Preview

Acta Biomedica Scientifica

Расширенный поиск

Эмоциональная дизрегуляция как фактор психосоматических нарушений при депрессии и кардиоваскулярной патологии (аналитический обзор иностранной литературы)

https://doi.org/10.29413/ABS.2019-4.1.13

Полный текст:

Аннотация

В обзоре представлены данные нарушений когнитивных процессов эмоциональной регуляции, которые являются результатом взаимодействия активности префронтальной коры и эмоциональных центров, в качестве важнейшего патогенетического звена психосоматических отношений депрессивных и сердечно-сосудистых заболеваний. Нейроанатомическим субстратом эмоциональной регуляции являются связи эмоциональных и когнитивных процессов, которые осуществляются посредством двунаправленных нейрональных взаимодействий между неокортексом и эмоциональными центрами. Эта связь позволяет эмоциональным центрам модулировать кортикальную активность, а когнитивным центрам через нисходящие кортикальные влияния – модулировать процессинг эмоций. В настоящее время подтверждены прямые и непрямые связи фронтальной коры с центрами вегетативной нервной системы и её возбуждающими симпатическими и ингибирующими парасимпатическими влияниями. Патогенетические звенья эмоциональной дизрегуляции включают нейробиологические и когнитивные (руминации, фиксация на негативной информации) процессы. Патофизиологические механизмы депрессии и сердечно-сосудистых заболеваний имеют общие звенья – дизрегуляция метаболических, иммунологических и гипоталамус-гипофиз-адреналовой систем. Наклонность к негативному эмоциональному реагированию, преобладание негативных эмоций и алекситимия (низкая осознанность эмоции) выделяются в качестве предикторов развития как сердечно-сосудистых заболеваний, так и депрессии. При коморбидности с депрессией установлено снижение качества жизни и повышение смертности от сердечно-сосудистых заболеваний, даже с учётом таких известных биологических факторов риска, как высокий уровень холестерина и повышенное артериальное давление. Исследования, направленные на изучение типологии и значения эмоциональной дизрегуляции при различных формах психопатологических расстройств, в аспекте коморбидности и психосоматических отношений с соматическими заболеваниями могут оказаться плодотворными в плане поиска новых подходов к диагностике и терапии

Об авторах

В. С. Собенников
ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России
Россия
Собенников Василий Самуилович – доктор медицинских наук, профессор, заведующий кафедрой психиатрии и медицинской психологии


Е. В. Винокуров
ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России; ФГБНУ «Научный центр проблем здоровья семьи и репродукции человека»
Россия
Винокуров Евгений Вячеславович – кандидат медицинских наук, научный сотрудник лаборатории психонейросоматической патологии детского возраста


Л. В. Рычкова
ФГБНУ «Научный центр проблем здоровья семьи и репродукции человека»
Россия
Рычкова Любовь Владимировна – доктор медицинских наук, профессор РАН, директор


В. В. Собенникова
ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России
Россия
Собенникова Вероника Васильевна – кандидат медицинских наук, ассистент кафедры психиатрии и медицинской психологии


Список литературы

1. Slepecky M, Kotianova A, Prasko J, Majercak I, et al. Which psychological, psychophysiological, and anthropometric factors are connected with life events, depression, and quality of life in patients with cardiovascular disease. Neuropsychiatr Dis Treat. 2017; 2017(13): 2093-2104. doi: 10.2147/NDT.S141811

2. Everson-Rose SA, Lewis TT. Psychosocial factors and cardiovascular diseases. Ann Rev Public Health. 2005; 26: 469-500. doi. 10.1146/annurev.publhealth.26.021304.144542

3. Rozanski A, Blumenthal JA, Kaplan J. Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. Circulation. 1999; 99(16): 2192-2217. doi: 10.1161/01.CIR.99.16.2192

4. Abelson JL, Liberzon I, Young EA, Khan S. Cognitive modulation of the endocrine stress response to a pharmacological challenge in normal and panic disorder subjects. Arch Gen Psychiatr. 2005; 62(6): 668-675. doi. 10.1001/archpsyc.62.6.668

5. Dunbar H, Flanders J, Foundation Josiah Macy. Emotions and bodily changes: a survey of literature on psychosomatic interrelationships, 1910–1933; 2nd ed. New York: Pub. for the Josiah Macy, Jr., Foundation by Columbia University Press; 1938.

