Unstable Hemostasis and Specific Postoperative Complications (Literature Review)
https://doi.org/10.29413/ABS.2020-5.4.14
Abstract
Perioperative bleeding occupies a leading place among all surgical complications and, despite the rapid development of surgery, remains relevant to this day. In addition to an increase in mortality, bleeding can cause the development of other postoperative complications, which lead to disability of patients and to a decrease in the quality of life in all age groups. Most perioperative bleeding are caused by technical errors. This article reviews the problem of perioperative bleeding from the point of view of impaired coagulation capabilities of the body. The main etiopathogenetic features of hemostasis during the development of this complication are considered. The analysis of postoperative complications, which were directly or indirectly caused by bleeding during or after surgery, is presented. The prevalence of these complications in various areas of surgery has been demonstrated. More detailed study of the hemostasis system and the identification of predictors of hemostasis difficulties before the surgery may cause an improvement in the results of surgical treatment and reduce the number of postoperative complications and the duration of hospital stay. Accordingly, this will lead to a decrease in the cost of treatment and an increase in patient satisfaction with the medical care. In connection with the above, there is a great interest among surgeons and anesthesiologists in preventing the development of perioperative bleeding.
About the Authors
D. V. LebedevaRussian Federation
Darya V. Lebedeva – Postgraduate at the Department of Advanced Level Surgery
Krasnogo Vosstaniya str. 1, Irkutsk 664003
E. A. Ilyicheva
Russian Federation
Elena A. Ilyicheva – Dr. Sc. (Med.), Professor, Head of the Scientific Department of Clinical Surgery; Surgeon at the Thoracic Surgery Unit
Bortsov Revolyutsii str. 1, Irkutsk 664003
Yubileyniy 100, Irkutsk 664049
References
1. Marietta M, Facchini L, Pedrazzi P, Busani S, Torelli G. Pathophysiology of bleeding in surgery. Transplant Proc. 2006; 38(3): 812-814. doi: 10.1016/j.transproceed.2006.01.047
2. Freundlich RE, Maile MD, Sferra JJ, Jewell ES, Kheterpal S, Engoren M. Complications associated with mortality in the National Surgical Quality Improvement Program Database. Anesth Analg. 2018; 127(1): 55-62. doi: 10.1213/ANE.0000000000002799
3. Agadzhanyan VV, Kravtsov SA, Shatalin AV, Levchenko TV. Hospital mortality in polytrauma and the main directions of its reduction. Polytrauma. 2015; 1: 6-15. (In Russ.)
4. Marietta M, Pedrazzi P, Girardis M, Luppi M. Massive bleeding: Are we doing our best? Transfus Apher Sci. 2011; 45(3): 287-290. doi: 10.1016/j.transci.2011.10.010
5. Seidlová D, Buliková A. Hemoragický šok a léčba masivního krvácení [Hemorrhagic shock and treatment of severe bleeding]. Vnitr Lek. 2019; 65(3): 211-218.
6. Güllüoglu BM, Manukyan MN, Cingi A, Yegen C, Yalin R, Aktan AO. Early prediction of normocalcemia after thyroid surgery. World J Surg. 2005; 29(10): 1288-1293.
7. Sniecinski RM, Chandler WL. Activation of the hemostatic system during cardiopulmonary bypass. Anesth Analg. 2011; 113: 1319-1333.
8. Achneck HE, Sileshi B, Jamiolkowski RM, Albala DM, Shapiro ML, Lawson JH. A comprehensive review of topical hemostatic agents: efficacy and recommendations for use. Ann Surg. 2010; 251: 217-228.
9. Russian clinical guidelines for the diagnosis, treatment and prevention of venous thromboembolic complications. Flebologiya. 2015; 4(9): 1-52. (In Russ.)
10. Dutkevich IG. Algorithm for emergency diagnosis of acute bleeding caused by hemostasis disorders in surgical practice. Grekov’s Bulletin of Surgery. 2012; 171(6): 89-93. (In Russ.)
11. Ghadimi K, Levy JH, Welsby IJ. Perioperative management of the bleeding patient. Br J Anaesth. 2016; 117(Suppl 3): iii18-iii30. doi: 10.1093/bja/aew358
12. Zemlyanoy AB. Local hemostasis agent – fluid active hemostatic matrix. Pirogov Russian Journal of Surgery. 2019; (5): 104-115. doi: 10.17116/hirurgia2019051104. (In Russ.)
