Перспективы создания антимикробных препаратов на основе наночастиц меди и оксидов меди

Распространение полирезистентных к современным антимикробным препаратам штаммов микроорганизмов по-прежнему остаётся актуальной проблемой лечения и профилактики инфекционных заболеваний и общественного здравоохранения в целом.
В настоящее время активно изучается возможность применения нанопрепаратов металлов в различных областях медицины. Наночастицы металлов и оксидов металлов являются перспективными антимикробными агентами и вызывают растущий интерес благодаря своей эффективности. Металлические частицы меди в наномасштабе продемонстрировали высокую антимикробную активность против различных видов грамположительных и грамотрицательных бактерий, а также грибков. Учитывая потенциал наночастиц меди и её оксидов в противомикробной терапии, мы представляем обзор современного состояния исследований, связанных с их антимикробными свойствами, рассмотрением механизмов действия, ключевых факторов, влияющих на антимикробную активность, в том числе полимерной матрицы. Рассмотрены вопросы токсичности и устойчивости к меди. Показано преимущество наночастиц меди и оксидов меди перед другими металлическими наночастицами.
Обобщённые в этом обзоре исследования показали перспективность наночастиц меди в создании новых антимикробных препаратов, которые в будущем могут быть использованы для контроля, профилактики и лечения различных заболеваний.

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