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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2026-11.4.19</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-6334</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SURGERY</subject></subj-group></article-categories><title-group><article-title>Прогностические параметры, влияющие на эффективность удаления доброкачественных эпителиальных новообразований типа LST толстой и прямой кишки</article-title><trans-title-group xml:lang="en"><trans-title>Prognostic parameters affecting the effectiveness of removing benign epithelial neoplasms of the LST type in the colon and rectum</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5653-2960</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Архипова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Arkhipova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Архипова Анна Александровна – доктор медицинских наук, заведующая консультативно-диагностическим отделением клиника на Ленинском проспекте</p><p>119071, г. Москва, Ленинский проспект, 20, строение 1</p></bio><bio xml:lang="en"><p>Anna A. Arkhipova – Dr. Sc. (Med.), Head of the Consultative and Diagnostic Department of the Medsi Clinic on Leninsky Prospekt</p><p>Leninsky Prospekt, 20, Building 1, Moscow 119071</p></bio><email xlink:type="simple">ierusalimova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1178-5205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анищенко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Anishchenko</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анищенко Владимир Владимирович – доктор медицинских наук, профессор, заведующий кафедрой хирургии факультета усовершенствования врачей ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России; врач-хирург Клинического госпиталя «АВИЦЕННА» Группы компаний «Мать и дитя»</p><p>630091, г. Новосибирск, Красный проспект, 52, </p><p>630099, г. Новосибирск, ул. Коммунистическая, д. 17</p></bio><bio xml:lang="en"><p>Vladimir V. Anishchenko – Dr. Sc. (Med.), professor, head of the Department of Surgery, Faculty of Postgraduate Medical Education, Novosibirsk State Medical University of the Ministry of Health of the Russian Federation; surgeon, “AVICENNA” Clinical Hospital of the Mother and Child Group of Companies</p><p>Krasny Prospekt, 52, Novosibirsk 630091,</p><p>Kommunisticheskaya St., 17, Novosibirsk 630099</p></bio><email xlink:type="simple">AVV1110@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-0017-9402</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абакарова</surname><given-names>Д. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Abakarova</surname><given-names>D. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Абакарова Диана Хабибовна – врач-эндоскопист консультативно-диагностического отделения клиники на Ленинском проспекте </p><p>119071, г. Москва, Ленинский проспект, 20, строение 1</p></bio><bio xml:lang="en"><p>Diana Kh. Abakarova – endoscopist of the Consultative and diagnostic department, Medsi Clinic on Leninsky Prospekt </p><p>Leninsky Prospekt, 20, Building 1, Moscow 119071</p></bio><email xlink:type="simple">ierusalimova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>АО «ГК «Медси»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>JSC «Medsi Group of Companies»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России;&#13;
Клинический госпиталь «АВИЦЕННА»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University of the Ministry of Health of the Russian Federation;&#13;
AVICENNA Clinical Hospital, Mother and Child Group of Companies</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>17</day><month>10</month><year>2026</year></pub-date><volume>11</volume><issue>4</issue><fpage>190</fpage><lpage>196</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Архипова А.А., Анищенко В.В., Абакарова Д.Х., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Архипова А.А., Анищенко В.В., Абакарова Д.Х.</copyright-holder><copyright-holder xml:lang="en">Arkhipova A.A., Anishchenko V.V., Abakarova D.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/6334">https://www.actabiomedica.ru/jour/article/view/6334</self-uri><abstract><sec><title>Обоснование</title><p>Обоснование. Непреложным фактом является связь полипов толстой кишки с колоректальным раком. Соответственно главной мерой предупреждения колоректального рака является удаление эпителиальных новообразований, а эффективность резекции зависит от разных факторов.</p></sec><sec><title>Цель</title><p>Цель. Определить, влияет ли размер, локализация, макроскопический тип, морфологический характер, способ резекции на эффективность удаления стелющихся эпителиальных новообразований толстой и прямой кишки.