actabiomedicaActa Biomedica ScientificaActa Biomedica Scientifica2541-94202587-9596Scientific Centre for Family Health and Human Reproduction Problemsactabiomedica-7Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEУльтразвуковая диагностика ассоциированного с диализом амилоидозаUltrasound diagnostics of the dialysis-related amyloidosisПолухинаЕ. В.PolukhinaE. V.polukhina@inbox.ruКГБОУ ДПО «Институт повышения квалификации специалистов здравоохранения» МинздраваРоссияPostgraduate Institute For Public Health WorkersRussian Federation201528022015013438Copyright © Полухина Е.В., 20152015Полухина Е.В.Polukhina E.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.actabiomedica.ru/jour/article/view/7

Проведена оценка возможностей ультразвукового метода в диагностике ассоциированного с диализом амилоидоза (АДА) у пациентов на диализе. Проанализированы взаимосвязь наличия АДА и особенности изменения ультразвуковой картины суставов. Отмечено более частое вовлечение в патологических процесс плечевых (92,9%) и тазобедренных суставов (64,3%). Приведенные данные указывают на высокую информативность данныхультразвукового исследования в выявлении АДА, что позволяет во многих случаях обойтись без других методов визуализации.

Dialysis-related amyloidosis (DRA) is a serious complication arising in the context of long-term hemodialysis or continuous ambulatory peritoneal dialysis. DRA predominantly involves the osteoarticular system and is clinically manifested by erosive and destructive osteoarthropathies and carpal tunnel syndrome. The aim of this study was to establish distinguishing features of the DRA in dialysis patients by using ultrasound. Joints and soft tissues of 200 patients with chronic kidney disease receiving dialysis were studied by ultrasound. Fourteen patients (7,0%) had clinically and radiologically evident, biopsy proven DRA. In this group of patients, all patients were receiving hemodialysisfor an average of 168 months. There was positive correlation found between dialysis duration and presence of DRA (Rs = 0,667; p < 0,001). The relationship between presence of DRA and discovered joints changes using ultrasound is analyzed. More frequent involvement in the pathological process shoulder (92,9%) and hip joints (64,3%) was noted. There were statistically significant differences in rotator cuff thickness and hip joint anterior synovial space thickness in patients with DRA compare to general group (p < 0,001). Ultrasound is a highly informative method of diagnosing DRA in patients with end-stage renal disease. It provides detailed soft tissue and joint description substituting other imaging modalities.

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The authors declare that there are no conflicts of interest present.