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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2026-11.1.4</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-5889</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКУШЕРСТВО И ГИНЕКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OBSTETRICS AND GYNAECOLOGY</subject></subj-group></article-categories><title-group><article-title>Распространенность нарушений менструальной функции у девушек-подростков с учетом гинекологического возраста: кросс-секционное исследование</article-title><trans-title-group xml:lang="en"><trans-title>Prevalence of menstrual disorders in adolescent girls with taking into account gynecologic age: a cross-sectional study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6847-9810</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Егорова</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Egorova</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Егорова Ирина Юрьевна – аспирант.</p><p>664003, Иркутск, ул. Тимирязева, 16</p></bio><bio xml:lang="en"><p>Irina Yu. Egorova - postgraduate student of the Laboratory of gynecology, andrology and reproduction, Scientific Centre for Family Health and Human Reproduction Problems.</p><p>Timiryazev Str., 16, Irkutsk 664003</p></bio><email xlink:type="simple">egorovairina1994@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7662-8529</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лазарева</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lazareva</surname><given-names>L. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лазарева Людмила Михайловна - доктор медицинских наук, старший научный сотрудник, заведующая лабораторией гинекологии, андрологии и репродукции.</p><p>664003, Иркутск, ул. Тимирязева, 16</p></bio><bio xml:lang="en"><p>Ludmila M. Lazareva - Dc. Sc. (Med.), senior research officer, Head of the Laboratory of gynecology, andrology and reproduction, Scientific Centre for Family Health and Human Reproduction Problems.</p><p>Timiryazev Str., 16, Irkutsk 664003</p></bio><email xlink:type="simple">lirken_@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5747-7315</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Наделяева</surname><given-names>Я. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Nadeliaeva</surname><given-names>Ya. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наделяева Яна Геннадьевна - кандидат медицинских наук, научный сотрудник лаборатории гинекологической эндокринологии.</p><p>664003, Иркутск, ул. Тимирязева, 16</p></bio><bio xml:lang="en"><p>Iana G. Nadeliaeva - Cand. Sc. (Med.), Research Officer at the Laboratory of gynecological endocrinology, Scientific Centre for Family Health and Human Reproduction Problems.</p><p>Timiryazev Str., 16, Irkutsk 664003</p></bio><email xlink:type="simple">ianadoc@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8862-5771</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данусевич</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Danusevich</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Данусевич Ирина Николаевна - доктор медицинских наук, заведующая лабораторией гинекологической эндокринологии.</p><p>664003, Иркутск, ул. Тимирязева, 16</p></bio><bio xml:lang="en"><p>Irina N. Danusevich - Dc. Sc. (Med.), Head of the Laboratory of gynecological endocrinology, Scientific Centre for Family Health and Human Reproduction Problems.</p><p>Timiryazev Str., 16, Irkutsk 664003</p></bio><email xlink:type="simple">irinaemails@gmail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4904-3709</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беленькая</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Belenkaia</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беленькая Лилия Васильевна - доктор медицинских наук, старший научный сотрудник лаборатории физиологии и патологии эндокринной системы.</p><p>664003, Иркутск, ул. Тимирязева, 16</p></bio><bio xml:lang="en"><p>Lilia V. Belenkaya - Dc. Sc. (Med.), senior research officer at the Laboratory of physiology and pathology of the endocrine system, Scientific Center for Family and Human Health Problems.</p><p>Timiryazev Str., 16, Irkutsk 664003</p></bio><email xlink:type="simple">Drblv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3407-9365</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аталян</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Atalyan</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аталян Алина Валерьевна - кандидат биологических наук, старший научный сотрудник лаборатории гинекологии, андрологии и репродукции.</p><p>664003, Иркутск, ул. Тимирязева, 16</p></bio><bio xml:lang="en"><p>Alina V. Atalyan - Cand. Sc. (Biol.), senior research officer at the Laboratory of gynecology, andrology and reproduction, Scientific Centre for Family Health and Human Reproduction Problems.