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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2025-10.5.14</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-5679</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОФТАЛЬМОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPHTHALMOLOGY</subject></subj-group></article-categories><title-group><article-title>Диагностические возможности компьютерной аккомодографии у лиц среднего (пресбиопического) возраста</article-title><trans-title-group xml:lang="en"><trans-title>Diagnostic capabilities of computer accommodography in middleaged (presbyopic) individuals</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4875-0535</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зеленцов</surname><given-names>Р. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zelentsov</surname><given-names>R. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зеленцов Роман Николаевич – кандидат медицинских наук, доцент кафедры семейной медицины и внутренних болезней</p><p>163000, г. Архангельск, пр. Троицкий, д. 51, Россия </p></bio><bio xml:lang="en"><p>Roman N. Zelentsov – Cand. Sc. (Med), Associate Professor of the Department of Family Medicine and Internal Diseases </p><p>Troitskiy ave., 51, 163000 Arkhangelsk, Russian Federation </p></bio><email xlink:type="simple">zelentsovrn@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-1462-2832</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузнецова Евгения Иннокентьевна – студентка 6 курса Педиатрического факультета</p><p>163000, г. Архангельск, пр. Троицкий, д. 51, Россия </p></bio><bio xml:lang="en"><p>Evgeniya I. Kuznetsova – 6th–year student at the Faculty of Pediatrics</p><p>Troitskiy ave., 51, 163000 Arkhangelsk, Russian Federation </p></bio><email xlink:type="simple">evgeniaroza2020@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7537-0837</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поскотинова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Poskotinova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Поскотинова Лилия Владимировна – доктор биологических наук, кандидат медицинских наук,  доцент, главный научный сотрудник, заведующая  лабораторией биоритмологии Института физиологии природных адаптаций; профессор кафедры семейной медицины и внутренних болезней</p><p>163000, г. Архангельск, пр. Троицкий, д. 51, Россия </p><p>163029, г. Архангельск, пр. Никольский, д.20, Россия</p></bio><bio xml:lang="en"><p>Liliya V. Poskotinova – Dr. Sc. (Biol.), Cand. Sc. (Med.), Associated Professor, Chief Scientific Resercher, Head of the Biorhythmology Laboratory, Instituteof Environmental Physiology; Professor of the Department of Family Medicine and Internal Diseases</p><p>Troitskiy ave., 51, 163000 Arkhangelsk, Russian Federation </p><p>Nikolsky Ave., 20, 163029 Arkhangelsk, Russian Federation</p></bio><email xlink:type="simple">liliya200572@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-6587-7149</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синайская</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinayskaya</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Синайская Мария Александровна – кандидат медицинских наук, доцент кафедры семейной медицины и внутренних болезней</p><p>163000, г. Архангельск, пр. Троицкий, д. 51, Россия </p></bio><bio xml:lang="en"><p>Mariya A. Sinayskaya – Cand. Sc. (Med), Associate Professor of the Department of Family Medicine and Internal Diseases</p><p>Troitskiy ave., 51, 163000 Arkhangelsk, Russian Federation </p></bio><email xlink:type="simple">msinayskaya@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8902-8947</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудрявцев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudryavtsev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кудрявцев Александр Валерьевич – кандидат медицинских наук, заведующий международным центром научных компетенций Центральной научно-исследовательской лаборатории</p><p>163000, г. Архангельск, пр. Троицкий, д. 51, Россия </p></bio><bio xml:lang="en"><p>Alexander V. Kudryavtsev – Cand. Sc. (Med), Head of International Research Competence Centre, Central Scientific Research Laboratory</p><p>Troitskiy ave., 51, 163000 Arkhangelsk, Russian Federation </p></bio><email xlink:type="simple">ispha09@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Северный государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Northern State Medical University of the Ministry of Health of the Russian Federation</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Северный государственный медицинский университет» Министерства здравоохранения Российской Федерации;&#13;
ФГБУН «Федеральный исследовательский центр комплексного изучения Арктики им. акад. Н.П. Лаверова» УрО РАН</institution></aff><aff xml:lang="en"><institution>Northern State Medical University of the Ministry of Health of the Russian Federation;&#13;
