actabiomedicaActa Biomedica ScientificaActa Biomedica Scientifica2541-94202587-9596Scientific Centre for Family Health and Human Reproduction Problemsactabiomedica-919Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEСОДЕРЖАНИЕ РЕГУЛЯТОРНЫХ Т-КЛЕТОК В ПЕРИФЕРИЧЕСКОЙ КРОВИ И ЭНДОМЕТРИАЛЬНОЙ ТКАНИ В ДИНАМИКЕ МЕНСТРУАЛЬНОГО ЦИКЛАCONTENTS OF REGULATORY T-CELLS IN PERIPHERAL BLOOD AND ENDOMETRIAL TISSUE IN DYNAMIC OF MENSTRUAL CYCLEХонинаН. А.KhoninaN. A.nkhonina@mail.ruСеледцоваН. В.SeledtsovaN. V.noemail@neicon.ruТихоноваМ. А.TikhonovaM. A.noemail@neicon.ruОвсянниковаТ. В.OvsyannikovaT. V.noemail@neicon.ruЧерныхЕ. Р.ChernykhE. R.bmt-novosibirsk@mail.ruНИИ клинической иммунологии СО РАМНРоссияResearch Institute of Clinical Immunology SB RAMSRussian FederationЦентр новых медицинских технологий Института химической биологии и фундаментальной медицины СО РАНРоссияCenter of New Medical Technologies of Institute of Chemical Biology and Fundamental Medicine SB RAMSRussian Federation20122805201203(2)208211Copyright © Хонина Н.А., Селедцова Н.В., Тихонова М.А., Овсянникова Т.В., Черных Е.Р., 20122012Хонина Н.А., Селедцова Н.В., Тихонова М.А., Овсянникова Т.В., Черных Е.Р.Khonina N.A., Seledtsova N.V., Tikhonova M.A., Ovsyannikova T.V., Chernykh E.R.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.actabiomedica.ru/jour/article/view/919

В работе исследовано содержание CD4+CD25+/high и CD4+CD25+CD127- регуляторных Т-клеток в периферической, менструальной крови, и эндометриальной ткани в разные фазы менструального цикла. Показано, что в фазу средней секреции регистрируется увеличение числа регуляторных Т-клеток, при этом в периферической циркуляции возрастает количество CD4+CD25+/high клеток, а в эндометриальной ткани нарастает число CD4+CD25+CDl27- клеток.

The maintenance of CD4+CD25+/high and CD4+CD25+CD127 — regulatory T-cells in a peripheral, menstrual blood and an endometrial tissue in different phases of a menstrual cycle is investigated. It is shown that in a phase of average secretion the number of regulatory T-cells is increased. Thus quantity of CD4+CD25+increased in peripheral circulation, and in an endometrial tissue number of CD4+CD25+CD127- cells grew.

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The authors declare that there are no conflicts of interest present.