actabiomedicaActa Biomedica ScientificaActa Biomedica Scientifica2541-94202587-9596Scientific Centre for Family Health and Human Reproduction Problems10.12737/article_5a3a0d5360f938.91867142actabiomedica-499Research ArticleАКУШЕРСТВО И ГИНЕКОЛОГИЯOBSTETRICS AND GYNAECOLOGYТрихологические особенности алопеций у женщин репродуктивного возраста с синдромом поликистозных яичниковTrichology features of alopecia in reproductive age women with polycystic ovary syndromeБеленькаяЛ. В.BelenkayaL. V.Drblv@mail.ruИвановО. В.IvanovO. V.noemail@neicon.ruПанаринаО. В.PanarinaO. V.panarinaolya08@mail.ruРашидоваМ. А.RashidovaM. A.stella-m90@mail.ruШолоховЛ. Ф.SholokhovL. F.Lfshol@mail.ruФГБНУ «научный центр проблем здоровья семьи и репродукции человека»Scientific Centre for Family Health and Human Reproduction ProblemsООО «Аши-мед»; ФГБНУ «Научный центр проблем здоровья семьи и репродукции человека»OOO “Ashi-med”; Scientific Centre for Family Health and Human Reproduction Problems20172809201725(2)914Copyright © Беленькая Л.В., Иванов О.В., Панарина О.В., Рашидова М.А., Шолохов Л.Ф., 20172017Беленькая Л.В., Иванов О.В., Панарина О.В., Рашидова М.А., Шолохов Л.Ф.Belenkaya L.V., Ivanov O.V., Panarina O.V., Rashidova M.A., Sholokhov L.F.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.actabiomedica.ru/jour/article/view/499

Обоснование. Синдром поликистозных яичников (СПКЯ) является одним из наиболее распространённых эндокринных расстройству 5-10 % женщин репродуктивного возраста. Дерматологическими проявлениями СПКЯ являются: гиперандрогения, в основном гирсутизм, вульгарные угри, андрогенная алопеция и негроидный акантоз. СПКЯ - это мультифакторное нарушение обмена веществ, которое оказывает значительное влияние на качество жизни, а также на фертильность. Цель исследования: установить частоту алопеций у женщин репродуктивного возраста с клиническими признаками СПКЯ и определить наиболее значимые их трихологические особенности. Материалы и методы. Методом проспективного анализа были исследованы женщины с СПКЯ. Диагноз СПКЯ был поставлен согласно критериям ESHRE/ASRM (Роттердам, 2003). Все участницы подписали информированное согласие на обследование, в том числе на фототрихограмму. Результаты. В общей сложности в исследовании участвовали 20 женщин с СПКЯ. Средний возраст составил 28,7 ± 6,2 года. Частота олигоановуляции составляла 63,2 %, гирсутизма - 68,4 %. В нашем исследовании выявлены следующие особенности алопеций у женщин, больных СПКЯ: андрогенная алопеция - в 30 % случаев, телогенное выпадение волос - в 55 % случаев, отсутствие признаков алопеции - в 15 % случаев. Заключение. Алопеция является распространённым, но ненадёжным маркером биохимического гиперандрогенизма, поэтому лечащим врачам необходимо понять неблагоприятные эффекты, связанные с СПКЯ, и признать эти потенциальные риски для здоровья пациентов и, соответственно, лечить их.

Background. Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders, affecting 5-10 % of reproductive-aged women. The dermatologic manifestations of PCOS play a significant role in diagnosis. The purpose of the present study was to examine the impact of androgenic alopecia among patients with PCOS and to define their most significant trkhological features. Because the data on dermatologic changes associated with PCOS are rather scarce, the present study was designed to determine the incidence and prevalence of androgenic alopecia. Materials and methods. We conducted a prospective observational study of patients with PCOS. The diagnosis of PCOS was made according to the consensus criteria adopted in May2003 in Rotterdam. Each patient signed informed consent, and then a general physical examination, systemic examination, breast and pelvic examination, as well as a detailed trichological examination were carried out. Results. Twenty women with PCOS participated in the study. The median age was28.7± 6.2years. Oligo/anovulation frequency was 63.2 %, hirsutism frequency - 68.4 %. In our study, the prevalence of androgenic alopecia was found to be 30 %, telogenic hair loss - 55 %, absence of alopecia signs in І5 % of cases. Conclusions. Androgenic alopecia is a prevalent but unreliable marker of biochemical hyperandrogenism. It is therefore imperative for the treating physicians to understand the adverse effects associated with PCOS, recognize these potential health risks in patients, and treat them accordingly.

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The authors declare that there are no conflicts of interest present.