Relationship of coronary heart disease and comorbide dental background
https://doi.org/10.29413/ABS.2021-6.4.8
Abstract
Cardiovascular disease has serious economic and social consequences that affect people, health systems and societies around the world. Ischemic heart disease is one of the main global causes of death of the population, and its growth is predicted in the coming years. This fact continues to be of serious concern to health, social and economic services. Cardiovascular disease remains the most common cause of death, and age-standardized rates are higher for men than for women. Cardiovascular comorbidity increases significantly with age.
The combination of ischemic heart disease and comorbid pathology is noted in cancer incidence, bronchial asthma, non-alcoholic fatty liver disease, type 2 diabetes mellitus, chronic obstructive pulmonary disease, periodontal disease, etc. It is necessary to analyze the existing disease with past diseases, risk factors and predictors available in the patient. The presence of concomitant diseases quite often requires additional diagnostic methods and changes in the tactics of treating coronary heart disease due to the fact that some of them are a contraindication to the use of certain groups of drugs. Periodontal disease includes a wide range of inflammatory conditions that affect the supporting structures of the teeth, which can lead to tooth loss and contribute to systemic inflammation. Periodontal disease is associated with several systemic diseases, one of which is coronary artery disease. It is imperative that clinicians understand the link between periodontal disease and cardiovascular disease. Comprehensive treatment of periodontitis and restoration of a healthy periodontium can help reduce overall inflammation in the body and reduce the risks of coronary heart disease.
About the Authors
V. A. Khaptanova
Irkutsk State Medical University
Russian Federation
Russian Federation
Cand. Sc. (Med.), Associate Professor at the Department of Polyclinic Therapy and General Medical Practice
Krasnogo Vosstaniya str. 1, 664003 Irkutsk, Russian Federation
A. D. Golmenko
Irkutsk State University
Russian Federation
Russian Federation
Dr. Sc. (Med.), Professor at the Department of Psychodiagnostics and Practical Psychology
Karla Marksa str. 1, 664003 Irkutsk, Russian Federation
A. Yu. Khaptanov
Irkutsk State Medical University
Russian Federation
Russian Federation
Resident at the Department of Therapeutic Dentistry
Krasnogo Vosstaniya str. 1, 664003 Irkutsk, Russian Federation
D. Yu. Gamayunov
Irkutsk State Medical University
Russian Federation
Russian Federation
Student
Krasnogo Vosstaniya str. 1, 664003 Irkutsk, Russian Federation
References
1. Timmis A, Townsend N, Gale CP, Torbica A, Lettino M, Petersen SE, et al. European Society of Cardiology: Cardiovascular Disease Statistics 2019. Eur Heart J. 2020; 41(1): 12-85. doi: 10.1093/eurheartj/ehz859
2. Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, Chang AR, Cheng S, et al. Heart disease and stroke statistics – 2018 update: A report from the American Heart Association. Circulation. 2018; 137(12): e67-e492. doi: 10.1161/CIR.0000000000000558
3. Nowbar AN, Gitto M, Howard JP, Francis DP, Al-Lamee R. Mortality from ischemic heart disease. Circ Cardiovasc Qual Outcomes. 2019; 12(6): e005375. doi: 10.1161/CIRCOUTCOMES.118.005375
4. Yashchenko SG, Kozulya SV, Rybalko SYu, Butyrskaya IB. Diseases of the circulatory system in the Republic of Crimea: Morbidity, mortality, economic losses. Tavricheskiy mediko-biologicheskiy vestnik. 2019; 22(3): 78-85. (In Russ.).