N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>17</day><month>12</month><year>2025</year></pub-date><volume>10</volume><issue>5</issue><fpage>122</fpage><lpage>131</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зеленцов Р.Н., Кузнецова Е.И., Поскотинова Л.В., Синайская М.А., Кудрявцев А.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Зеленцов Р.Н., Кузнецова Е.И., Поскотинова Л.В., Синайская М.А., Кудрявцев А.В.</copyright-holder><copyright-holder xml:lang="en">Zelentsov R.N., Kuznetsova E.I., Poskotinova L.V., Sinayskaya M.A., Kudryavtsev A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/5679">https://www.actabiomedica.ru/jour/article/view/5679</self-uri><abstract><p>Обоснование. Изучение пресбиопии направлено на улучшение качества жизни стареющего населения посредством коррекции зрения вблизи и своевременной коррекции аккомодационных нарушений у пресбиопов, в особенности сочетающихся с гиперметропической и миопической рефракцией.Цель исследования. Оценить основные параметры компьютерной аккомодографии у лиц 45–59 лет с пресбиопией в сочетании с гиперметропической и миопической рефракцией.Методы. Проведено поперечное исследование случайной выборки населения г. Архангельска 45–59 лет (n = 69), включавшее офтальмологическое обследование с комплексным исследованием аккомодации. В анализ включены данные 127 глаз. Участники были разделены на 5 групп: лица с установленным диагнозом «миопия» (слабой, средней и высокой степени), лица с пресбиопией (с эмметропией) и лица, у которых пресбиопия сопровождалась гиперметропией с величиной рефракции до 3,0 дптр включительно.Результаты. В 32,3 % случаев (41 глаз) не было выявлено патологии органа зрения за исключением пресбиопии. Наличие миопической рефракции выявлено в 46,5 % случаев (59 глаз) и среднее значение рефракции в данной группе участников составило -3,26 ± 0,13 диоптрий. При сравнении групп по количественным параметрам аккомодограмм коэффициент микрофлюктуации был наиболее высок (до +3,0 дптр, включительно) в группах участников с миопией средней степени и у лиц с возрастной пресбиопией в сочетании с гиперметропией, наиболее низким – у участников пресбиопов с эмметропией, и в группах миопии слабой и высокой степеней (р = 0,028). Коэффициент микрофлюктуации был наиболее устойчив среди лиц без патологии органа зрения, за исключением возрастной пресбиопии, и у участников с миопией слабой степени (p = 0,017).Заключение. Применение компьютерной аккомодографии в офтальмологической практике может значительно расширить диагностические возможности в части определения аккомодационных изменений у лиц среднего возраста.</p></abstract><trans-abstract xml:lang="en"><p>Background. Presbyopia research aims to improve the quality of life of the aging population by correcting near vision and timely addressing accommodative disorders in presbyopes, particularly when combined with hypermetropic and myopic refraction.The aim. To assess the parameters of computer accommodography in individuals aged 45–59 with presbyopia combined with hypermetropic and myopic refraction.Methods. A cross-sectional study was conducted on a random sample of Arkhangelsk population aged 45–59 (n = 69), including ophthalmological examination with a comprehensive accommodation assessment. Data of 127 eyes were analysed. Participants were divided into five groups: those diagnosed with myopia (mild, moderate, and high degree), those with presbyopia (with emmetropia), and those with presbyopia accompanied by hypermetropia (refraction up to 3.0 D inclusive).Results. In 32.3% of cases (41 eyes), no ocular pathology was detected except for presbyopia. Myopic refraction was found in 46.5% of cases (59 eyes), with an average refraction of 3.26±0.13 D in this group. When comparing groups on quantitative accommodogram parameters, the highest microfluctuation coefficient (up to +3.0 D inclusive) was in participants with moderate myopia and in those with age-related presbyopia combined with hypermetropia, the lowest – in participants with presbyopia (with emmetropia) and in groups with mild and high myopia (p = 0.028). Microfluctuation coefficient was the most stable was in individuals without visual organ pathology, with the exception of age-related presbyopia, and among participants with mild myopia (p = 0.017).Conclusion. The use of computer accommodography in ophthalmological practice can significantly expand diagnostic capabilities for identifying accommodative changes in middle-aged individuals.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пресбиопия</kwd><kwd>компьютерная аккомодография</kwd><kwd>здоровое старение</kwd><kwd>миопия</kwd><kwd>гиперметропия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>presbyopia</kwd><kwd>computer accommodography</kwd><kwd>healthy aging</kwd><kwd>myopia</kwd><kwd>hypermetropia</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено с использованием средств гранта Российского научного фонда № 23-15- 20017, https://rscf.ru/project/23-15-20017/.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Blindness GBD, Vision Impairment C. 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