Mexametric Assessment of Melanin Level in Children's Skin
V. A. Shamrikova,
E. D. Sorokina,
E. V. Dubrovskaya,
Y. A. Krakhaleva,
E. A. Kurniavkina,
Y. M. Krinitsyna,
A. I. Yakubovich,
I. G. Sergeeva https://doi.org/10.29413/ABS.2020-5.2.2
Abstract
Background. High predisposition to sunburn in childhood and associated increased risk of malignant skin tumors development, decrease with age. There is a likelihood of a relationship between the described trends and dynamic age related changes in functional state of melanocytes and melanin.
Aim: to evaluate the level of melanin in the skin in children of different age. Materials and methods. The study involved 78 children aged from 7 to 17 years, without any disorders of skin pigmentation. Three groups of observations were formed: Group 1 - 28 children from 7 to 9 years, Group 2 - 25 children from 10 to 12 years, Group 3 - 25 children from 16 to 17years. The melanin level was evaluated in the skin of face, body and extremities using mexametry.
Results. The highest level of skin melanin was observed in forearms and lower legs in all age groups (up to 28.3 ± 10.8, 23.3 ± 8.6 and 26.7 ± 10.6 c.u. in Group 1, 2 and 3 respectively), the lowest - in cheeks and chest (up to 8.0 ± 4.7, 4.4 ± 3.4 and 9.5 ± 4.1 c.u. in Group 1, 2 and 3 respectively). There were relationships between skin site and level of melanin, but no relationships between level of melanin and gender or age.
Findings. The level of melanin in the skin in children aged from 7 to 17 years is individual and depends on the location of the skin area, but does not depend on gender or age. The distribution of melanin in the skin is stable and does not change over time.
About the Authors
V. A. Shamrikova
Novosibirsk State University
Russian Federation
Russian Federation
Valentina A. Shamrikova - Student, Novosibirsk State University.
Pirogova str. 2, Novosibirsk 630090.
E. D. Sorokina
Novosibirsk State University
Russian Federation
Russian Federation
Elena D. Sorokina - Clinical Resident, Novosibirsk State University.
Pirogova str. 2, Novosibirsk 630090.
E. V. Dubrovskaya
Lyceum N 9
Russian Federation
Russian Federation
Elina V. Dubrovskaya - Student, Municipal Autonomous Educational Institution “Lyceum N 9”.
1905 year str. 41, Novosibirsk 632901.
Y. A. Krakhaleva
Novosibirsk State University
Russian Federation
Russian Federation
Yulia A. Krakhaleva - Clinical Resident, Novosibirsk State University.
Pirogova str. 2, Novosibirsk 630090.
E. A. Kurniavkina
Sanatorium Krasnozersky
Russian Federation
Russian Federation
Elena A. Kurniavkina - Cand. Sc. (Med), Head Physician, Sanatorium “Krasnozersky”.
Sanatorium str. 1, Kaigorodsky village, Krasnozersky district 632901, Novosibirsk Region.
Y. M. Krinitsyna
Novosibirsk State University; Federal Research Center of Fundamental and Translational Medicine
Russian Federation
Russian Federation
Yulia M. Krinitsyna - Dr. Sc. (Med), Professor of the Department of Fundamental Medicine at the Zelman Institute of Medicine and Psychology, Novosibirsk State University; Senior Research Officer, Federal Research Center of Fundamental and Translational Medicine.
Pirogova str. 2, Novosibirsk 630090; Timakova str. 2, Novosibirsk 630117, Novosibirsk Region.
A. I. Yakubovich
Irkutsk State Medical University
Russian Federation
Russian Federation
Andrey I. Yakubovich - Dr. Sc. (Med), Professor, Head of the Department of Dermatovenerology and Cosmetology, Irkutsk State Medical University.
Krasnogo Vosstania str. 1, Irkutsk 664003.
I. G. Sergeeva
Novosibirsk State University
Russian Federation
Russian Federation
Irina G. Sergeeva - Dr. Sc. (Med), Professor of the Department of Fundamental Medicine at the Zelman Institute of Medicine and Psychology, Director of the Center for Postgraduate Medical Education, Novosibirsk National Research State University.
Pirogova str. 2, Novosibirsk 630090.
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Review
For citations:
Shamrikova V.A., Sorokina E.D., Dubrovskaya E.V., Krakhaleva Y.A., Kurniavkina E.A., Krinitsyna Y.M., Yakubovich A.I., Sergeeva I.G. Mexametric Assessment of Melanin Level in Children's Skin. Acta Biomedica Scientifica. 2020;5(2):12-16. (In Russ.) https://doi.org/10.29413/ABS.2020-5.2.2
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