</p><p>Timiryazev Str., 16, Irkutsk 664003</p></bio><email xlink:type="simple">alinaa@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7604-6246</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабаева</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Babaeva</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бабаева Наталья Игоревна - младший научный сотрудник лаборатории гинекологической эндокринологии.</p><p>664003, Иркутск, ул. Тимирязева, 16</p></bio><bio xml:lang="en"><p>Natalia I. Babaeva - junior researcher at the Laboratory of gynecological endocrinology, Scientific Centre for Family Health and Human Reproduction Problems.</p><p>Timiryazev Str., 16, Irkutsk 664003</p></bio><email xlink:type="simple">miracle_909@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-9442-5219</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивкина</surname><given-names>Д. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivkina</surname><given-names>D. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ивкина Дарья Олеговна - лаборант-исследователь лаборатории гинекологии, андрологии и репродукции.</p><p>664003, Иркутск, ул. Тимирязева, 16</p></bio><bio xml:lang="en"><p>Daria O. Ivkina - associate researcher at the Laboratory of gynecology, andrology and reproduction, Scientific Centre for Family Health and Human Reproduction Problems.</p><p>Timiryazev Str., 16, Irkutsk 664003</p></bio><email xlink:type="simple">iphr@sbamsr.irk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-7831-3397</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Машукова</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Mashukova</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Машукова Анастасия Константиновна - лаборант-исследователь лаборатории гинекологии, андрологии и репродукции.</p><p>664003, Иркутск, ул. Тимирязева, 16</p></bio><bio xml:lang="en"><p>Anastasia K. Mashukova - research assistant at the Laboratory of gynecology, andrology and reproduction, Scientific сentre for family health and human reproduction problems.</p><p>Timiryazev Str., 16, Irkutsk 664003</p></bio><email xlink:type="simple">imshel@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6271-7803</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сутурина</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Suturina</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сутурина Лариса Викторовна - доктор медицинских наук, профессор, главный научных сотрудник, руководитель отдела охраны репродуктивного здоровья.</p><p>664003, Иркутск, ул. Тимирязева, 16</p></bio><bio xml:lang="en"><p>Larisa V. Suturina - Dc. Sc. (Med.), Professor, leading research officer, Head of the Department of Reproductive Health, Scientific Centre for Family Health and Human Reproduction Problems.</p><p>Timiryazev Str., 16, Irkutsk 664003</p></bio><email xlink:type="simple">lsuturina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научный центр проблем здоровья семьи и репродукции человека»</institution></aff><aff xml:lang="en"><institution>Scientific Centre for Family Health and Human Reproduction Problems</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>26</day><month>03</month><year>2026</year></pub-date><volume>11</volume><issue>1</issue><fpage>34</fpage><lpage>49</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Егорова И.Ю., Лазарева Л.М., Наделяева Я.Г., Данусевич И.Н., Беленькая Л.В., Аталян А.В., Бабаева Н.И., Ивкина Д.О., Машукова А.К., Сутурина Л.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Егорова И.Ю., Лазарева Л.М., Наделяева Я.Г., Данусевич И.Н., Беленькая Л.В., Аталян А.В., Бабаева Н.И., Ивкина Д.О., Машукова А.К., Сутурина Л.В.</copyright-holder><copyright-holder xml:lang="en">Egorova I.Y., Lazareva L.M., Nadeliaeva Y.G., Danusevich I.N., Belenkaia L.V., Atalyan A.V., Babaeva N.I., Ivkina D.O., Mashukova A.K., Suturina L.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/5889">https://www.actabiomedica.ru/jour/article/view/5889</self-uri><abstract><p>Нарушения менструальной функции (НМФ) у подростков являются предиктором репродуктивных расстройств в более старшем возрасте, при этом данные о распространенности НМФ у девушек-подростков разноречивы.</p><sec><title>Цель исследования</title><p>Цель исследования. Оценить распространённость нарушений менструальной функции в городской субпопуляции 14-17-летних девушек-подростков с учетом их гинекологического возраста.</p></sec><sec><title>Методы</title><p>Методы. Проведено поперечное исследование (2020-2023 гг.), в котором приняли участие 417 девушек-подростков, учащихся 1-2 курсов педагогического колледжа, а также 9-11 классов Лицея № 3 и Школы № 14 г. Иркутска. В исследовании применялся метод анкетного опроса, а также общеклиническое обследование. Оценивалась частота нарушений менструальной функции. Методы статистического анализа включали описательную статистику и тестирование статистических гипотез.