5. Shin J, Ham D, Shin S, Choi SK, Paik H-Y, Joung H. Effects of lifestyle-related factors on ischemic heart disease according to body mass index and fasting blood glucose levels in Korean adults. PLoS ONE. 2019; 14(5): e0216534. doi: 10.1371/journal.pone.0216534
6. Boytsov SA, Demkina AE, Oshchepkova EV, Dolgusheva YA. Progress and problems of practical cardiology in Russia at the present stage. Kardiologiia. 2019; 59(3): 53-59. doi: 10.18087/cardio.2019.3.10242
7. Huxley RR, Woodward M. Cigarette smoking as a risk factor for coronary heart disease in women compared with men: A systematic review and meta-analysis of prospective cohort studies. Lancet. 2011; 378(9799): 1297-1305. doi: 10.1016/S0140-6736(11)60781-2
8. Campbell SC, Moffatt RJ, Stamford BA. Smoking and smoking cessation – the relationship between cardiovascular disease and lipoprotein metabolism: A review. Atherosclerosis. 2008; 201(2): 225-235. doi: 10.1016/j.atherosclerosis.2008.04.046
9. Cullen P, Schulte H, Assmann G. Smoking, lipoproteins and coronary heart disease risk: Data from the Münster Heart Study (PROCAM). Eur Heart J. 1998; 19(11): 1632-1641. doi: 10.1053/euhj.1998.1086
10. Brien SE, Ronksley PE, Turner BJ, Mukamal KJ, Ghali WA. Effect of alcohol consumption on biological markers associated with risk of coronary heart disease: Systematic review and meta-analysis of interventional studies. BMJ. 2011; 342: d636. doi: 10.1136/bmj.d636
11. Ronksley PE, Brien SE, Turner BJ, Mukamal KJ, Ghali WA. Association of alcohol consumption with selected cardiovascular disease outcomes: A systematic review and meta-analysis. BMJ. 2011; 342: d671. doi: 10.1136/bmj.d671
12. Gregg EW, Cheng YJ, Cadwell BL, Imperatore G, Williams DE, Flegal KM, et al. Secular trends in cardiovascular disease risk factors according to body mass index in US adults. JAMA. 2005; 293(15): 1868-1874. doi: 10.1001/jama.293.15.1868
13. Mente A, de Koning L, Shannon HS, Anand SS. A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease. Arch Intern Med. 2009; 169(7): 659-669. doi: 10.1001/archinternmed.2009.38
14. Yusuf S, Hawken S, Ôunpuu S, Dans T, Avezum A, Lanas F, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study. Lancet. 2004; 364(9438): 937-952. doi: 10.1016/S0140-6736(04)17018-9
15. Stampfer MJ, Hu FB, Manson JE, Rimm EB, Willett WC. Primary prevention of coronary heart disease in women through diet and lifestyle. New Engl J Med. 2000; 343(1): 16-22. doi: 10.1056/NEJM200007063430103
16. Sattelmair J, Pertman J, Ding EL, Kohl HW, Haskell W, Lee I-M. Dose response between physical activity and risk of coronary heart disease: A meta-analysis. Circulation. 2011; 124(7): 789-795. doi: 10.1161/CIRCULATIONAHA.110.010710
17. Ko DT, Wijeysundera HC, Udell JA, Vaccarino V, Austin PC, Guo H, et al. Traditional cardiovascular risk factors and the presence of obstructive coronary artery disease in men and women. Can J Cardiol. 2014; 30(7): 820-826. doi: 10.1016/j.cjca.2014.04.032
18. Noda H, Iso H, Saito I, Konishi M, Inoue M, Tsugane S. The impact of the metabolic syndrome and its components on the incidence of ischemic heart disease and stroke: The Japan public health center-based study. Hypertens Res. 2009; 32(4): 289-298. doi: 10.1038/hr.2009.14
19. Flegal KM.Body-mass index and all-cause mortality. Lancet. 2017; 389(10086): 2284-2285. doi: 10.1016/S0140-6736(17)31437-X
20. Federal Service of State Statistics. Healthcare in Russia 2019: Statistical collection. Moscow; 2019: 170. (In Russ.).
21. Russian Society of Cardiology. Clinical guidelines. Stable ischemic heart disease. 2020: 114. (In Russ.).
22. Popov AP, Soprunov NI. Heart disease: Ischemic heart disease (IHD). Science Bulletin. 2019; 42(11): 49-53. (In Russ.).
