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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2026-11.2.15</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-6070</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОФТАЛЬМОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPHTHALMOLOGY</subject></subj-group></article-categories><title-group><article-title>Клинический случай хронического эндофтальмита после факоэмульсификации катаракты: от диагностики к лечению</article-title><trans-title-group xml:lang="en"><trans-title>Chronic postoperative endophthalmitis after phacoemulsification: a case-based review of diagnosis and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8645-7930</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Архипов</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Arkhipov</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Архипов Егор Владимирович – врач-офтальмолог офтальмологического отделения витреоретинальной хирургии.</p><p>664017, Иркутск, ул. Лермонтова, 337</p></bio><bio xml:lang="en"><p>Egor V. Arkhipov – ophthalmologist, vitreoretinal ophthalmology department, Irkutsk branch of the S.N. Fyodorov “Eye microsurgery” Federal State Institution, Ministry of Health of the Russian Federation.</p><p>Lermontov str., 337, Irkutsk 664017</p></bio><email xlink:type="simple">nauka.mntk.irkutsk@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1590-7743</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьмин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzmin</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузьмин Сергей Владимирович – врач-офтальмолог, заведующий операционным блоком.</p><p>664017, Иркутск, ул. Лермонтова, 337</p></bio><bio xml:lang="en"><p>Sergey V. Kuzmin – ophthalmologist, head of the surgical unit, Irkutsk branch of the S.N. Fyodorov “Eye microsurgery” Federal State Institution, Ministry of Health of the Russian Federation.</p><p>Lermontov str., 337, Irkutsk 664017</p></bio><email xlink:type="simple">skz9093@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9100-1751</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайка</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaika</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зайка Владимир Александрович – кандидат медицинских наук, врач-офтальмолог, заместитель директора по организационно-методической работе.</p><p>664017, Иркутск, ул. Лермонтова, 337</p></bio><bio xml:lang="en"><p>Vladimir A. Zaika – Cand. Sc. (Med.), ophthalmologist, Deputy Director for Organizational and Methodological Work, Irkutsk branch of the S.N. Fyodorov “Eye microsurgery” Federal State Institution, Ministry of Health of the Russian Federation, Ministry of Health of the Russian Federation.</p><p>Lermontov str., 337, Irkutsk 664017</p></bio><email xlink:type="simple">vaz.baikal@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3139-2409</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Розанова</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Rozanova</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Розанова Ольга Ивановна – доктор медицинских наук, врач-офтальмолог, заведующая научно-образовательным отделом Иркутского филиала ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова» Минздрава России; ассистент кафедры офтальмологии, ИГМАПО ― филиал ФГБОУ ДПО «РМАНПО».</p><p>664017, Иркутск, ул. Лермонтова, 337; 664049, Иркутск, м/н Юбилейный,100</p></bio><bio xml:lang="en"><p>Olga I. Rozanova – Dr. Sc. (Med.), ophthalmologist, Head of the Scientific and Educational Department, Irkutsk branch of the S.N. Fyodorov “Eye microsurgery” Federal State Institution, Ministry of Health of the Russian Federation, Ministry of Health of the Russian Federation; associate professor of the ophthalmology department, Irkutsk state medical academy of postgraduate education – branch of the Russian Medical Academy of Postgraduate Education of the Ministry of Health of the Russian Federation.</p><p>Lermontov str., 337, Irkutsk 664017; Yubileyny mkr., 100, Irkutsk 664049</p></bio><email xlink:type="simple">olgrozanova@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Иркутский филиал ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова» Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk Branch of S. Fyodorov “Eye Microsurgery” Federal State Institution of the Ministry of Health of the Russian Federation</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Иркутский филиал ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова» Минздрава России; Иркутская государственная медицинская академия последипломного образования ― филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»</institution></aff><aff xml:lang="en"><institution>Irkutsk Branch of S. Fyodorov “Eye Microsurgery” Federal State Institution of the Ministry of Health of the Russian Federation; Irkutsk State Medical Academy of Postgraduate Education – branch of the Russian Medical Academy of Postgraduate Education of the Ministry of Health of the Russian Federation</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>27</day><month>05</month><year>2026</year></pub-date><volume>11</volume><issue>2</issue><fpage>150</fpage><lpage>159</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Архипов Е.В., Кузьмин С.В., Зайка В.А., Розанова О.И., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Архипов Е.В., Кузьмин С.В., Зайка В.А., Розанова О.И.</copyright-holder><copyright-holder xml:lang="en">Arkhipov E.V., Kuzmin S.V., Zaika V.A., Rozanova O.