6. Compare A, Zarbo C, Manzoni GM, Castelnuovo G, Baldassari E, Bonardi A, et al. Social support, depression, and heart disease: a ten year literature review. Front Psychol. 2013; 4: 384. doi. 10.3389/fpsyg.2013.00384

7. Smith PJ, Blumenthal JA. Psychiatric and behavioral aspects of cardiovascular disease: epidemiology, mechanisms, and treatment. Revista Espanola De Cardiologia. 2011; 64(10), 924-933. doi. 10.1016/j.recesp.2011.06.003

8. Van Dooren FE, Nefs G, Schram MT, Verhey FR, Denollet J, Pouwer F. Depression and risk of mortality in people with diabetes mellitus: a systematic review and meta-analysis. PloS One. 2013; 8(3): e57058. doi: 10.1371/journal.pone.0057058

9. Pizzi C, Manzoli L, Mancini S, Bedetti G, Fontana F, Costa GM. Autonomic nervous system, inflammation and preclinical carotid atherosclerosis in depressed subjects with coronary risk factors. Atherosclerosis. 2010; 212(1): 292-298. doi. 10.1016/j.atherosclerosis.2010.04.038

10. Smith TW, Ruiz JM. Psychosocial influences on the development and course of coronary heart disease: current status and implications for research and practice. J Consult Clin Psychol. 2002; 70(3): 548-568. doi: 10.1037/0022-006X.70.3.548

11. Suls J, Bunde J. Anger, anxiety, and depression as risk factors for cardiovascular disease: the problems and implications of overlapping affective dispositions. Psychol Bull. 2005; 131(2): 260-300. doi: 10.1037/0033-2909.131.2.260

12. Asimakopoulou KG, Skinner TC, Spimpolo J, Marsh S, Fox C. Unrealistic pessimism about risk of coronary heart disease and stroke in patients with type 2 diabetes. Patient Educ Couns. 2008; 71(1): 95-101. doi: 10.1016/j.pec.2007.12.007

13. Janszky I, Ahnve S, Lundberg I, Hemmingsson T. Earlyonset depression, anxiety, and risk of subsequent coronary heart disease: 37-year follow-up of 49,321 young Swedish men. J Am Coll Cardiol. 2010; 56(1), 31-37. doi: 10.1016/j.jacc.2010.03.033

14. Valkamo M, Hintikka J, Honkalampi K, Niskanen L, Koivumaa-Honkanen H, Viinamäki H. Alexithymia in patients with coronary heart disease. J Psychosom Res, 50(3), 125-130. doi: 10.1016/S0022-3999(00)00209-9

15. Scherrer JF, Xian H, Bucholz KK, Eisen SA, Lyons MJ, Goldberg J, et al. A twin study of depression symptoms, hypertension, and heart disease in middle-aged men. Psychosom Med. 2003; 65: 548-557.

16. Musselman DL, Evans DL, Nemeroff CB. The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Arch Gen Psychiatr. 1998; 55(7): 580-592. doi: 10.1001/ archpsyc.55.7.580

17. Berenbaum H, Raghavan C, Le H-N, Vernon LL, Gomez JJ. A taxonomy of emotional disturbances. Clin Psychol Sci Pract. 2003; 10(2): 206-226. doi: 10.1093/clipsy.bpg011

18. Mennin D, Farach F. Emotion and evolving treatments for adult psychopathology. Clin Psychol Sci Pract. 2007; 14(4): 329-352. doi: 10.1111/j.1468-2850.2007.00094.x

19. Aldao A, Gee GG, De Los Reyes A, Seager I. Emotion regulation as a transdiagnostic factor in the development of internalizing and externalizing psychopathology: Current and future directions. Dev Psychopathol. 2016; 28(4 Pt 1): 927-946. doi: 10.1017/S0954579416000638

20. Bradley B, DeFife JA, Guarnaccia C, Phifer J, Fani N, Ressler KJ, et al. Emotion dysregulation and negative affect: association with psychiatric symptoms. J Clin Psychiatr. 2011; 72(5), 685-691. doi: 10.4088/JCP.10m06409blu

21. Sarason IG, Johnson JH, Siegel JM. Assessing the impact of life changes: development of the Life Experiences Survey. J Consult Clin Psychol. 1978; 46(5): 932-946.

22. Schwartz D, Proctor LJ. Community violence exposure and children’s social adjustment in the school peer group: the mediating roles of emotion regulation and social cognition. J Consult Clin Psychol. 2000; 68(4): 670–683.

23. Gross JJ. Antecedent- and response-focused emotion regulation: divergent consequences for experience, expression, and physiology. J Pers Soc Psychol. 1998; 74: 224-237.

