.В., Капкова О.А., Рубанская М.А., Рыбакова Д.В. Хирургический метод при опухолях торакоабдоминальной локализации у детей: современное состояние проблемы и опыт клиники // Онкопедиатрия. 2014. - № 1. - С. 13-19

3. Стилиди И.С., Губина Г.И., Неред С.Н., Клименков А.А., Сельчук В.Ю., Тюрин И.Е., Назлиев П.Б. Непосредственные результаты хирургического лечения неорганных забрюшинных опухолей // Российский онкологический журнал. - 2007. - № 1. - С. 25-28

4. Bonvalot S, Rivoire M, Castaing M, Stoeckle E, Le Cesne A, Blay JY, Laplanche A. (2009). Primary retroperitoneal sarcomas: a multivariate analysis of surgical factors associated with local control. J Clin Oncol, 27 (1), 31-37. doi: 10.1200/JCO.2008.18.0802

5. Clavien PA, Sanabria JR, Strasberg SM. (1992). Proposed classification of complications of surgery with examples of utility in cholecystectomy. Surgery, 111 (5), 518-526.

6. Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, de Santibanes E, Pekolj J, Slankamenac K, Bassi C, Graf R, Vonlanthen R, Padbury R, Cameron JL, Makuuchi M. (2009). The Clavien - Dindo classification of surgical complications: five-year experience. Ann Surg, 250 (2), 187-196. doi: 10.1097/SLA.0b013e3181b13ca2

7. Dindo D, Demartines N, Clavien PA. (2004). Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg, 240 (2), 205-213

8. Gronchi A, Bonvalot S, Le Cesne A, Casali PG. (2009). Resection of uninvolved adjacent organs can be part of surgery for retroperitoneal soft tissue sarcoma. J Clin Oncol, 27 (12), 2106-2107

9. Gronchi A, Lo Vullo S, Fiore M, Mussi C, Stacchiotti S, Collini P, Lozza L, Pennacchioli E, Mariani L, Casali PG. (2009). Aggressive surgical policies in a retrospectively reviewed single-institution case series of retroperitoneal soft tissue sarcoma patients. J Clin Oncol, 27 (1), 24-30. doi: 10.1200/JCO.2008.17.8871

10. Lewis JJ, Benedetti F. (1997). Adjuvant therapy for soft tissue sarcomas. Surg Oncol Clin N Am, 6 (4), 847-862.

11. Pisters PW. (2009). Resection of some - but not all - clinically uninvolved adjacent viscera as part of surgery for retroperitoneal soft tissue sarcomas. J Clin Oncol, 27 (1), 6-8. doi: 10.1200/JC0.2008.18.7138


Review

For citations:


Rasulov R.I., Muratov A.A., Dvornichenko V.V. Structure and analysis of complications of surgical treatment of non-organ-confined retroperitoneal tumors. Acta Biomedica Scientifica. 2018;3(2):44-49. (In Russ.) https://doi.org/10.29413/ABS.2018-3.2.8

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