Overview of potential drugs for the treatment of new coronavirus Infection (COVID-19)
https://doi.org/10.29413/ABS.2021-6.4.7
Abstract
The new coronavirus infection (SARS-CoV-2), better known as COVID-19, quickly evolved into a worldwide pandemic with a significant public health burden. Currently, there are no approved drugs or preventive therapeutic strategies to combat infection. Decisions about prescribing many medications are made based on the results obtained in in vitro studies, or expert opinions. Most of the drugs currently used to treat COVID-19 are approved antivirals or antibodies against other diseases. However, there are hundreds of clinical studies underway around the world to discover effective treatments for COVID-19. This article summarizes the results of clinical studies of potential therapeutic drugs used as COVID-19 therapy. Based on this review, it can be concluded that there is still no high-quality evidence to support any of the drugs described below. Until the unambiguous results of randomized controlled trials are available, the use of any of the following drugs is not clinically proven as an effective treatment for COVID-19.
About the Authors
Ya. E. Shirobokov
Samara State Medical University
Russian Federation
Russian Federation
Postgraduate at the Department of Pharmacy Management and Economics
Chapayevskaya str. 89, Samara 443099, Russian Federation
E. P. Gladunova
Samara State Medical University
Russian Federation
Russian Federation
Dr. Sc. (Pharm.), Docent, Professor at the Department of Pharmacy Management and Economics
Chapayevskaya str. 89, Samara 443099, Russian Federation
E. A. Borodulina
Samara State Medical University
Russian Federation
Russian Federation
Dr. Sc. (Med.), Professor, Head of the Department of Phthisiology and Pulmonology
Chapayevskaya str. 89, Samara 443099, Russian Federation
A. E. Sukhanova
Samara State Medical University
Russian Federation
Russian Federation
Resident at the Department of Phthisiology and Pulmonology
Chapayevskaya str. 89, Samara 443099, Russian Federation
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Review
For citations:
Shirobokov Ya.E., Gladunova E.P., Borodulina E.A., Sukhanova A.E. Overview of potential drugs for the treatment of new coronavirus Infection (COVID-19). Acta Biomedica Scientifica. 2021;6(4):74-86. (In Russ.) https://doi.org/10.29413/ABS.2021-6.4.7
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