23. Zhelikhazheva MV. The problem of comorbidity in patients with coronary heart disease and concomitant oncological pathology. Russian Journal of Thoracic and Cardiovascular Surgery. 2019; 61(6): 485-490. (In Russ.). doi: 10.24022/0236-2791-2019-61-6-485-490
24. Vertkin AL, Rumyantsev MA, Skotnikov AS. Comorbidity in clinical practice. Part 1. The Russian Archives of Internal Medicine. 2011; (1): 16-20. (In Russ.). doi: 10.20514/2226-6704-2011-0-1-16-20
25. Melikhova SP, Shevtsova VI, Zuikova AA, Kotova YuA. Study of comorbid pathology in type 2 diabetes mellitus as a complication of metabolic syndrome. The Russian Archives of Internal Medicine. 2018; 8(5): 366-371. (In Russ.). doi: 10.20514/2226-6704-2018-0-5-366-371
26. Grigoryeva NY, Ilyushina TP, Kolosova KS, Koroleva NB, Streltsova AA, Soloveva DV. Clinical course of coronary heart disease concomitant with asthma. The Russian Archives of Internal Medicine. 2020; 10(2): 131-138. (In Russ.). doi: 10.20514/2226-6704-2020-10-2-131-138
27. Oganov RG, Simanenkov VI, Bakulin IG, Bakulina NV, Barbarash OL, Boytsov SA, et al. Comorbid pathology in clinical practice. Diagnostic and treatment algorithms. Cardiovascular Therapy and Prevention. 2019; 18(1): 5-66. (In Russ.). doi: 10.15829/1728-8800-2019-1-5-66
28. Gendlin GE, Emelina EI, Nikitin IG, Vasyuk YuA. Modern view of the cardiotoxicity of cancer chemotherapy, including anthracycline antibiotics. Russian Journal of Cardiology. 2017; (3): 145-154. (In Russ.). doi: 10.15829/1560-4071-2017-3-145-154
29. Sergeeva VV, Polonskaya II. Medical and social aspects of the influence of comorbid pathology on the rehabilitation of patients with coronary heart disease after coronary artery bypass grafting. Medical Education Today. 2019; 1(5): 20-33. (In Russ.).
30. Kutsenko MA. The paradigm of comorbidity: Syntropy of COPD and ischemic heart disease. Chelovek i lekarstvo. 2015; 57(11): 26-30. (In Russ.).
31. Khasanova ZI, Makarova NV. Coronary artery disease. Analysis of the incidence of acute coronary heart disease in the adult population, as well as mortality from them in the Russian Federation for 2012. Avicenna. 2020; 67: 20-23. (In Russ.).
32. Einarson TR, Acs A, Ludwig C, Panton UH. Economic burden of cardiovascular disease in type 2 diabetes: A systematic review. Value Health. 2018; 21(7): 881-890. doi: 10.1016/j.jval.2017.12.019
33. D’agostino RB, Sullivan L, Parise H, Kannel WB. Overweight and obesity as determinants of cardiovascular risk: The Framingham experience. Arch Intern Med. 2002; 162(16): 1867-1872. doi: 10.1001/archinte.162.16.1867
34. Yang HK, Han K, Kwon H-S, Park Y-M, Cho J-H, Yoon K-H, et al. Obesity, metabolic health, and mortality in adults: A nationwide population-based study in Korea. Sci Rep. 2016; 6: 30329. doi: 10.1038/srep30329
35. Jensen MK, Chiuve SE, Rimm EB, Dethlefsen C, Tjønneland A, Joensen AM, et al. Obesity, behavioral lifestyle factors, and risk of acute coronary events. Circulation. 2008; 117(24): 3062-3069. doi: 10.1161/CIRCULATIONAHA.107.759951
36. Abou-Raya S, Naeem A, Abou-El KH, El BS. Coronary artery disease and periodontal disease: Is there a link? Angiology. 2002; 53(2): 141-148. doi: 10.1177/000331970205300203
37. Noda H, Iso H, Saito I, Konishi M, Inoue M, Tsugane S. The impact of the metabolic syndrome and its components on the incidence of ischemic heart disease and stroke: the Japan public health center-based study. Hypertens Res. 2009; 32(4): 289-298. doi: 10.1038/hr.2009.14
38. Nguyen E, Coleman CI, Kohn CG, Weeda ER. Ranolazine in patients with type 2 diabetes and chronic angina: A cost-effectiveness analysis and assessment of health-related quality-of-life. Int J Cardiol. 2018; 273: 34-38. doi: 10.1016/j.ijcard.2018.09.060
39. Ambrosio G, Tamargo J, Grant PJ. Non-haemodynamic anti-anginal agents in the management of patients with stable coronary artery disease and diabetes: A review of the evidence. Diab Vasc Dis Res. 2016; 13(2): 98-112. doi: 10.1177/1479164115609028
