Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players
Abstract
The dynamics of the level of malondialdehyde (MDA), activity of superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase was investigated in blood serum of professional rugby players during one year training and competitive season. The MDA level significantly exceeds control level during all the year. The maximum of MDA concentration is registered at the end of competition period and isn't restored during the period of rest. The SOD and CAT activity is significantly reduced and doesn't return to control levels during the year. These changes prove chronic decompensation in the antioxidant defense system. In athletes glutathione-S-transferase is the leading enzyme realizing protection against reactive oxygen species in blood serum of sportsmen. Compensatory increase of its activity is 660 % in reference to the level of control group.
About the Authors
K. P. Bazarin
Scientific Institute of Medical Problems of the North SB RAMS
Russian Federation
Russian Federation
N. M. Titova
Siberian Federal University
Russian Federation
Russian Federation
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Review
For citations:
Bazarin K.P., Titova N.M. Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players. Acta Biomedica Scientifica. 2014;(3):9-13. (In Russ.)
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