Preview

Acta Biomedica Scientifica

Advanced search

Proliferative activity of salivary tumor cells

https://doi.org/10.12737/23393

Abstract

Salivary carcinomas comprise 2-3 % of malignant tumors of the head and neck. The basic method of morphological study in early diagnostics is aspiration puncture with a fine needle (FNAB). Complex histologic structure and great diversity of morphological items complicate cytologic diagnostics of salivary tumors considerably. Immunocytochemical examination must be used to reduce the errors, it enables to reveal neoplastic cells at early stages of malignization. High proliferative activity of tumor cells is one of their biological peculiarities. Accuracy in differential diagnostics between benign and malignant tumors is improved through determination of mitotic index combined with a fine needle aspiration puncture.

About the Authors

D. V. Bychkov
Irkutsk State Medical University
Russian Federation


Y. K. Batoroev
Irkutsk Regional Cancer Center
Russian Federation


I. G. Alyoshkin
Irkutsk State Medical University
Russian Federation


L. Y. Kislitsyna
Irkutsk State Medical University
Russian Federation


V. A. Kazimirsky
Irkutsk State Medical University
Russian Federation


L. Y. Rayevskaya
Irkutsk Diagnostic Center
Russian Federation


S. V. Nemchinova
Irkutsk Regional Cancer Center
Russian Federation


E. V. Filchenkova
Irkutsk State Medical University
Russian Federation


References

1. Майборода А.А. Молекулярно-генетические особенности онкогенеза: пособие для врачей. - Иркутск: ИГМУ 2015. - 54 с

2. Панфилова М.М. Цитологическое исследование в диагностике опухолей и опухолевидных заболеваний в околоушной слюнной железе // Вопр. клин. мед. - Душанбе, 1970. - Вып. 1. - С. 178-179

3. Пачес А.И. Опухоли головы и шеи; 4-е изд. - М.: Медицина, 2000. - 480 с

4. Тарасенко С.В., Смысленова М.В., Шипкова Т.П., Руднев А.И. Дифференциальная диагностика, включающая сравнение морфологических и сонографических особенностей новообразований больших слюнных желез // Российский стоматологический журнал. - 2014. - № 3. - С. 39-41

5. Федяев И.М., Байриков И.М., Белова Л.П., Шувалова Т.В. Злокачественные опухоли челюстно-лицевой области. - М.: Медицинская книга; Н. Новгород: Изд-во НГМА, 2000. - 160 с

6. Alves F.A., Pires F.R., de Almedia O.P. (2004). PCNA, Ki-67 and p53 expressions in submandibular salivary gland tumors. Int. J. Oral-Maxilofac. Surg., 33 (6), 593597.

7. Horii A., Yoshida J., Sakai M. (1998). Flow cytometric analysis of DNA content and Ki-67-positive fractions in diagnosis of salivary gland tumors. Eur. Arch. Otorhinolaryngol., 255 (5), 265-268.


Review

For citations:


Bychkov D.V., Batoroev Y.K., Alyoshkin I.G., Kislitsyna L.Y., Kazimirsky V.A., Rayevskaya L.Y., Nemchinova S.V., Filchenkova E.V. Proliferative activity of salivary tumor cells. Acta Biomedica Scientifica. 2016;1(5):68-70. (In Russ.) https://doi.org/10.12737/23393

Views: 539


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2541-9420 (Print)
ISSN 2587-9596 (Online)