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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2018-3.3.11</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-587</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БИОЛОГИЯ И МЕДИЦИНСКАЯ БИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BIOLOGY AND MEDICAL BIOLOGY</subject></subj-group></article-categories><title-group><article-title>Особенности сна у женщин в климактерическом периоде (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Sleep features in menopausal women (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мадаева</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Madaeva</surname><given-names>I. M.</given-names></name></name-alternatives><email xlink:type="simple">nightchild@mail.ru)</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenova</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">natkor_84@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Астафьев</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Astafyev</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">astaw48@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дружинина</surname><given-names>Е. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Druzhinina</surname><given-names>E. B.</given-names></name></name-alternatives><email xlink:type="simple">ebdru@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лабыгина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Labygina</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «научный центр проблем здоровья семьи и репродукции человека»</institution></aff><aff xml:lang="en"><institution>Scientific Centre for Family Health and Human Reproduction Problems</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Иркутская государственная медицинская академия последипломного образования - филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ГБУЗ «Иркутская ордена «Знак почёта» областная клиническая больница»; ГБУЗ «Иркутская ордена «Знак почёта» областная клиническая больница»</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Russian Medical Academy of Continuing Professional Education; Irkutsk Regional Clinical Hospital</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>28</day><month>05</month><year>2018</year></pub-date><volume>3</volume><issue>3</issue><fpage>75</fpage><lpage>81</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мадаева И.М., Семенова Н.В., Астафьев В.А., Дружинина Е.Б., Лабыгина А.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Мадаева И.М., Семенова Н.В., Астафьев В.А., Дружинина Е.Б., Лабыгина А.В.</copyright-holder><copyright-holder xml:lang="en">Madaeva I.M., Semenova N.V., Astafyev V.A., Druzhinina E.B., Labygina A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/587">https://www.actabiomedica.ru/jour/article/view/587</self-uri><abstract><p>В статье приводится обзор литературы отечественных и зарубежных исследователей, посвящённый сомнологическим аспектам климактерического периода у женщин. Показаны возрастные изменения в структурной организации сна при дефиците половых стероидов, в т. ч. и в гендерном аспекте. Выявлена высокая частота нарушений сна у женщин в климактерическом периоде (от 39 % в перименопаузе до 60 % в постменопаузальном периоде). При этом результаты исследований относительно жалоб на нарушения сна в зависимости от фазы климактерия неоднозначны, что может быть обусловлено этнической принадлежностью. Приведены данные по некоторым патогенетическим механизмам формирования наиболее частых нарушений сна у женщин в климактерическом периоде - инсомнии, синдрома обструктивного апноэ сна и фибромиалгии. Представлены результаты полисомнографического мониторинга при данных патологических состояниях, свидетельствующие об уменьшении эффективности сна, изменении его «архитектуры» и более продолжительном времени бодрствования в течение ночи при инсомнии; значительное увеличение индекса апноэ/гипопноэ, задержка фазы быстрого сна, уменьшение продолжительности глубоких стадий сна и снижение его эффективности - при синдроме обструктивного апноэ сна. Отмечены социальные и медицинские последствия нарушений сна и их коморбидность с такими патологическими состояниями, как психические нарушения, ожирение, заболевания сердечно-сосудистой системы, онкология, нарушения углеводного обмена, бронхиальная астма, смертность.</p></abstract><trans-abstract xml:lang="en"><p>The article reviews the literature of domestic and foreign researchers devoted to the somnological aspects of the menopausal period in women. Age-related changes in the structural organization of sleep are shown with a deficiency of sex steroids, also and in the gender aspect. A high frequency of sleep disorders in menopausal women, reaching 60 %, has been revealed. However, the results of studies on complaints of sleep disorders depending on the climacteric phase are ambiguous, which may be due to ethnicity. Data on some pathogenetic mechanisms of the formation of the most frequent sleep disorders in menopausal women - insomnia, obstructive sleep apnea syndrome and fibromyalgia - are described. The results of polysomnography in these pathological states are presented, indicating a decrease in sleep efficiency, a change in its "architecture", and a longer waking time during the night with insomnia; a significant increase in the apnea/hypopnea index, a delay in the phase of fast sleep, a decrease in the duration of deep stages of sleep and a decrease in its effectiveness - in obstructive sleep apnea syndrome. The social and medical consequences of sleep disorders and their comorbidity with such pathological conditions as mental disorders, obesity, cardiovascular diseases, oncology, disorders of carbohydrate metabolism, bronchial asthma, mortality are noted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сон</kwd><kwd>климактерий</kwd><kwd>инсомния</kwd><kwd>синдром обструктивного апноэ сна</kwd><kwd>фибромиалгия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sleep</kwd><kwd>menopause</kwd><kwd>insomnia</kwd><kwd>obstructive sleep apnea syndrome</kwd><kwd>fibromyalgia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Вейн А.М. Сон человека. Физиология и патология. - М.: Медицина, 2000. - 272 с</mixed-citation><mixed-citation xml:lang="en">Вейн А.М. Сон человека. 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