IMMUNOLOGICAL MONITORING OF THE INFLUENZA VIRUS A SUBTYPE H5 AND H7 DISTRIBUTION IN SOUTH OF CENTRAL SIBERIA

Abstract

For the first time in the south of the Central Siberia carried out large-scale study of wild and synanthropic birds for the presence of influenza A viruses. Along with the traditional methods of laboratory study of pathogens in Merskey's reaction and. PCR carried out ornithological research in areas of high concentrations of birds and. flyways. Also studied the long-term dynamics of isolation of positive samples containing specific antibody to influenza virus A subtypes H5 and. H7 and. genomic RNA of these subtypes. It was found that infection and. reinfection. of birds by avian influenza doesn't take place only during the wintering grounds, but also the breeding season in the water keepings of the south of the Central Siberia. Chicks are actively involved in the epizootic process in July, when transovarialy transmitted maternal antibodies disappear. Because of the peak interval of positive samples selection in Merskey's reaction and. PCR is 3 years, it is possible to organize an immunological monitoring followed by preventive programs development of birds deaths.