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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.12737/article_59a614f8afcde0.78457348</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-615</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>НЕПОЛНАЯ КОРОНАРНАЯ РЕВАСКУЛЯРИЗАЦИЯ КАК НЕЗАВИСИМЫЙ ФАКТОР РИСКА УХУДШЕНИЯ ПРОГНОЗА КОРОНАРНОГО ШУНТИРОВАНИЯ БЕЗ ИСКУССТВЕННОГО КРОВООБРАЩЕНИЯ У БОЛЬНЫХ ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА</article-title><trans-title-group xml:lang="en"><trans-title>INCOMPLETE CORONARY REVASCULARIZATION AS AN INDEPENDENT RISK FACTOR OF OFF-PUMP CORONARY ARTERY BYPASS GRAFTING PROGNOSIS IN PATIENTS WITH ISCHEMIC HEART DISEASE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подкаменный</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Podkamenniy</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">pvdm@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лиханди</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Likhandi</surname><given-names>D. I.</given-names></name></name-alternatives><email xlink:type="simple">likhandi_di@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Желтовский</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zheltovsky</surname><given-names>Y. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаравин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharavin</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вырупаев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vyrupaev</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Иркутская государственная медицинская академия последипломного образования -филиал ФГБОУ «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ГБУЗ «Иркутская ордена «Знак почёта» областная клиническая больница»</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Russian Medical Academy of Continuing Professional Education; Irkutsk Regional Clinical Hospital</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ «Иркутская ордена «Знак почёта» областная клиническая больница»</institution></aff><aff xml:lang="en"><institution>Irkutsk Regional Clinical Hospital</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Иркутская государственная медицинская академия последипломного образования -филиал ФГБОУ «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России; ГБУЗ «Иркутская ордена «Знак почёта» областная клиническая больница»</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Russian Medical Academy of Continuing Professional Education; Irkutsk State Medical University; Irkutsk Regional Clinical Hospital</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2017</year></pub-date><volume>2</volume><issue>2</issue><fpage>40</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Подкаменный В.А., Лиханди Д.И., Желтовский Ю.В., Шаравин А.А., Вырупаев А.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Подкаменный В.А., Лиханди Д.И., Желтовский Ю.В., Шаравин А.А., Вырупаев А.В.</copyright-holder><copyright-holder xml:lang="en">Podkamenniy V.A., Likhandi D.I., Zheltovsky Y.V., Sharavin A.A., Vyrupaev A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/615">https://www.actabiomedica.ru/jour/article/view/615</self-uri><abstract><p>Обследованы 1418 больных ишемической болезнью сердца, оперированных в период с 2001 по 2014 гг. Из них у 469 была выполнена неполная коронарная реваскуляризация (НКР), у остальных (n = 949) - полная коронарная реваскуляризация (ПКР). В ходе сравнительной оценки отдалённые результаты операций с ПКР и НКР оценивались по количеству и времени наступления больших кардиальных событий и выживаемости. Выживаемость и свобода от больших кардиальных событий были статистически значимо выше у больных после ПКР, т. е. доказана роль НКР как независимого фактора риска ухудшения отдалённых результатов коронарного шунтирования.