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/6070">https://www.actabiomedica.ru/jour/article/view/6070</self-uri><abstract><p>Хронический послеоперационный эндофтальмит — редкое, инфекционное осложнение после хирургии катаракты, развивающееся спустя 6 недель или более. Консервативная терапия и даже витрэктомия с сохранением ИОЛ могут дать лишь временный эффект, так как комплекс «ИОЛ–капсульный мешок» может оставаться резервуаром инфекции.</p><sec><title>Цель исследования</title><p>Цель исследования. Продемонстрировать опыт хирургического и медикаментозного лечения рецидивирующего хронического послеоперационного эндофтальмита.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Представлен клинический случай пациента с манифестацией хронического послеоперационного эндофтальмита (ХПЭ) через месяц после факоэмульсификации катаракты с имплантацией ИОЛ. Несмотря на консервативную терапию, ремиссии достичь не удавалось. Лечение было комплексным и включало поэтапное выполнение трёх хирургических вмешательств: субтотальная витрэктомия с интравитреальным введением антибиотиков; ревизия витреальной полости с удалением комплекса «ИОЛ–капсульный мешок»; повторное интравитреальное введение антибиотиков и тампонада силиконовым маслом (выполнено при рецидиве воспаления); удаление силиконового масла с последующей имплантацией трёхчастной ИОЛ методом интрасклеральной фиксации по Ямане (выполнено через 6 месяцев после предыдущего вмешательства на фоне полного купирования воспалительного процесса).</p></sec><sec><title>Результаты</title><p>Результаты. После первого этапа лечения острота зрения составила 0,4 н.к. Была достигнута кратковременная ремиссия воспалительного процесса продолжительностью четыре недели. Развившееся обострение послужило показанием ко второму этапу хирургического вмешательства. Удаление комплекса «ИОЛ–капсульный мешок» в сочетании с тампонадой витреальной полости силиконовым маслом привело к стойкому купированию воспаления. В дальнейшем коррекция афакии была выполнена одновременно с аспирацией силикона. За два года послеоперационного наблюдения острота зрения составила 0,8 н.к., рецидивов воспалительного процесса не отмечалось.</p></sec><sec><title>Заключение</title><p>Заключение. При рецидивирующем хроническом послеоперационном эндофтальмите наиболее эффективной тактикой является проведение витрэктомии с удалением комплекса «ИОЛ–капсульный мешок». Вторичная имплантация заднекамерной ИОЛ с интрасклеральной фиксацией по методу Ямане является эффективным способом коррекции афакии.</p></sec></abstract><trans-abstract xml:lang="en"><p>Chronic postoperative endophthalmitis is a rare infectious complication following cataract surgery and develops 6 weeks or more later. Conservative therapy and even vitrectomy with intraocular lens (IOL) retention may provide only a temporary effect, because the “IOL–capsular bag” complex can remain a reservoir of infection.</p><sec><title>The aim</title><p>The aim. To demonstrate the surgical and medical treatment experience of recurrent chronic postoperative endophthalmitis.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods. We report a clinical case of chronic postoperative endophthalmitis that manifested one month after cataract phacoemulsification with IOL implantation. Despite conservative therapy, sustained remission could not be achieved. Management was comprehensive and included three staged surgical procedures: subtotal pars plana vitrectomy with intravitreal antibiotic injection; revision of the vitreous cavity with removal of the “IOL–capsular bag” complex, repeated intravitreal antibiotics, and silicone oil tamponade (performed after recurrence of inflammation); and silicone oil removal followed by implantation of a three-piece IOL using the Yamane sutureless intrascleral fixation technique (performed 6 months after the previous procedure once inflammation had completely resolved).</p></sec><sec><title>Results</title><p>Results. Following the first stage of treatment, uncorrected visual acuity (UCVA) was 0.4. A short-term remission of the inflammatory process lasting four weeks was achieved. A subsequent exacerbation served as an indication for the second stage of surgical intervention. Removal of the IOL-capsular bag complex combined with silicone oil tamponade of the vitreous cavity led to a sustained resolution of inflammation. Subsequently, aphakia correction was performed simultaneously with silicone oil removal. Over the two-year postoperative follow-up period, UCVA reached 0.8, with no recurrence of inflammation.</p></sec><sec><title>Conclusion</title><p>Conclusion. In recurrent chronic postoperative endophthalmitis, the most effective strategy is pars plana vitrectomy with removal of the “IOL–capsular bag” complex. Secondary posterior chamber IOL implantation using the Yamane sutureless intrascleral fixation technique is an effective method for aphakia correction in this setting.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический эндофтальмит</kwd><kwd>факоэмульсификация катаракты</kwd><kwd>метод Ямане</kwd><kwd>коррекция афакии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic endophthalmitis</kwd><kwd>cataract phacoemulsification</kwd><kwd>Yamane method</kwd><kwd>aphakia correction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rahmani S, Eliott D. Postoperative endophthalmitis: a review of risk factors, prophylaxis, incidence, microbiology, treatment, and outcomes. Semin Ophthalmol. 2018; 33(1): 95-101. doi: 10.1080/08820538.2017.1353826</mixed-citation><mixed-citation xml:lang="en">Rahmani S, Eliott D. 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