24. Compare A, Zarbo C, Shonin E, Van Gordon W, Marconi C. Emotional regulation and depression: a potential mediator between heart and mind. cardiovascular psychiatry and neurology. 2014; 2014: 324374. doi: 10.1155/2014/324374

25. Goldin PR, McRae K, Ramel W, Gross JJ. The neural bases of emotion regulation: reappraisal and suppression of negative emotion. Biol Psychiatr. 2008; 63(6): 577-586. doi: 10.1016/j.biopsych.2007.05.031

26. Gratz KL, Roemer L. Multidimensional assessment of emotion regulation and dysregulation: development, factor structure, and initial validation of the difficulties in emotion regulation scale. J Psychopathol Behav Assess. 2008; 30(4): 315-315. doi: 10.1007/ s10862-008-9102-4

27. Cole PM, Hall SE. Emotion dysregulation as a risk factor for psychopathology. In: Beauchaine TP, Hinshaw SP. (Eds.) Child and Adolescent Psychopathology. Princeton, N.J.: John Wiley&Sons; 2008: 265-287.

28. Kreatsoulas C, Anand SS. The impact of social determinants on cardiovascular disease. Canadian J Cardiol. 2010; 26(Suppl C): 8C-13C. doi: 10.1016/S0828-282X(10)71075-8

29. Zoccola PM, Dickerson SS, Zaldivar FP. Rumination and cortisol responses to laboratory stressors. Psychosom Med. 2008; 70(6): 661-667. doi: 10.1097/PSY.0b013e31817bbc77

30. Penza-Clyve S, Zeman J. Initial validation of the Emotion Expression Scale for Children (EESC). J Clin Child Adolesc Psychol. 2002; 31(4): 540-547. doi: 10.1207/153744202320802205

31. Salovey P, Stroud LR, Woolery A, Epel ES. Perceived emotional intelligence, stress reactivity, and symptom reports: further explorations using the trait meta-mood scale. Psychol Health. 2002; 17: 611-627. doi: 10.1080/08870440290025812

32. Sifneos PE. The prevalence of ’alexithymic’ characteristics in psychosomatic patients. Psychother Psychosom. 1973; 22: 255- 262. doi: 10.1159/000286529

33. Simons JS, Carey KB. An affective and cognitive model of marijuana and alcohol problems. Addict Behav. 2006; 31(9): 1578- 1592. doi: 10.1016/j.addbeh.2005.12.004

34. Dragoş D, Tănăsescu MD. The critical role of psychosomatics in promoting a new perspective upon health and disease. J Med Life. 2009; 2(4): 343-349.

35. Taylor GJ. Recent developments in alexithymia theory and research. Canadian J Psychiatr. 2000; 45(2): 134-142. doi: 10.1177/070674370004500203

36. Taylor GJ, Bagby RM. New trends in alexithymia research. Psychother Psychosom. 2004; 73: 68-77. doi: 10.1159/000075537

37. Grabe HJ, Schwahn C, Barnow S, Spitzer C, John U, Freyberger HJ, et al. Alexithymia, hypertension, and subclinical atherosclerosis in the general population. J Psychosom Res. 2010; 68: 139-147. doi: 10.1016/j.jpsychores.2009.07.015

38. Lumley MA, Neely LC, Burger AJ. The assessment of alexithymia in medical settings: implications for understanding and treating health problems. J Personality Assess. 2007; 89(3): 230-246. doi: 10.1080/00223890701629698

39. Lumley MA, Radcliffe AM, Macklem DJ, Mosley-Williams A, Leisen JC, Huffman JL, et al. Alexithymia and pain in three chronic pain samples: comparing Caucasians and African Americans. Pain Med. 2005; 6: 251-261. doi: 10.1111/j.1526-4637.2005.05036.x

40. Porcelli P, De Carne M, Todarello O. Prediction of treatment outcome of patients with functional gastrointestinal disorders by the diagnostic criteria for psychosomatic research. Psychother Psychosom. 2004; 73: 166-173. doi: 10.1159/000076454

41. Taylor GJ, Bagby RM, Parker JD. The alexithymia construct. A potential paradigm for psychosomatic medicine. Psychosomatics. 1991; 32(2): 153-164. doi: 10.1016/S0033-3182(91)72086-0

42. Nakao M, Barsky AJ, Kumano H, Kuboki T. Relationship between somatosensory amplification and alexithymia in a Japanese psychosomatic clinic. Psychosomatics. 2002; 43(1): 55-60. doi: 10.1176/appi.psy.43.1.55

