Experimental confirmation of the bactericidal action of the domestic antiseptic “Anolit” in surgical practice
S. N. Styazhkina,
D. N. Kuklin,
V. V. Tikhonova,
S. G. Gushchin,
Y. S. Bazhina,
I. I. Gaynetdinova,
S. B. Tulynin https://doi.org/10.29413/ABS.2024-9.5.14
Abstract
Background. Antimicrobial resistance is one of the most serious threats to modern clinical medicine. Despite the significant successes of modern pharmacology, the search for effective antiseptics that can influence wound processes continues. In our study, an experimental study of the effect of Anolit solution on pathogenic microorganisms Pseudomonas aeruginosa and Proteus mirabilis was conducted.
The aim. To evaluate the antimicrobial activity of the domestic antiseptic “Anolit” against gram-negative pathogens of nosocomial infections using the example of P. aeruginosa and P. mirabilis.
Methods. To assess the quality of the effect of “Anolit” on the studied colonies of microorganisms, experimental studies were performed in vitro. The bacteriological study was carried out in three stages using the Koch method.
Results. “Anolit” is a modern antiseptic agent with a pronounced antimicrobial effect based on the electrolysis of aqueous solutions. Its ability to lyse pathogenic microorganisms (P. aeruginosa and P. mirabilis) has been confirmed by experimental research.
Conclusion. The bactericidal effect of “Anolit” on the growth of gram-negative bacteria is shown, proving its high antimicrobial efficacy.
About the Authors
S. N. Styazhkina
Izhevsk State Medical Academy
Russian Federation
Russian Federation
Svetlana N. Styazhkina – Dr. Sc. (Med.), Professor of the Department of Faculty Surgery
Kommunarov str., 281, Izhevsk 426056
D. N. Kuklin
First Republican Clinical Hospital of the Ministry of Health of the Udmurt Republic
Russian Federation
Russian Federation
Dmitry N. Kuklin – Urologist
Votkinskoe Highway, 57, Izhevsk 426039
V. V. Tikhonova
Izhevsk State Medical Academy
Russian Federation
Russian Federation
Valentina V. Tikhonova – Cand. Sc. (Biol.), Associate Professor at the Department of Microbiology and Virology
Kommunarov str., 281, Izhevsk 426056
S. G. Gushchin
Izhevsk State Medical Academy
Russian Federation
Russian Federation
Sergey G. Gushchin – Postgraduate at the Department of Faculty Surgery
Kommunarov str., 281, Izhevsk 426056
Y. S. Bazhina
Izhevsk State Medical Academy
Russian Federation
Russian Federation
Yulia S. Bazhina – Student of the Faculty of Medicine
Kommunarov str., 281, Izhevsk 426056
I. I. Gaynetdinova
Izhevsk State Medical Academy
Russian Federation
Russian Federation
Inna I. Gaynetdinova – Student of the Faculty of Medicine
Kommunarov str., 281, Izhevsk 426056
S. B. Tulynin
Izhevsk State Medical Academy
Russian Federation
Russian Federation
Stepan B. Tulynin – Student of the Faculty of Medicine
Kommunarov str., 281, Izhevsk 426056
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Review
For citations:
Styazhkina S.N., Kuklin D.N., Tikhonova V.V., Gushchin S.G., Bazhina Y.S., Gaynetdinova I.I., Tulynin S.B. Experimental confirmation of the bactericidal action of the domestic antiseptic “Anolit” in surgical practice. Acta Biomedica Scientifica. 2024;9(5):135-141. (In Russ.) https://doi.org/10.29413/ABS.2024-9.5.14
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