</p></sec><sec><title>Результаты</title><p>Результаты. Обследовано 417 девушек-подростков в возрасте 16,18 ± 0,7 лет. Нарушения менструальной функции (НМФ) выявлены у 56,35 % (235/417) девушек, причём часто отмечалось более одного вида нарушений. Наиболее распространенным нарушением была олигоменорея, которая встречалась как изолированно, так и в сочетании с другими дисфункциями, и в целом составила 31,17 % (130/417), аномальными маточными кровотечениями (АМК) страдали 23,3 % девушек подростков (97/417), а дисменореей - 20,62 % (86/417). В структуре нарушений менструальной функции изолированная олигоменорея выявлена у 29,79 % (70/235), олигоменорея в сочетании с АМК - у 15,74 % (37/235), только АМК - у 15,32 % (36/235), аменорея - у 2,55 % (6/235) подростков, изолированная дисменорея встречалась в 20,85 % случаев (49/235), а в сочетании с другими видами НМФ - у 15,74 % (37/235) обследованных.</p></sec><sec><title>Заключение</title><p>Заключение. Результаты проведенного исследования свидетельствуют о значительной частоте нарушений менструальной функции в неселективной (не госпитальной) выборке 14-17-летних учащихся девушек-подростков. Полученные данные диктуют необходимость активного выявления и коррекции нарушений становления менструального цикла - прогностически значимого маркера состояния репродуктивной системы девушек-подростков.</p></sec></abstract><trans-abstract xml:lang="en"><p>Menstrual disorders (MD) in adolescents are the predictor of reproductive problems in older age; nevertheless, the data on the prevalence of MD in adolescent girls are controversial.</p><sec><title>The aim</title><p>The aim. To estimate the prevalence of menstrual disorders in the urban subpopulation of 14-17-year-old adolescent girls taking into account their gynecological age.</p></sec><sec><title>Methods</title><p>Methods. A cross-sectional study (2020-2023) was conducted with the participation of 417 adolescent girls - students of 1-2 years of pedagogical college, students of 9-11 grades of Lyceum No. 3, and School No. 14 in Irkutsk. The study used a questionnaire survey method and general clinical examination. The incidence of menstrual irregularity was assessed. Statistical analysis methods included descriptive statistics and statistical hypothesis testing.</p></sec><sec><title>Results</title><p>Results. Four hundred seventeen adolescent girls aged 16.18 ± 0.7 years were examined. Menstrual dysfunction (MD) was detected in 56.35 % (235/417) of girls, and more than one type of dysfunction was observed. The most common disorder was oligomenorrhea, which occurred both in isolation and in combination with other dysfunctions, and was present in 31.17 % (130/417) of the girls; 23.3 % of the girls (97/417) suffered from abnormal uterine bleeding (AUB), and 20.62 % (86/417) suffered from dysmenorrhea. In the structure of menstrual function disorders, isolated oligomenorrhea was detected in 29.79 % (70/235), oligomenorrhea in combination with AUB was detected in 15.74 % (37/235), AUB alone in 15.32 % (36/235), amenorrhea in 2.55 % (6/235) of adolescents, isolated dysmenorrhea occurred in 20.85 % of cases (49/235), and in combination with other types of MD - in 15.74 % (37/235) of the surveyed.</p></sec><sec><title>Conclusion</title><p>Conclusion. The results of the study indicate a significant frequency of menstrual disorders in a non-selective (non-hospital) sample of 14-17-year-old female adolescent students. The data obtained dictate the need for active detection and correction of menstrual cycle disorders, a prognostically significant marker of the state of the reproductive system in adolescent girls.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>олигоменорея</kwd><kwd>аменорея</kwd><kwd>АМК</kwd><kwd>дисменорея</kwd><kwd>распространенность</kwd><kwd>подростки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>oligomenorrhea</kwd><kwd>amenorrhea</kwd><kwd>AUB</kwd><kwd>dysmenorrhea</kwd><kwd>prevalence</kwd><kwd>adolescents</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена в рамках государственной тем: «Патофизиологические механизмы и генетико-метаболические предикторы сохранения репродуктивного здоровья и долголетия в различных возрастных, гендерных и этнических группах» (FGMZ-2021-0002) и «Этнодифференцированные патогенетически обоснованные методы диагностики, коррекции и профилактики нарушений репродуктивного здоровья и возраст-зависимых заболеваний как основа для персонализированного мониторинга здоровья и поддержания активного долголетия» (шифр FGMZ-2026-0016).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Уварова Е.В., Филиппов О.С., Ипполитова М.Ф., Андреева В.О., Сутурина Л.В., Караченцова И.В. и др. 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