43. Kano M, Fukudo S. The alexithymic brain: the neural pathways linking alexithymia to physical disorders. BioPsychoSocial Medicine. 2013; 7: 1. doi: 10.1186/1751-0759-7-1

44. Duschek S, Dietel A, Schandry R, del Paso GA. Increased sensitivity to heat pain in chronic low blood pressure. Eur J Pain. 2009; 13(1): 28-34. doi: 10.1016/j.ejpain.2008.02.007

45. McCubbin JA, Helfer SG, Switzer FS 3rd, Galloway C, Griffith WV. Opioid analgesia in persons at risk for hypertension. Psychosom Med, 2006; 68(1): 116-120. doi: 10.1097/01. psy.0000195742.24850.79

46. Ghione S. Hypertension-associated hypalgesia. Evidence in experimental animals and humans, pathophysiological mechanisms, and potential clinical consequences. Hypertension. 1996; 28(3): 494-504. doi: 10.1161/01.HYP.28.3.494

47. Nyklícek I, Vingerhoets JJ, Van Heck GL. Hypertension and objective and self-reported stressor exposure: a review. J Psychosom Res. 1996; 40(6): 585-601. doi: 10.1016/0022- 3999(95)00647-8

48. Nyklícek I, Vingerhoets AJJM, Van Heck GL. Hypertension and appraisal of physical and psychological stressors. J Psychosom Res. 2001; 50: 237-244.

49. Pury CL, McCubbin JA, Helfer SG, Galloway C, McMullen LJ. Elevated resting blood pressure and dampened emotional response. Psychosom Med. 2004; 66(4): 583-587. doi: 10.1097/01. psy.0000130490.57706.88

50. McCubbin JA, Merritt MM, Sollers JJ 3rd, Evans MK, Zonderman AB, Lane RD, et al. Cardiovascular-emotional dampening: the relationship between blood pressure and recognition of emotion. Psychosom Med. 2011; 73(9): 743-750. doi: 10.1097/ PSY.0b013e318235ed55

51. Campbell-Sills L, Barlow DH, Brown TA, Hofmann SG. Acceptability and suppression of negative emotion in anxiety and mood disorders. Emotion. 2006; 6(4): 587-595. doi: 10.1037/1528- 3542.6.4.587

52. Kashdan TB, Barrios V, Forsyth JP, Steger MF. Experiential avoidance as a generalized psychological vulnerability: comparisons with coping and emotion regulation strategies. Behav Res Ther. 2006; 44(9): 1301-1320. doi: 10.1016/j.brat.2005.10.003

53. Gross JJ, Richards JM, John OP. Emotion regulation in everyday life. In: Snyder DK, Simpson J, Hughes JN. (Eds.) Emotion Regulation in Couples and Families: Pathways to Dysfunction and Health. Washington: American Psychological Association; 2006: 13-35. doi: 10.1037/11468-001

54. Salters-Pedneault K, Tull MT, Roemer L. The role of avoidance of emotional material in the anxiety disorders. Appl Prev Psychol. 2004; 11(2): 95-114. doi: 10.1016/j.appsy.2004.09.001

55. Moore SA, Zoellner LA, Mollenholt N. Are expressive suppression and cognitive reappraisal associated with stress-related symptoms? Behav Res Ther. 2008; 46(9): 993-1000. doi: 10.1016/j. brat.2008.05.001

56. Akiskal KK, Akiskal HS. The theoretical underpinnings of affective temperaments: implications for evolutionary foundations of bipolar disorder and human nature. J Affect Disord. 2005; 85(1-2): 231-239. doi: 10.1016/j.jad.2004.08.002

57. Bouchard TJ Jr. Genes, environment, and personality. Science. 1994; 264(5166): 1700-1701. doi: 10.1126/science.8209250

58. Vlachopoulos C, Aznaouridis K, O’Rourke MF, Safar ME, Baou K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis. Eur Heart J. 2010; 31(15): 1865-1871. doi: 10.1093/eurheartj/ehq024

59. Eory A, Rozsa S, Torzsa P, Kalabay L, Gonda X, Rihmer Z. Affective temperaments contribute to cardiac complications in hypertension independently of depression. Psychother Psychosom. 2014; 83: 187-189. doi: 10.1159/000357364

60. Korosi B, Laszlo A, Tabak A, Batta D, Lenart L, Fekete A, et al. The impact of currently recommended antihypertensive therapy on depression and other psychometric parameters: preliminary communication. Neuropsychopharmacologia Hungarica. 2017; 19: 11-22.

