Morphological, Physiological and Genetic Characteristics of Populations of the Main Plague Host Rhombomys opimus Licht., 1823 in the Central Asian Desert Natural Focus of Plague
S. T. Nurtazin,
A. B. Shevtsov,
V. B. Lutsa,
E. M. Ramankulov,
Z. Z. Sayakova,
A. A. Abdrasilova,
A. S. Zhunusova,
N. P. Kabysheva,
A. K. Rysbekova,
V. P. Sadovskaya,
A. B. Eszhanov,
I. B. Utepova,
A. T. Berdibekov,
M. V. Kulemin,
Zh. U. Katuova,
B. B. Atshabar https://doi.org/10.29413/ABS.2019-4.5.22
Abstract
Revealed by morphological characters, physiological status, and genetic diversity of populations of the main plague host Rhombomys opimus Licht., 1823 in Central Asia desert natural focus is described.
Differences in the skull parameters of R. opimus from different populations were revealed. It’s shown that gerbils from Moyunkum are separate autonomous populations group. Samples from Moyunkum and Mangyshlak differed from other samples. In Balkhash-Alakol depression found two regional complexes: Pre-Balkhash and Dzungarian.
Study results of free amino acids level in R. opimus blood serum obtained by gas-liquid chromatography of blood sera from animals captured in different zones of Central Asian focus gave statistically significant differences. To determine genetic variability in ecological and geographical isolation of R. opimus populations the DNA was genotyped.
DNA samples analysis combined the studied gerbil from the desert focus into four clusters with eighteen haplotypes. R. opimus sequence analysis taking into account data from territories of Iran, Kazakhstan and China, clustered into three large clusters. First cluster combined the sequences of Kazakhstan and China samples, while great gerbil captured in Kazakhstan is located in a separate treasure. Second and third clusters include sequences of a great gerbil captured in Iran.
About the Authors
S. T. Nurtazin
Al-Farabi Kazakh National University of the Ministry of Education and Science of the Republic of Kazakhstan
Kazakhstan
Kazakhstan
Dr. Sc. (Med.), Professor at the Department of Biodiversity and Bioresources
Al-Farabi av. 71, Almaty 050040, Kazakhstan
A. B. Shevtsov
National Center for Biotechnology of the Ministry of Education and Science of the Republic of Kazakhstan
Kazakhstan
Kazakhstan
Cand. Sc. (Biol.), Head of the Laboratory of Applied Genetics
Kurgalzhinskoye Highway 13/5, Nur-Sultan 010000, Kazakhstan
V. B. Lutsa
National Center for Biotechnology of the Ministry of Education and Science of the Republic of Kazakhstan
Kazakhstan
Kazakhstan
Junior Research Officer at the Laboratory of Applied Genetics
Kurgalzhinskoye Highway 13/5, Nur-Sultan 010000, Kazakhstan
E. M. Ramankulov
National Center for Biotechnology of the Ministry of Education and Science of the Republic of Kazakhstan
Kazakhstan
Kazakhstan
PhD, Executive Director
Kurgalzhinskoye Highway 13/5, Nur-Sultan 010000, Kazakhstan
Z. Z. Sayakova
M. Aikimbaev’s Kazakh Scientific Centre for Quarantine and Zoonotic Diseases
Kazakhstan
Kazakhstan
Cand. Sc. (Biol.), Head of the Laboratory of Zoology and Parasitology with Museum and Insectarium
Zhakhanger str. 14 Almaty A35ROK3, Kazakhstan
A. A. Abdrasilova
M. Aikimbaev’s Kazakh Scientific Centre for Quarantine and Zoonotic Diseases
Kazakhstan
Kazakhstan
Head of the Laboratory of Molecular Diagnostics and Genetics
Zhakhanger str. 14 Almaty A35ROK3, Kazakhstan
A. S. Zhunusova
M. Aikimbaev’s Kazakh Scientific Centre for Quarantine and Zoonotic Diseases
Kazakhstan
Kazakhstan
Microbiologist at the Laboratory of Molecular Diagnostics and Genetics
Zhakhanger str. 14 Almaty A35ROK3, Kazakhstan
N. P. Kabysheva
M. Aikimbaev’s Kazakh Scientific Centre for Quarantine and Zoonotic Diseases
Kazakhstan
Kazakhstan
Microbiologist at the Laboratory of Molecular Diagnostics and Genetics
Zhakhanger str. 14 Almaty A35ROK3, Kazakhstan
A. K. Rysbekova
M. Aikimbaev’s Kazakh Scientific Centre for Quarantine and Zoonotic Diseases
Kazakhstan
Kazakhstan
Microbiologist at the Laboratory of Molecular Diagnostics and Genetics
Zhakhanger str. 14 Almaty A35ROK3, Kazakhstan
V. P. Sadovskaya
M. Aikimbaev’s Kazakh Scientific Centre for Quarantine and Zoonotic Diseases
Kazakhstan
Kazakhstan
Head of the Laboratory
Zhakhanger str. 14 Almaty A35ROK3, Kazakhstan
A. B. Eszhanov
M. Aikimbaev’s Kazakh Scientific Centre for Quarantine and Zoonotic Diseases
Kazakhstan
Kazakhstan
PhD, Leading Research Officer at the Laboratory of Zoology and Parasitology with Museum and Insectarium
Zhakhanger str. 14 Almaty A35ROK3, Kazakhstan
I. B. Utepova
M. Aikimbaev’s Kazakh Scientific Centre for Quarantine and Zoonotic Diseases
Kazakhstan
Kazakhstan
Cand. Sc. (Med.), Leading Research Officer at the Laboratory of Biosecurity and Biological Control
Zhakhanger str. 14 Almaty A35ROK3, Kazakhstan
A. T. Berdibekov
Taldykorgan Anti-Plague Station
Kazakhstan
Kazakhstan
Head
Nursultan Nazarbayev av. 104, 040000, Taldykorgan, Kazakhstan
M. V. Kulemin
Shymkent Anti-Plague Station
Kazakhstan
Kazakhstan
Head of the Laboratory of Epizootology and Prevention of Highly Infectious Diseases
M. Dulati str. 114, Shymkent 160013, Kazakhstan
Zh. U. Katuova
Aktyubinsk Anti-Plague Station
Kazakhstan
Kazakhstan
Zoologist
Kaidauyl Batyr str. 10, Zarechny-2, Aktobe 030000, Kazakhstan
B. B. Atshabar
M. Aikimbaev’s Kazakh Scientific Centre for Quarantine and Zoonotic Diseases
Kazakhstan
Kazakhstan
Dr. Sc. (Med.), Chief Research Officer
Zhakhanger str. 14 Almaty A35ROK3, Kazakhstan
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Review
For citations:
Nurtazin S.T., Shevtsov A.B., Lutsa V.B., Ramankulov E.M., Sayakova Z.Z., Abdrasilova A.A., Zhunusova A.S., Kabysheva N.P., Rysbekova A.K., Sadovskaya V.P., Eszhanov A.B., Utepova I.B., Berdibekov A.T., Kulemin M.V., Katuova Zh.U., Atshabar B.B. Morphological, Physiological and Genetic Characteristics of Populations of the Main Plague Host Rhombomys opimus Licht., 1823 in the Central Asian Desert Natural Focus of Plague. Acta Biomedica Scientifica. 2019;4(5):139-143. (In Russ.) https://doi.org/10.29413/ABS.2019-4.5.22
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