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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2023-8.3.16</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-4218</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОФТАЛЬМОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPHTHALMOLOGY</subject></subj-group></article-categories><title-group><article-title>Клинический случай склерохориодиальной кальцификации</article-title><trans-title-group xml:lang="en"><trans-title>Case report of sclerochoroidal calcification</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7011-4220</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чупров</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Chuprov</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чупров Александр Дмитриевич – доктор медицинских наук, профессор, директор</p><p>460047, г. Оренбург, ул. Салмышская, 17, Россия </p></bio><bio xml:lang="en"><p>Aleksandr D. Chuprov – Dr. Sc. (Med.), Professor, Director</p><p>Salmyshskaya str. 17, Orenburg 460047, Russian Federation </p></bio><email xlink:type="simple">office@mail.ofmntk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8204-4132</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синькова</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinkova</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Синькова Виктория Игоревна – врач-офтальмолог</p><p>460047, г. Оренбург, ул. Салмышская, 17, Россия </p></bio><bio xml:lang="en"><p>Viktoriia I. Sinkova – Ophtalmologist</p><p>Salmyshskaya str. 17, Orenburg 460047, Russian Federation </p></bio><email xlink:type="simple">doc.kuznetsova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0913-6660</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Субханкулова</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Subkhankulova</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Субханкулова Алия Радиковна – врач-офтальмолог</p><p>460047, г. Оренбург, ул. Салмышская, 17, Россия </p></bio><bio xml:lang="en"><p>Aliya R. Subkhankulova – Ophtalmologist </p><p>Salmyshskaya str. 17, Orenburg 460047, Russian Federation </p></bio><email xlink:type="simple">aliya.subkhankulova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8903-6012</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барышников</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Baryshnikov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Барышников Иван Анатольевич – врач-рентгенолог</p><p>460026, г. Оренбург, просп. Победы, 116/2, Россия </p></bio><bio xml:lang="en"><p>Ivan A. Baryshnikov – Radiologist</p><p>Pobedy ave. 116/2, Orenburg 460026, Russian Federation </p></bio><email xlink:type="simple">kmfdm_89@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Оренбургский филиал ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» имени академика С.Н. Фёдорова» Минздрава России</institution></aff><aff xml:lang="en"><institution>Orenburg Branch of the S. Fyodorov Eye Microsurgery Federal State Institution</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО «Современная МРТ-томография»</institution></aff><aff xml:lang="en"><institution>OOO “Modern MRI Tomography”</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>11</day><month>07</month><year>2023</year></pub-date><volume>8</volume><issue>3</issue><fpage>145</fpage><lpage>153</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чупров А.Д., Синькова В.И., Субханкулова А.Р., Барышников И.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Чупров А.Д., Синькова В.И., Субханкулова А.Р., Барышников И.А.</copyright-holder><copyright-holder xml:lang="en">Chuprov A.D., Sinkova V.I., Subkhankulova A.R., Baryshnikov I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/4218">https://www.actabiomedica.ru/jour/article/view/4218</self-uri><abstract><sec><title>Обоснование</title><p>Обоснование. Cклерохориоидальная кальцификация – это идиопатическое редкое доброкачественное образование склеры или сосудистой оболочки, характеризующееся гистологическим отложением пирофосфата кальция. Учитывая схожие клинические проявления с другими заболеваниями склеры, большую опасность из которых представляют злокачественные, имеет значение своевременная верификация диагноза с назначением дальнейшего периода наблюдения.</p></sec><sec><title>Цель</title><p>Цель. Описание клинического случая склерохориоидальной кальцификации для повышения эффективности выявления заболевания путём применения мультимодальной диагностики.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Пациентка 62 лет с жалобами на «яркие вспышки» перед левым глазом последние несколько месяцев, которой был проведён стандартный комплекс офтальмологического обследования, дополненный по показаниям оптической когерентной томографией перипапиллярных нервных волокон, макулярной зоны, В-сканированием, допплерографией в режиме цветного доплеровского картирования. Вспомогательными методами диагностики являлись магнитно-резонансная томография орбит и экстраокулярных мышц, компьютерная томография орбит и биохимический анализ крови.</p></sec><sec><title>Результаты</title><p>Результаты. Учитывая анамнез, отсутствие прогрессии жалоб, данные инструментальных методов диагностики, отсутствие патологического кровотока в области образований обоих глаз правомерным диагнозом, вероятнее всего, будет склерохориоидальная кальцификация глаз, несмотря на трудности диагностического процесса, которые заключались в отсутствии визуализации очагов при офтальмоскопии.</p></sec><sec><title>Выводы</title><p>Выводы. Склерохориоидальная кальцификация представляет интерес для практикующих офтальмологов ввиду трудностей диагностического поиска и дифференциальной диагностики со злокачественными новообразованиями. Современная медицина располагает достаточным набором инструментальных и лабораторных методов исследования для постановки точного диагноза.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Sclerochoroidal calcification is an idiopathic rare benign lesion of the sclera or choroid characterized by histological deposition of calcium pyrophosphate. Taking into consideration its similar clinical manifestations with other diseases of the sclera, the most dangerous of which are malignant, timely verification of the diagnosis with the appointment of a further observation period is important.</p></sec><sec><title>The aim</title><p>The aim. The description of a clinical case of sclerochoroidal calcification to improve the efficiency of disease detection through the use of multimodal diagnostics.</p></sec><sec><title>Material and methods</title><p>Material and methods. A 62-year-old patient with complaints of “bright flashes” in her left eye for the past few months, who underwent a standard complex of ophthalmological examinations, supplemented according to indications by optical coherence tomography of peripapillary nerve fibers, macular zone, B-scan, Dopplerography in color Doppler mapping mode. Auxiliary diagnostic methods were magnetic resonance imaging of the orbits and extraocular muscles, computed tomography of the orbits and a biochemical blood test.</p></sec><sec><title>Results</title><p>Results. Considering the anamnesis, the absence of progression of complaints, the data of instrumental diagnostic methods, the absence of pathological blood flow in the area of both eyes formations, the correct diagnosis is most likely to be sclerochoroidal calcification of both eyes, despite the difficulties of the diagnostic process, which consisted in the absence of visualization of foci during ophthalmoscopy.</p></sec><sec><title>Conclusion</title><p>Conclusion. Sclerochoroidal calcification is of interest to practicing ophthalmologists due to the difficulties of diagnostic search and differential diagnosis with malignant neoplasms. Modern medicine has a sufficient set of instrumental and laboratory research methods for making an accurate diagnosis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>склерохориоидальная кальцификация</kwd><kwd>минеральный обмен</kwd><kwd>компьютерная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sclerochoroidal calcification</kwd><kwd>mineral metabolism</kwd><kwd>computed tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Thomson AC, Brown GT, Dolores-Rodriguez A, Hunter AA. A case of extensive bilateral idiopathic sclerochoroidal calcification and review of literature. Int Med Case Rep J. 2021; 14: 749-755. doi: 10.2147/IMCRJ.S336237</mixed-citation><mixed-citation xml:lang="en">Thomson AC, Brown GT, Dolores-Rodriguez A, Hunter AA. A case of extensive bilateral idiopathic sclerochoroidal calcification and review of literature. 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