</p></abstract><trans-abstract xml:lang="en"><p>Currently, most researchers define the term complete coronary revascularization (CCR) as coronary arterial bypass graft (CABG) of at least one branch of each of the three affected coronary basins: left anterior descending artery (LAD) left circumflex artery (LCA) and right coronary artery RCA. The rejection of bypass of one or more diseased coronary basin is estimated as an incomplete coronary revascularization (ICR). Material and methods. This retrospective study included patients, underwent isolated coronary bypass operations from 2001 to 2014 in the Irkutsk Regional Hospital. 1418 patients underwent isolated off-pump bypass operations. ICR occurred in 469 patients, the CCR - in 949. All patients were divided into 2 groups: ICR group and CCR group. These groups were compared by the late survival and by the frequency of the major cardiac events (MACE). The results of study were assessed after 1, 5 and 10 years from the date of CABG. Results. Survival of patients of ICR group after 1,5,10 years after surgery was 98.5 %, 75.4 % and 75.4 % respectively, of CCR group of patients - 98.7 %, 88.7 % and 81.3 % (p = 0.006). In ICR group "free" from MACE after 1, 5 and 10 years after surgery were respectively 98.2 %, 70.8 % and 61.0 % of patients, while in CCR group those made 98.3 %, 84.6 % and 72,6 % (p = 0,007). We can conclude that incomplete revascularization can be defined as a prediction factor of worst long-term outcome results of CABG.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>коронарное шунтирование</kwd><kwd>отдалённые результаты</kwd><kwd>неполная коронарная реваскуляризация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coronary artery bypass surgery</kwd><kwd>remote outcomeы</kwd><kwd>incomplete coronary revascularization</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bell M.R., Gersh B.J., Shaff H.V., Holmes D.R., Fisher L.D., Alderman E.L., Myers W.O., Parsons L.S., Reeder G.S. (1992). Effect of completeness of revascularization on long-term outcome of patients with three-vessel disease undergoing coronary artery bypass grafting: A report from CASS registry. Circulation, 86, 446-457.</mixed-citation><mixed-citation xml:lang="en">Bell M.R., Gersh B.J., Shaff H.V., Holmes D.R., Fisher L.D., Alderman E.L., Myers W.O., Parsons L.S., Reeder G.S. (1992). Effect of completeness of revascularization on long-term outcome of patients with three-vessel disease undergoing coronary artery bypass grafting: A report from CASS registry. Circulation, 86, 446-457.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Girerd N., Magne J., Rabilloud M., Charbonneau E., Mohamadi S., Pibarot P., Voisine P., Baillot R., Doyle D., Dumont E., Dagenais F., Mathieu P. (2012). The impact of complete revascularization on long-term survival is strongly dependent on age. Ann. Thorac. Surg., 94, 11661172.</mixed-citation><mixed-citation xml:lang="en">Girerd N., Magne J., Rabilloud M., Charbonneau E., Mohamadi S., Pibarot P., Voisine P., Baillot R., Doyle D., Dumont E., Dagenais F., Mathieu P. (2012). The impact of complete revascularization on long-term survival is strongly dependent on age. Ann. Thorac. Surg., 94, 11661172.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Head S.J., Mack M.J., Holmes D.R. Jr., Piroze M.D., Serruys P.W., Redwood S.R., Colombo A., Morice M., Feldman T.E., Stähle E., Underwood P., Dawkins K.D., Kappetein A.P., Mohr F.W. (2012). Incidence, predictors and outcomes of incomplete revascularization after percutaneous coronary intervention and coronary artery bypass grafting: a subgroup analysis of 3-year SYNTAX data. Eur. J. Cardiothorac. Surg., 41, 535-541.</mixed-citation><mixed-citation xml:lang="en">Head S.J., Mack M.J., Holmes D.R. Jr., Piroze M.D., Serruys P.W., Redwood S.R., Colombo A., Morice M., Feldman T.E., Stähle E., Underwood P., Dawkins K.D., Kappetein A.P., Mohr F.W. (2012). Incidence, predictors and outcomes of incomplete revascularization after percutaneous coronary intervention and coronary artery bypass grafting: a subgroup analysis of 3-year SYNTAX data. Eur. J. Cardiothorac. Surg., 41, 535-541.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kozower B.D., Moon M.R., Barner H.B., Moazami N., Lawton J.S., Pasque M.K., Damiano R.J. Jr. (2005). Impact of complete revascularization on long-term survival after coronary artery bypass grafting in octogenarians. Ann. Thorac. Surg., 80, 112-117.