40. Amano A, Inaba H. Cardiovascular diseases and periodontal diseases. Clin Calcium. 2012; 22(1): 43-48.
41. Abou-Raya S, Abou-Raya A, Naim A, Abuelkheir H. Rheumatoid arthritis, periodontal disease and coronary artery disease. Clin Rheumatol. 2008; 27(4): 421-427. doi: 10.1007/s10067-007-0714-y
42. Zhang J, Chen L, Delzell E, Muntner P, Hillegass WB, Safford MM, et al. The association between inflammatory markers, serum lipids and the risk of cardiovascular events in patients with rheumatoid arthritis. Ann Rheum Dis. 2014; 73(7): 1301-1308. doi: 10.1136/annrheumdis-2013-204715
43. Liu P, Zhang Y, Wang SJ, Zhang FH, Zheng PH. Correlation between periodontal disease and coronary atherosclerotic heart disease. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2006; 28(2): 169-172.
44. Lavelle C. Is periodontal disease a risk factor for coronary artery disease (CAD)? J Can Dent Assoc. 2002; 68(3): 176-180.
45. Parameter on systemic conditions affected by periodontal diseases. J Periodontol. 2000; 71(5): 880-883. doi: 10.1902/jop.2000.71.5-S.880
46. Kinane DF, Stathopoulou PG, Papapanou PN. Periodontal diseases. Nat Rev Dis Primers. 2017; 3: 17038. doi: 10.1038/nrdp.2017.38
47. Ramenzoni LL, Lehner MP, Kaufmann ME, Wiedemeier D, Attin T, Schmidlin PR. Oral diagnostic methods for the detection of periodontal disease. Diagnostics (Basel). 2021; 11(3): 571. doi: 10.3390/diagnostics11030571
48. Amano A. Periodontal diseases and systemic diseases. Clin Calcium. 2017; 27(10): 1383-1391.
49. Brown LJ, Brunelle JA, Kingman A. Periodontal status in the United States, 1988–91: Prevalence, extent, and demographic variation. J Dent Res. 1996; 75: 672-683. doi: 10.1177/002203459607502S07
50. Nazir M, Al-Ansari A, Al-Khalifa K, Alhareky M, Gaffar B, Almas K. Global prevalence of periodontal disease and lack of its surveillance. Sci World J. 2020; 2020: 2146160. doi: 10.1155/2020/2146160
51. Eke PI, Wei L, Borgnakke WS, Thornton-Evans G, Zhang XY, Hua L, et al. Periodontitis prevalence in adults ≥ 65 years of age, in the USA. Periodontol 2000. 2016; 72(1): 76-95: doi: 10.1111/prd.12145
52. Douglass CW, Jette AM, Fox CH, Tennstedt SL, Joshi A, Feldman HA, et al. Oral health status of the elderly in New England. J Gerontol. 1993; 48(2): M39-46: doi: 10.1093/geronj/48.2.m39
53. Eke PI, Borgnakke WS, Genco RJ. Recent epidemiologic trends in periodontitis in the USA. Periodontol 2000. 2020; 82(1): 257-267: doi: 10.1111/prd.12323
54. Rutger PG, Thomas I. Periodontitis and cardiovascular disease. Ther Umsch. 2008; 65(2): 121-126. doi: 10.1024/0040-5930.65.2.121
55. Persson GR, Persson RE. Cardiovascular disease and periodontitis: An update on the associations and risk. J Clin Periodontol. 2008; 35(8): 362-379: doi: 10.1111/j.1600-051X.2008.01281.x
56. Foz MA, Romito AG, Bispo MC, Petrillo LC, Patel K, Suvan J, et al. Periodontal therapy and biomarkers related to cardiovascular risk. Minerva Stomatol. 2010; 59(5): 271-283.