13. Stokes ME, Ye X, Shah M, Mercaldi K, Reynolds MW, Rupnow MFT, et al. Impact of bleeding-related complications and/or blood product transfusions on hospital costs in inpatient surgical patients. BMC Health Serv Res. 2011; 11: 135(2011). doi: 10.1186/1472-6963-11-135
14. Jarnagin WR, Gonen M, Fong Y, DeMatteo RP, Ben-Porat L, Little S, et al. Improvement in perioperative outcome after hepatic resection: analysis of 1,803 consecutive cases over the past decade. Ann Surg. 2002; 236(4): 397-407. doi: 10.1097/01.SLA.0000029003.66466.B3
15. Kurbonov KM, Makhmadov FI, Rasulov NA, Nazirboev KR, Mansurov UU. Causes and tactics of treatment of recent injuries of the bile ducts. Novosti khirurgii. 2016; 24(2): 120-124. doi: 10.18484/2305-0047.2016.2.120. (In Russ.)
16. Krasilnikov DM, Mirgasimova DM, Abdulyanov AV, Shigabutdinov RR, Zakharova AV. Complications of laparoscopic cholecystectomy. Prakticheskaya meditsina. 2016; 4-1(96): 110- 113. (In Russ.)
17. Pevzner P.N. The main provisions of the prevention of bleeding, obstructive and inflammatory complications of transvesical prostate adenomectomy. Clinical Medicine. 1999; 4: 374-381. (In Russ.)
18. Ogiwara H, Dubner S, Shafizadeh S, Raizer J, Chandler JP. Spindle cell oncocytoma of the pituitary and pituicytoma: two tumors mimicking pituitary adenoma. Surg Neurol Int. 2011; 2: 116. doi: 10.4103/2152-7806.83932
19. Kalinin PL, Kadashev BA, Fomichev DV, Kutin MA, Astafieva LI, Sharipov OI, et al. Surgical treatment of pituitary adenomas. Burdenko’s Journal of Neurosurgery. 2017; 81(1): 95-107. doi: 10.17116/neiro201780795-107. (In Russ.)
20. Azizyan VN, Grigoriev AYu, Ivashchenko OV, Molitvoslovova NN. Intraoperative hemorrhage in the pituitary adenoma as a cause of remission of acromegaly. Endokrinnaya khirurgiya. 2011; 5(1): 39-44. (In Russ.)
21. Kalinin PL, Fomichev DV, Chernov IV, Kutin MA, Shkarubo AN, Ismailov DB, et al. Endoscopic endonasal removal by pituicitis and oncocytoma. The Russian Journal of Neurosurgery. 2018; 20(1): 21-32. doi: 10.17650/1683-3295-2018-20-1-21-32. (In Russ.)
22. Krylov VV, Grin AA, Gushcha AO, Rozental D, Evzikov GYu, Timerbaev VKh, et al. Video endoscopy and video endoscopic assistance in spinal injuries and diseases. Moscow: Print-Studio; 2017. (In Russ.)
23. Khadra H, Bakeer M, Hauch A, Hu T, Kandil E. Hemostatic agent use in thyroid surgery: a meta-analysis. Gland Surg. 2018; 7(Suppl 1): S34-S41.
24. Shulutko AM, Semikov VI, Gryaznov SE, Gorbacheva AV, Patalova AR, Mansurova GT, et al. Risk of hypocalcemia after surgery on the thyroid gland. Pirogov Russian Journal of Surgery. 2015; 11: 35-40. doi: 10.17116/hirurgia20151135-40. (In Russ.)
25. Edafe O, Antakia R, Laskar N, Uttley L, Balasubramanian SP. Systematic review and metaanalysis of predictors of postthyroidectomy hypocalcaemia. Br J Surg. 2014; 101(4): 307-320. doi: 10.1002/bjs.9384
26. Kakava K, Tournis S, Papadakis G, Karelas I, Stampouloglou P, Kassi E, et al. Postsurgical hypoparathyroidism: a systematic review. In Vivo. 2016; 30(3): 171-179.
27. Sakorafas GH, Stafyla V, Bramis C, Kotsifopoulos N, Kolettis T, Kassaras G. Incidental parathyroidectomy during thyroid surgery: an underappreciated complication of thyroidectomy. World J Surg. 2005; 29(12): 1539-1543.
28. Dedivitis RA, Pfuetzenreiter EG Jr., Nardi CEM, de Barbara ECD. Prospective study of clinical and laboratorial hypocalcemia after thyroid surgery. Braz J Otorhinolaryngol. 2010; 76(1): 71-77.
Review
For citations:
Lebedeva D.V., Ilyicheva E.A. Unstable Hemostasis and Specific Postoperative Complications (Literature Review). Acta Biomedica Scientifica. 2020;5(4):98-102. (In Russ.) https://doi.org/10.29413/ABS.2020-5.4.14