61. László A, Tabák Á, Kőrösi B, Eörsi D, Torzsa P, Cseprekál O, et al. Association of affective temperaments with blood pressure and arterial stiffness in hypertensive patients: a cross-sectional study. BMC Cardiovasc Disord. 2016; 16: 158. doi: 10.1186/s12872- 016-0337-9

62. KuKupper N, Pedersen SS, Höfer S, Saner H, Oldridge N, Denollet J. Cross-cultural analysis of type D (distressed) personality in 6222 patients with ischemic heart disease: a study from the International HeartQoL Project. Int J Cardiol. 2013; 166(2): 327-333. doi: 10.1016/j.ijcard.2011.10.084

63. Anestis MD, Peterson CB, Bardone-Cone AM, Klein MH, Mitchell JE, Crosby RD, et al. Affective lability and impulsivity in a clinical sample of women with bulimia nervosa: the role of affect in severely dysregulated behavior. Int J Eating Disorders. 2009; 42(3): 259-266. doi: 10.1002/eat.20606

64. Coccaro EF, Harvey PD, Kupsaw-Lawrence E, Herbert JL, Bernstein DP. Development of neuropharmacologically based behavioral assessments of impulsive aggressive behavior. J Neuropsychiatr Clin Neurosci. 1991; 3(2): S44-S51.

65. Ebner-Priemer UW, Kuo J, Kleindienst N, Welch SS, Reisch T, Reinhard I, et al. State affective instability in borderline personality disorder assessed by ambulatory monitoring. Psychol Med. 2007; 37(7): 961-970. doi: 10.1017/S0033291706009706

66. Simons JS, Carey KB. An affective and cognitive model of marijuana and alcohol problems. Addict Behav. 2006; 31(9): 1578- 1592. doi: 10.1016/j.addbeh.2005.12.004

67. Turvey CL, Conwell Y, Jones MP, Phillips C, Simonsick E, Pearson JL, et al. Risk factors for late-life suicide: a prospective, community-based study. Am J Geriatr Psychiatr. 2002; 10: 398-406. doi: 10.1097/00019442-200207000-00006

68. Borkovec TD, Ray WJ, Stober J. Worry: a cognitive phenomenon intimately linked to affective, physiological, and interpersonal behavioral processes. Cogn Ther Res. 1998; 22(6): 561-576. doi: 10.1023/A:1018790003416

69. Dardiotis E, Giamouzis G, Mastrogiannis D, Vogiatzi C, Skoularigis J, Triposkiadis F, et al. Cognitive impairment in heart failure. Cardiol Res Pract. 2012; 2012, 595821. doi: 10.1155/2012/595821

70. Hovland A, Pallesen S, Hammar Å, Hansen AL, Thayer JF, Tarvainen MP. The relationships among heart rate variability, executive functions, and clinical variables in patients with panic disorder. Int J Psychophysiol. 2012; 86(3): 269-275. doi: 10.1016/j. ijpsycho.2012.10.004

71. Gillie BL, Thayer JF. Individual differences in resting heart rate variability and cognitive control in posttraumatic stress disorder. Front Psychol. 2014; 5: 758. doi: 10.3389/fpsyg.2014.00758

72. Bartczak D, Szymański Ł, Bodera P, Stankiewicz W. Psychoneuroimmunological aspects of cardiovascular diseases: a preliminary report. Centr Eur J Immunol. 2016; 41(2): 209-216. doi: 10.5114/ceji.2016.60996


Для цитирования:


Собенников В.С., Винокуров Е.В., Рычкова Л.В., Собенникова В.В. Эмоциональная дизрегуляция как фактор психосоматических нарушений при депрессии и кардиоваскулярной патологии (аналитический обзор иностранной литературы). Acta Biomedica Scientifica. 2019;4(1):87-92. https://doi.org/10.29413/ABS.2019-4.1.13

For citation:


Sobennikov V.S., Vinokurov E.V., Rychkova L.V., Sobennikova V.V. Emotional Dysregulation as a Factor of Psychosomatic Disturbances in Depression and Cardiovascular Pathology (Analytical Review of Foreign Literature). Acta Biomedica Scientifica. 2019;4(1):87-92. (In Russ.) https://doi.org/10.29413/ABS.2019-4.1.13

Просмотров: 893


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 2541-9420 (Print)
ISSN 2587-9596 (Online)