57. Nakajima T, Honda T, Domon H, Okui T, Kajita K, Ito H, et al. Periodontitis-associated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease. J Periodontal Res. 2010; 45(1): 116-122: doi: 10.1111/j.1600-0765.2009.01209.x
58. Arbes Jr SJ, Slade GD, Beck JD. Association between extent of periodontal attachment loss and self-reported history of heart attack: An analysis of NHANES III data. J Dent Res. 1999; 78(12): 1777-1782. doi: 10.1177/00220345990780120301
59. Buhlin K, Gustafsson A, Hаkansson J, Klinge B. Oral health and cardiovascular disease in Sweden. J Clin Periodontol. 2002; 29(3): 254-259. doi: 10.1034/j.1600-051x.2002.290312.x
60. Mattila KJ, Valle MS, Nieminen MS, Valtonen VV, Hietaniemi KL. Dental infections and coronary atherosclerosis. Atherosclerosis. 1993; 103(2): 205-211. doi: 10.1016/0021-9150(93)90263-t
61. Ajwani S, Mattila KJ, Tilvis RS, Ainamo A. Periodontal disease and mortality in an aged population. Spec Care Dentist. 2003; 23(4): 125-130. doi: 10.1111/j.1754-4505.2003.tb00297.x
62. Loos BG. Systemic effects of periodontitis. Ann R Australas Coll Dent Surg. 2006; 18: 27-29.
63. Beck JD, Offenbacher S. The association between periodontal diseases and cardiovascular diseases: A state-of-thescience review. Ann Periodontol. 2001; 6(1): 9-15. doi: 10.1902/annals.2001.6.1.9
64. Loesche WJ, Schork A, Terpenning MS, Chen YM, Dominguez BL, Grossman N. Assessing the relationship between dental disease and coronary heart disease in elderly U.S. veterans. J Am Dent Assoc. 1998; 129(3): 301-311. doi: 10.14219/jada.archive.1998.0204
65. Naderi S, Merchant AT. The association between periodontitis and cardiovascular disease: An update. Curr Atheroscler Rep. 2020; 22(10): 52. doi: 10.1007/s11883-020-00878-0
66. Aditi P, Amit KD, Dhrubajyoti B, Veena K, Zaghlol R, Basyal B, et al. Periodontal inflammation and the risk of cardiovascular disease. Curr Atheroscler Rep. 2020; 22(7): 28. doi: 10.1007/s11883-020-00848-6
67. Söder PO, Söder B, Nowak J, Jogestrand T. Early carotid atherosclerosis in subjects with periodontal diseases. Stroke. 2005; 36(6): 1195-1200. doi: 10.1161/01.STR.0000165916.90593.cb
68. Srivastava MC, Srivastava R, Verma PK, Gautam A. Metabolic syndrome and periodontal disease: An overview for physicians. J Family Med Prim Care. 2019; 8(11): 3492-3495. doi: 10.4103/jfmpc.jfmpc_866_19
69. Lamster IB, Pagan M. Periodontal disease and the metabolic syndrome. Int Dent J. 2017; 67(2): 67-77. doi: 10.1111/idj.12264
Review
For citations:
Khaptanova V.A., Golmenko A.D., Khaptanov A.Yu., Gamayunov D.Yu. Relationship of coronary heart disease and comorbide dental background. Acta Biomedica Scientifica. 2021;6(4):87-99. (In Russ.) https://doi.org/10.29413/ABS.2021-6.4.8
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