</mixed-citation><mixed-citation xml:lang="en">Kozower B.D., Moon M.R., Barner H.B., Moazami N., Lawton J.S., Pasque M.K., Damiano R.J. Jr. (2005). Impact of complete revascularization on long-term survival after coronary artery bypass grafting in octogenarians. Ann. Thorac. Surg., 80, 112-117.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Mocanu V., Buth K.J., Kelly R., Légaré J.F. (2014). Incomplete revascularization after coronary artery bypass graft operations is independently associated with worse long-term survival. Ann Thorac. Surg., 92, 549-555.</mixed-citation><mixed-citation xml:lang="en">Mocanu V., Buth K.J., Kelly R., Légaré J.F. (2014). Incomplete revascularization after coronary artery bypass graft operations is independently associated with worse long-term survival. Ann Thorac. Surg., 92, 549-555.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Osswald B.R., Blackstone E.H., Tochtermann U., Schweiger P., Thomas G. (2001). Does the completeness of revascularization affect early survival after coronary artery bypass grafting in elderly patients? Eur. J. Cardiothorac. Surg., 20, 120-126.</mixed-citation><mixed-citation xml:lang="en">Osswald B.R., Blackstone E.H., Tochtermann U., Schweiger P., Thomas G. (2001). Does the completeness of revascularization affect early survival after coronary artery bypass grafting in elderly patients? Eur. J. Cardiothorac. Surg., 20, 120-126.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Rastan A.J., Walther T., Falk V., Kempfert J., Merk D., Lehmann S., Holzhey D., Mohr F.W. (2009). Does reasonable incomplete surgical revascularization affect early or long term survival in patients with multivessel coronary artery disease receiving left internal mammary artery bypass to left anterior descending artery? Circulation, 120, 70-77.</mixed-citation><mixed-citation xml:lang="en">Rastan A.J., Walther T., Falk V., Kempfert J., Merk D., Lehmann S., Holzhey D., Mohr F.W. (2009). Does reasonable incomplete surgical revascularization affect early or long term survival in patients with multivessel coronary artery disease receiving left internal mammary artery bypass to left anterior descending artery? Circulation, 120, 70-77.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Scott R., Blackstone E.H., McCarthy P.M., Lytle B.W., Loop F.D., White J.A., Cosgrove D.M. (2000). Isolated bypass grafting of the left internal thoracic artery to the left anterior descending coronary artery: Late consequences of incomplete revascularization. J. Thorac. Cardiovasc. Surg., 120, 173-184.</mixed-citation><mixed-citation xml:lang="en">Scott R., Blackstone E.H., McCarthy P.M., Lytle B.W., Loop F.D., White J.A., Cosgrove D.M. (2000). Isolated bypass grafting of the left internal thoracic artery to the left anterior descending coronary artery: Late consequences of incomplete revascularization. J. Thorac. Cardiovasc. Surg., 120, 173-184.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Sergeant P., Blackstone E.H., Meyns B. (1997). Validation and interdependence with patientvariables of the influence of procedural variables on early and late phase after CAGB. Eur. J. Cardiothorac. Surg., 12, 1-9.</mixed-citation><mixed-citation xml:lang="en">Sergeant P., Blackstone E.H., Meyns B. (1997). Validation and interdependence with patientvariables of the influence of procedural variables on early and late phase after CAGB. Eur. J. Cardiothorac. Surg., 12, 1-9.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Synnergren M.J., Ekroth R., Odén A., Rexius H., Wiklund L. (2008). Incomplete revascularization reduces survival benefit of coronary artery bypass grafting: Role of off-pump surgery. J. Thorac. Cardiovasc. Surg., 136, 29-36.</mixed-citation><mixed-citation xml:lang="en">Synnergren M.J., Ekroth R., Odén A., Rexius H., Wiklund L. (2008). Incomplete revascularization reduces survival benefit of coronary artery bypass grafting: Role of off-pump surgery. J. Thorac. Cardiovasc. Surg., 136, 29-36.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
