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Acta Biomedica Scientifica

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Взаимоотношения систем комплемента, Toll-подобных рецепторов, антигенов CD и цитокинов в норме и при патологиях. Обзор

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Аннотация

В обзоре публикаций рассмотрены защитные системы врожденного иммунитета млекопитающих: комплемента, Toll-подобных рецепторов, антигенов CD, других паттерн-распознающих рецепторов и молекул. Приведены данные о таких аспектах указанных систем, как кооперация и синергизм; инициация, переключение, амплификация и терминация путей; стратегии патогенов и контрстратегии хозяина; подходы к созданию адресных механизмов лечения болезней науровне метаболомных узловых коммуникаций; перспективы разработки комбинированных системных препаратов для медицины.

Об авторах

М. В. Лахтин
ФБУН «МНИИЭМ им. Г.Н. Габричевского» Роспотребнадзора
Россия


В. М. Лахтин
ФБУН «МНИИЭМ им. Г.Н. Габричевского» Роспотребнадзора
Россия


С. С. Афанасьев
ФБУН «МНИИЭМ им. Г.Н. Габричевского» Роспотребнадзора
Россия


В. А. Алешкин
ФБУН «МНИИЭМ им. Г.Н. Габричевского» Роспотребнадзора
Россия


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Для цитирования:


Лахтин М.В., Лахтин В.М., Афанасьев С.С., Алешкин В.А. Взаимоотношения систем комплемента, Toll-подобных рецепторов, антигенов CD и цитокинов в норме и при патологиях. Обзор. Acta Biomedica Scientifica. 2015;(6):62-66.

For citation:


Lakhtin M.V., Lakhtin V.M., Afanasiev S.S., Aleshkin V.A. Interrelation between the system of complement, Tolllike receptors, CD antigens and cytokines in normal and pathological condition. Review. Acta Biomedica Scientifica. 2015;(6):62-66. (In Russ.)

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