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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2018-3.3.8</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-584</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКУШЕРСТВО И ГИНЕКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OBSTETRICS AND GYNAECOLOGY</subject></subj-group></article-categories><title-group><article-title>Факторы риска наружнего генитального эндометриоза</article-title><trans-title-group xml:lang="en"><trans-title>Risk factors for external genital endometriosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Червов</surname><given-names>В. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Chervov</surname><given-names>V. O.</given-names></name></name-alternatives><email xlink:type="simple">v.chervov@mai.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артымук</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Artymuk</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">roddom_kokb@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данилова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Danilova</surname><given-names>L. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Kemerovo State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГАУЗ КО «Областной клинический перинатальный центр им. Л.А. Решетовой»</institution></aff><aff xml:lang="en"><institution>L.A. Reshetova Kemerovo Regional Perinatal Centre</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>28</day><month>05</month><year>2018</year></pub-date><volume>3</volume><issue>3</issue><fpage>54</fpage><lpage>58</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Червов В.О., Артымук Н.В., Данилова Л.Н., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Червов В.О., Артымук Н.В., Данилова Л.Н.</copyright-holder><copyright-holder xml:lang="en">Chervov V.O., Artymuk N.V., Danilova L.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/584">https://www.actabiomedica.ru/jour/article/view/584</self-uri><abstract><p>Одной из наиболее распространённых форм нарушения репродуктивной системы женщины является эндометриоз. Предполагается, что генетическая предрасположенность и факторы окружающей среды тесно связаны с развитием эндометриоза. Однако несмотря на высокую распространённость эндометриоза среди женщин репродуктивного возраста, факторы риска или маркеры развития заболевания остаются в значительной степени неизвестными. Цель работы - выявить факторы риска наружного генитального эндометриоза у женщин, проживающих в Кемеровской области. Материалы и методы. Дизайн исследования - ретроспективное исследование типа «случай - контроль». В исследование включены 154 женщины. В I группу вошли 77 женщин с гистологически подтвержденным наружным генитальным эндометриозом, во II группу - 77 женщин без генитального эндометриоза, которым была проведена лапароскопия по поводу различных заболеваний органов малого таза. Результаты. Результаты проведенного исследования показали, что наиболее значимыми факторами риска эндометриоза являются ранее наступление менархе (&lt; 11 лет), укороченный менструальный цикл с продолжительными менструациями, активное и пассивное курение, наличие печного отопления и миомы матки, семейный анамнез рака молочной железы. Типичными жалобами пациенток с эндометриозом является тазовая боль, дисменорея и диспареуния. Выводы. Необходимы дальнейшие исследования для изучения значимости этих факторов при диагностике эндометриоза и понимании его этиологии.</p></abstract><trans-abstract xml:lang="en"><p>One of the most common forms of violation of the reproductive system of a woman is endometriosis. It is assumed that the genetic predisposition and environmental factors are closely related to the development of endometriosis. However, despite the high prevalence of endometriosis among women of reproductive age, the risk factors or markers for the development of the disease remain largely unknown. The aim of the study was to identify risk factors for external genital endometriosis. Materials and methods. Study design: retrospective case-control. The study included 154 women. Group I included 77 women with histologically verified external genital endometriosis. Group II consisted of 77 women without endometriosis, who underwent endoscopic surgery due to various diseases of the pelvic organs. Results. The results of the study showed that the most significant risk factors for endometriosis are the early onset of menarche (&lt; 11 years), a shortened menstrual cycle with prolonged menstruation, active and passive smoking, the presence of furnace heating and uterine fibroids, a family history of breast cancer. Typical complaints of patients with endometriosis are pelvic pain, dysmenorrhea and dyspareunia. Conclusions. Further studies are needed to study the significance of these factors in the diagnosis of endometriosis and the understanding of its etiology.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эндометриоз</kwd><kwd>факторы риска</kwd><kwd>ксенобиотики</kwd></kwd-group><kwd-group xml:lang="en"><kwd>endometriosis</kwd><kwd>risk factors</kwd><kwd>xenobiotics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Артымук Н.В., Данилова Л.Н., Червов В.О., Рыбников С.В. Эффективность комбинированного лечения бесплодия, ассоциированного с эндометриозом // Фарматека. - 2017. - № 12. - С. 56-61</mixed-citation><mixed-citation xml:lang="en">Артымук Н.В., Данилова Л.Н., Червов В.О., Рыбников С.В. 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