</p></sec><sec><title>Методы</title><p>Методы. Проведен ретроспективный анализ случаев удаления эпителиальных новообразований типа LST толстой и прямой кишки за 2023 год. У 165 пациентов с доброкачественными эпителиальными новообразованиями размерами 11–30 мм (средний размер составил 15 ± 4,43 мм) была проведена эндоскопическая резекция. Восьми пациентам с гигантскими эпителиальными новообразованиями размером 6–14 см в длину – до 2\3 окружности просвета прямой кишки выполнена SILS-трансанальная резекция. Пациентов приглашали через 3, 6 и 12 месяцев на контрольный осмотр после удаления.</p></sec><sec><title>Результаты</title><p>Результаты. Выявлена связь возникновения рецидива эпителиального новообразования типа LST с размером (от 20 до 30 мм, p = 0.010), макроскопическим типом (гранулярный, смешанный, узловой, p = 0,012) и морфологическим характером (тубулярно-ворсинчатая аденома, p = 0,028). При удалении эпителиального образования во всех случаях края раны на слизистой скрупулезно осматривались на предмет остаточной ткани, при обнаружении резидуальная ткань удалялась полностью. Мы предполагаем, что клетки тубулярно-ворсинчатой аденомы могли быть имплантированы инъектором или петлей в подслизистый слой во время удаления образования. В группе SILS-TAR рецидивов не было. Однако SILS-port (COVIDIEN) с недавнего времени снят с производства.</p></sec><sec><title>Заключение</title><p>Заключение. Вопрос возможности имплантации клеток доброкачественной аденомы инъектором или петлей в подслизистый слой во время резекции требует дальнейшего изучения. Также необходимо продолжить поиск, разработку новых недорогих и эффективных методик удаления гигантских ворсинчатых аденом прямой кишки.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. It is an undeniable fact that colon polyps are associated with colorectal cancer. The main measure for preventing colorectal cancer is the removal of epithelial neoplasms. However, the effectiveness of resection depends on various factors.</p></sec><sec><title>Aim</title><p>Aim. To determine whether the size, location, macroscopic type, morphology, and the method of resection influence the effectiveness of removal of laterally spreading tumors in the colon and rectum.</p></sec><sec><title>Methods</title><p>Methods. We conducted a retrospective analysis of cases of removal of LST type epithelial neoplasms in the colon and rectum in 2023. Endoscopic resection was performed in 165 patients with benign epithelial neoplasms ranging in size from 11 to 30 mm, with an average size of 15 ± 4.43 mm. Eight patients with giant epithelial neoplasms measuring 6–14 cm in length, up to 2/3 of the circumference of the rectal lumen, underwent SILS-transanal resection. Patients were invited for follow-up examination at 3, 6 and 12 months after removal.</p></sec><sec><title>Results</title><p>Results. We found a relationship between the relapse of the LST type epithelial neoplasm and the size (from 20 to 30 mm, p = 0.010), macroscopic type (granular mixed-nodular, p = 0.012) and morphology (tubulovillous adenoma, p = 0.028) of the previously resected lesion. In all cases, when removing the epithelial lesion, the edges of the wound on the mucosa were carefully examined for residual tissue. If found, the residual tissue was removed completely. We suggest that tubulovillous adenoma cells might have been implanted into the submucosa with an injector or a snare during removal of the lesion. The SILS-TAR group showed no relapses. However, the SILS-port (COVIDIEN) was recently discontinued.</p></sec><sec><title>Conclusion</title><p>Conclusion. The possibility of accidental implantation of benign adenoma cells into the submucosa with an injector or a snare during resection warrants further study. It is also necessary to continue the search for and development of new affordable and effective methods for removing giant villous adenomas of the rectum.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>эпителиальные новообразования</kwd><kwd>эндоскопическая резекция</kwd><kwd>SILS-трансанальная резекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epithelial neoplasms</kwd><kwd>endoscopic resection</kwd><kwd>SILS-transanal resection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Состояние онкологической помощи населению России в 2024 году / под ред. Каприна А.Д., Старинского В.В., Шахзадовой А.О. 2025; 275.</mixed-citation><mixed-citation xml:lang="en">The state of oncological care for the population of Russia in 2024 / edited by A.D. Kaprin, V.V. Starinsky, A.O. Shakhzadova. 2025; 275. 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